Introl CF Panel II Control is designed to monitor the detection of 54 CFTR mutations, genetic risk factors associated with cystic fibrosis. The 54 mutations include the 23 that are recommended for testing by ACMG and ACOG. They are contained in three bottles in heterozygous format. Introl CF Panel II Control also monitors variants I506V, I507V, F508C, 5/7/9/11T, and I148T. The CF Panel II is also available to manufacturers in ready-to-use, nonextractable formats as a custom order. The control is extractable and therefore monitors the entire assay. This product is effective for routine QC, lot-to-lot comparisons, and new method validations.