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January 1, 2012 (Vol. 32 , No. 1)

Nonviral Gene Transfection

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The magnefect-nano II™ facilitates gene transfection with a range of difficult cell types such as neuronal and primary cells. It uses a technology that applies magnet configurations and oscillating magnet arrays, which can operate at user-definable variable frequencies, to promote magnetic nanoparticle/DNA uptake into cells to improve nonviral gene transfection, while maintaining high cell viability. The device helps provide improved transfection efficiency at short transfection times (<30 minutes). It allows re-transfection as well as adherent state transfection for user flexibility. Interchangeable 6-well, 24-well, and 96-well array formats are available, as well as variable oscillating frequency capability.

  • nanoTherics
  • Guy Hilton Research Centre
  • Thornburrow Drive
  • Stoke-on-Trent , ST4 7QB

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