The qBiomarker™ Somatic Mutation PCR Array system is useful for mutation profiling in basic research and drug discovery. The assays are available in 96- or 384-well plate formats for a number of pathways (EGFR, ErbB2, etc.) and cancer types. The experiments require approximately two hours from sample to result. The DNA is extracted from the sample, amplified if needed, and then used for the PCR array with any block-based real-time cycler. The mutations covered in the arrays have been selected from comprehensive databases and literature reviews based on their biological relevance and frequency of occurrence.