Assay kits utilizing AlphaLISA® technology can aid in the safety testing, manufacturing, and quality control of biotherapeutic drugs. The kits can achieve high-quality results, which can help to accelerate the drug discovery process. AlphaLISA technology also has a protocol with a reduced number of assay steps, which can result in better inter- and intra-assay precision, improved coefficient of variations, and easier method transfer to downstream departments due to reduced variability.