The Eksigent ekspert™ nanoLC 400 system is a plug-and-play liquid chromatography system that integrates nano LC and micro LC on the same platform. This flexibility enables switching between high-sensitivity discovery proteomics and high-throughput targeted peptide quantitation. The interchangeable LC flow modules in the nanoLC 400 system allow scientists to go from low-flow nano LC to a higher flow rate of micro LC by switching a module, which can help with mixing nontargeted and targeted approaches.