Labfors 5 with LabCIP is a self-cleaning and self-sterilizing benchtop bioreactor. The LabCIP feature cleans and sterilizes the benchtop bioreactor automatically (e.g., overnight). This can reduce the downtime of the bioreactor and increase the time available for research. Applications include high-throughput bioprocesses, fermentation, high-throughput protein expression (e.g., antibodies), process development/process optimization, process analytical technology, and scale-down/scale-up.