Designed for PCR, real-time PCR (qPCR), and Droplet Digital™ PCR (ddPCR™) applications, the PX1 PCR plate sealer and associated heat sealing films and foils can remove human variability from plate sealing and prevent sample evaporation from impacting results. The semi-automated design of the PX1 PCR plate sealer reduces manual sealing, using heat and pressure to seal PCR plates.