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January 1, 2012 (Vol. 32 , No. 1)

Acoustic Biosensor

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SAW Instruments

The sam®X acoustic biosensor features eight analysis channels and adaptable routing. The system uses surface acoustic wave technology to detect mass binding and protein conformational changes on whole cells. sam acoustic biosensors do not require complex labeling methods, are real-time rather than equilibrium, and can be used to investigate living cells rather than fixed cells or purified proteins. The new samX has two sensor chips. Each of the instrument’s eight channels can be used independently or via sequential combinations of 4 x 2, 2 x 4, or 1 x 8 channels. In addition, different ligands can now be immobilized online at each chip position automatically, without the need for off-line protein loading.

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