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January 15, 2013 (Vol. 33 , No. 2)

Genetic Analyzer

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Pacific Biosciences

The PacBio® RS high-resolution genetic analyzer has undergone a software upgrade featuring additional tools for performing DNA base modification analysis and de novo genome assembly. With the release of the SMRT Analysis 1.3.3 software upgrade, customers can automatically detect common types of bacterial methylation including N6-methyladenine (6-mA), N4-methylcytosine (4-mC) and Tet-converted 5-methylcytosine (5-mC). They can also perform methyltransferase (MTase) recognition motif analysis. In addition, the new software integrates the Celera® assembler to facilitate de novo genome assembly.

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