The XDUO™ Quad™ single-use mixing system supports single-use biomanufacturing in upstream and downstream mixing applications and unit operations. The XDUO mixer is designed for the mixing of buffer, media, product, and other process fluids. An evolution of the original XDM™ system, the XDUO mixer has new features and onboard instrumentation to support the application needs of the GMP manufacturing environment. The XDUO single-use mixing system is available with all instrumentation and automation features integrated as a stand-alone single-use mixing platform. The instrument panel includes a Siemens S7 1200 PLC, analog I/O cards, a four-port switch, and a four-inch monochrome HMI display.