The SurePrint G3 Human Gene-Expression v2 microarray is available with an array of probes designed using the Broad Institute’s human reference catalog of large intergenic noncoding RNAs. The microarray is part of a microarray platform with a range of over five orders of magnitude designed to detect low and high expressors. The microarray system has customizable content, allowing researchers to design microarrays relevant to their experiment. In addition to the newly available probes, the SurePrint G3 Human Gene Expression v2 microarray includes an update of mRNA content from the National Center for Biotechnology Information RefSeq gene database.