The LightCycler® 96 System offers reproducible data generation for researchers working in a range of fields such as gene expression and genetic variation research. The system permits adaptation of workflows to specific assay formats and throughput needs. It also provides guided navigation and software for first-time users as well as a full set of analytical capabilities for experienced operators. The data generated by the system can be analyzed directly or remotely for translation to publication-ready results in line with MIQE guidelines.