The EpiQ chromatin analysis kit is a real-time PCR assay for the quantitative assessment of chromatin structure. Complementing existing epigenetic assays such as DNA methylation and chromatin immunoprecipitation, the EpiQ kit helps scientists quantify the impact of epigenetic events on gene-expression regulation through chromatin state changes. Benefits include assessment of chromatin structure in cultured cells within six hours, requirement of relatively few cells (as few as 50,000) to perform analysis, and generation of quantitative chromatin structure information for multiple genomic elements. The EpiQ kit includes buffers for cell permeabilization and in situ chromatin digestion, optimized nuclease, materials for genomic DNA purification, control assays (qPCR primers) for chromatin assessment of a reference (epigenetically silenced) and control (constitutively expressed) gene, and EpiQ™ Chromatin SYBR® Green Supermix.