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December 1, 2012 (Vol. 32 , No. 21)

Methylated Gene Targeting

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Cellectis bioresearch

TALEN™ CpG™ is a service designed to overcome the impact of methylated DNA on TALEN nuclease activity. Users can target any gene at any position in any cell type regardless of methylation status. The service can make gene editing accessible for therapeutic applications, cancer studies, and stem cell research. Chemical de-methylation of endogenous targets is no longer necessary.

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