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July 1, 2011 (Vol. 31 , No. 13)

Proteomics Assays

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NodeSensor™ assays are based on the protein-fragment complementation principle, and they enable visualization of protein complex dynamics within living human cells. NodeSensor assays can directly measure the activity of undruggable targets such as transcription factors and proteasome components, as well as mainstream drug targets (like GPCRs) within their natural cellular context. When combining different NodeSensor assays with high-content analysis, a range of cellular responses becomes visible.

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