Modified polyethersulfone (mPES) hollow fiber filters are designed for tangential flow filtration. mPES is a hydrophilic membrane chemistry that helps provide higher flux rates for faster processing, improved selectivity for separation applications, and low protein binding to promote higher production yields. mPES hollow fiber filters offer the features of mPES chemistry in fully encapsulated filter modules. mPES filters can be used in a range of tangential flow ultrafiltration applications including virus clarification and purification, liposome purification and diafiltration, and protein purification and concentration. The filters are available in 10 kD, 30 kD, 50 kD, 100 kD, and 500 kD pore sizes.