The RNAgard® blood system is an integrated system designed for the collection, preservation, and purification of RNA from whole blood samples. The system consists of Vacuette® RNAgard blood tubes and the BioMaxi™ blood RNA purification kit. Preservation of the RNA is effective for up to 14 days at room temperature, and 1 month at 4°C. This system provides RNA by maintaining expression profiles at the blood draw. The purification kit does not involve organic solvents or proteinase K digestion.