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December 1, 2011 (Vol. 31 , No. 21)

PEG Immunogenicity ELISA Kits

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ANP Technologies

Polyethylene glycol (PEG) polymers have been used to attach to biotherapeutic molecules to improve in vivo drug delivery. PEG itself may also be capable of eliciting immune responses in patients. This universal double antigen bridging PEGIM ELISA can detect antibodies to PEG polymer adducts of various sizes and linking groups. The kit includes all reagents for the assay, along with an anti-PEG monoclonal IgM antibody as a positive control. The ELISA kit is best suited for immunogenicity testing of PEGylated proteins with molecular weights of the PEG segment ranging from 10 KDa to 40 KDa.

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