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January 15, 2014 (Vol. 34 , No. 2)

Multiwell Plates for 3D Cell Culture

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AMS Biotechnology

AlvetexScaffold 3D cell culture technology—previously available in 12-, 24-, and 96-well formats, as well as with 6-well and 12-well inserts—is now available in a 384-well format, providing a new tool for cell-based high-throughput testing. The technology, which is designed to work with liquid handling robotic systems, can facilitate the screening of novel drugs or drug combinations on 3D culture and co-culture models, the study of cell-cell or cell-matrix interactions, the growth of cells at the air-liquid interface, and the long-term culture of cells. A typical application for the 384-well plates is in cancer cell cytotoxicity testing, mimicking in vivo growth conditions.

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