The Biolytic 3900 is an upgrade of the original ABI 3900 that comes packed with new hardware and reimagined software features as well as a new computer and monitor running the latest Windows operating system. The new software is built for Windows 8 and features flexible protocol construction similar to the Dr. Oligo Synthesizer. The software supports truly independent protocol operation on each bank of 12 oligos while providing the user with real-time feedback during each synthesis run. The Biolytic 3900 reduces cycle time due to the use of four drain stations rather than the original two. The chamber volume is also lower, requiring less time to pressurize and vent.