Related to Horizon and Promega Ally on Cancer Models for Development of Targeted Drug Therapies

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• Sequencing Assays
• Roche
• GS GType TET2/CBL/KRAS and the GS GType RUNX1 primer sets are designed for comprehensive genetic variation detection in four key human genes using the 454 GS Junior and GS FLX Systems. The sequence-based assays offer a solution for cancer researche
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• Bioluminescent Enzyme
• Promega
• The NanoLuc™ luciferase can provide new capabilities in reporter assays with the potential to aid with biologically complex applications that require greater sensitivity. It is small in size, allowing for viral delivery and protein fusion applicati
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• Tumor Marker Control
• Randox Laboratories
• The Acusera multianalyte liquid tumor marker control covers a total of 15 commonly tested and esoteric cancer antigens and tumor markers. Assayed target values can help laboratories monitor both accuracy and precision. The liquid stable nature redu
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• ssDNA Quantitation
• Promega
• The QuantiFluor™ ssDNA system is designed for highly sensitive quantitation of single-stranded DNA (ssDNA). The QuantiFluor ssDNA dye enables quantitation of small amounts (as little as 200 pg per well) of ssDNA in solution. For low-concentration s
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• CHO Cell Cloning
• STEMCELL Technologies
• The ClonaCell™-CHO ACF supplement improves cloning efficiency of CHO cells during cell-line development. The challenges of low cloning efficiency can result in significant waste of time and resources during single-cell cloning. The ClonaCell-CHO AC
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• Resistant-to-Inhibitor Master Mixes
• Promega
• The GoTaq® Probe PCR Master Mix, GoTaq Probe 1-Step RT-qPCR system, and GoTaq Probe 2-Step RT-qPCR system are ready-to-use, 2x master mixes that can simplify the preparation of reactions for qPCR using hydrolysis probe detection. They are desi
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• Cell-Line Customization Service
• Cellectis bioresearch
• Gene customization experts can modify cell lines at any gene, at any position. Services available include gene modification, knock-out, and targeted transgene integration. Thirteen years of genome customization expertise, TALEN™ technology, and IP
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• Dendritic Cell Generation
• HumanZyme
• The HumanKine G4 dendritic cell generation kit can yield DCs from peripheral blood mononuclear cells with no medium changes. This protocol is enabled by HumanKine GM-CSF and HumanKine IL-4, which are included in the kit and produced in a human cell
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• DNA Isolation
• Tecan
• The Freedom EVO®-HSM workstation provides walkaway extraction of gDNA from large-volume blood samples using Promega’s ReliaPrep™ large-volume HT gDNA isolation system. The workstation is designed to streamline biobanking workflows, offering on
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• Bisulfite Conversion System
• Promega
• The MethylEdge™ bisulfite system offers a method for performing bisulfite conversion and DNA clean-up while maintaining DNA integrity to provide intact, converted DNA for a range of sensitive applications. MethylEdge requires small amounts of input
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• Knockout Cell Lines for Cancer Research
• Cellectis bioresearch
• The cells in CanCELL™ cell lines represent comprehensive knockouts of major disease-relevant oncogenes and tumor suppressor genes. CanCELL cell lines are generated using TALEN™ technology and offer opportunities to study signaling pathways and gene
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• Transfection Reagent
• Mirus Bio
• TransIT®-BrCa transfection reagent is a dedicated breast cancer cell-line specific reagent that can help researchers achieve high expression levels in breast cancer cell types including MCF-7, MDA-MB-231, MDA-MB-453, MDA-MB-468, and T47D. It c
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• Protein Proteolysis Mix
• Promega
• Trypsin/Lys-C mix is a combination of Trypsin Gold and rLys-C proteases. The mix increases peptide generation with in-solution protein digestion and can work with difficult-to-digest proteins. Enhanced proteolytic activity achieved through use of T
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• iPS Cell Lines
• Cellectis bioresearch
• The iPS Engineering Hub™ service can provide users with customized iPS cell lines engineered with TALEN™ technology. Donated somatic cells are reprogrammed by means of co-expressing four factors (Oct-4, SOX2, c-Myc, and Klf-4) by nonintegrating tec
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• Reporter Kits
• Horizon Discovery
• Available through a partnership with Promega, X-MAN™ reporter kits can enable researchers to apply cell-based assays that directly interrogate critical biological activities at endogenous expression levels. The X-MAN reporter kits are designed for
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• DNA Reference Standard
• Horizon Discovery
• The Quantitative Multiplex DNA reference standard is intended for researchers assessing multiple biomarkers in a single assay using platforms such as next-generation sequencing. It can enable researchers to quantify a range of detection thresholds