The new FluoView® FV1200MPE multiphoton biological laser scanning imaging system is designed to deliver optimal live cell and tissue imaging. It offers increased laser selection, cooled high-sensitivity detector technology, increased scanhead light throughput, and new software features designed for high-speed functional measurements. The system can be built on the IX83® automated inverted microscope platform in addition to its BX61WI® microscope for dipping-lens and live-animal applications.