Designed for use with Biacore™ systems, Sensor Chip CM7 has the immobilization capacity required to support fragment-based screening of small molecules. The chip helps improve data quality and detection in cases where immobilization levels are unfavorable, such as low concentration of target protein or a target protein that is sensitive to optimal immobilization conditions. Sensor Chip CM7 has a carboxymethylated dextran matrix covalently attached to gold film, with a higher degree of carboxylation and a denser matrix compared to a previous version of the chip.