AdvanceBio peptide mapping columns are designed to provide high-resolution peptide maps for protein identification and determination of post-translation modifications. These columns provide the ability to resolve and identify amino acid substitutions/modifications in a protein primary sequence. These biocolumns are superficially porous and have a 120Å pore size, which works well for the analysis of the peptides produced by enzymatic digest of proteins. The 2.7 µm particle size enables UHPLC performance on HPLC systems, which can deliver high resolution.