The K-1000S and K-2700S PI3-Kinase Activity Assays measure PI3-Kinase activity via the detection of the lipid product PI(3,4,5)P3. The K-1000S PI3-Kinase Pico Assay is an ELISA that does not require any special instruments or filter sets; only a basic absorbance plate reader is needed. The K-2700S PI3-Kinase TR-FRET Assay is useful for high-throughput screening.