Chromabolt™ columns are designed for pilot-stage and early-clinical-stage manufacturing. They are offered in three sizes—internal diameters are 10, 20, and 32 cm—and they are available with Fractogel® SO3, Fractogel TMAE HiCap, and Eshmuno® S resins. Each prepacked column is prevalidated, which means that it should meet the bioburden, endotoxin, HETP, and asymmetry specifications for the resin it contains. Chromabolt columns are designed to have accessible inlets and outlets and to offer faster set-up times compared to traditional columns. Meant to be transportable by a single person, the 20 cm and 32 cm columns are on wheels.