Related to Bioanalysis of Oligonucleotide Therapeutics

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• Retinoic Acid Assay Kits
• INDIGO Biosciences
• Retinoic acid receptor (RAR) gamma and retinoic-acid orphan receptor (ROR) gamma assay systems are now available in cell-based assay kits that enable researchers to obtain data in four steps: thaw, feed, dose, read. The RORγ and RARγ assay kits can
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• LC/MS/MS System
• Shimadzu Scientific Instruments
• Designed for trace quantitative work in complex matrices, the LCMS-8080 achieves a low femtogram-to-attogram range detection limit for various compounds with ion source and interface technologies, which can reduce chemical background. The LCMS-8080
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• LC-MS System
• Thermo Fisher Scientific
• The Exactive Plus system is a benchtop liquid chromatography-mass spectrometry (LC-MS) system for high-throughput screening, identification, and quantification of compounds in complex matrices. Powered by Orbitrap technology, the Exactive Plus syst
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• LC-MS Instrument
• Shimadzu Scientific Instruments
• The LCMS-8040 achieves high sensitivity by reengineering ion optics and collision cell technology, which can result in higher ion transmission and collision-induced dissociation efficiency. The LCMS-8040 can help scientists to conduct “Qual/Quan” a
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• Bioluminescent Enzyme
• Promega
• The NanoLuc™ luciferase can provide new capabilities in reporter assays with the potential to aid with biologically complex applications that require greater sensitivity. It is small in size, allowing for viral delivery and protein fusion applicati
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• Dried Blood-Spot Analysis
• Agilent Technologies
• The Automated Card Extraction LC/MS system, an integrated instrument for the analysis of dried blood spots and other dried media, works well for pharmaceutical and clinical research laboratories. Dried blood-spot analysis can be used to obtain quan
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• Immunoassay Slide
• QuantiScientifics
• The A²® Oligo-Link-it slide is designed for the development of multiplex immunoassays. The plastic slide contains arrays of capture oligonucleotides covalently linked to the surface. Antibodies can then be oligo-linked to complementary ol
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• Assay Plate
• PerkinElmer
• The 96-well cellular label-free assay plate for the EnSpire® label-free multimode plate reader platform is designed to support basic life science research as well as assay development applications. The plate requires no assays; each well of th
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• Microplate Stacker
• BioTek Instruments
• The BioStack3 microplate stacker features a dual-plate carrier and rotational wrist to move plates from the source stack to the instrument and back to the destination stack, keeping two plates in process. BioStack3 is designed to provide increased
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• Cell-Signaling Assays
• Bio-Rad
• Bio-Plex Pro cell-signaling assays are designed for detecting phosphorylated and total proteins involved in key intracellular signaling pathways. The 34 magnetic bead–based immunoassays (23 phosphoprotein and 11 total protein targets) have been ref
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• Fatty Acid Oxidation Reagent
• Seahorse Bioscience
• The XF Palmitate-BSA FAO Reagent, an aqueous solution that can be readily absorbed and utilized by cells, can help with fatty acid oxidation (FAO) assays and works well for use in cell-based XF FAO assays. This standardized, quality-controlled, rea
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• Capture Oligonucleotides
• Integrated DNA Technologies (IDT)
• xGen™ Lockdown™ probes are individually synthesized 60–120 nucleotide 5’-biotinylated capture oligonucleotides designed to enable high-depth sequencing and analysis of specific regions of the genome. xGen Lockdown probes work well for target enrich
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• Autoantibody Assay Kits
• Genalyte
• Assays for the Maverick™ detection system are now available. The Maverick ENA 4 and ENA 6 assay kits simultaneously screen for several common autoantibodies found in autoimmune connective tissue disorders, such as systemic lupus erythematosus. Thei
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• Nitrocellulose Membranes
• GE Healthcare Life Sciences
• The Whatman™ FF High Performance (HP) membrane is a diagnostic membrane that enables line separation and reproducible results for the detection of target molecules in liquids such as water, urine, blood, and saliva. The target molecules may include
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• Single-Cell Gene Expression Assay
• NanoString Technologies
• A single-cell gene expression application is now available that can provide researchers with a flexible and sensitive approach to discovering differences in cell-to-cell gene expression profiles. The nCounter® Single-Cell Gene Expression assay
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• Target Enrichment
• Roche
• Multiple new SeqCap EZ Library target enrichment products are now available. SeqCap EZ Exome Plus Library adds up to 50 Mb of custom targets to the existing 64 MB EZ Exome v3 products. SeqCap EZ Exome +UTR Library offers an exome enrichment design
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• Assay Reader Module
• Tecan
• The Infinite® F200 PRO multimode reader now features an AlphaScreen® module for AlphaScreen and AlphaLISA® assays. Offering sensitivity for screening and research, the new option works well for low- and medium-throughput applications
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• LC/MS Sample Filtration
• Agilent Technologies
• Captiva ND and ND Lipids filter plates and new 3 mL cartridges are designed to make particulate removal, protein precipitation, and lipid removal more user-friendly. The non-drip design can simplify workflows with in-well precipitation, reducing th
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• Sample Prep/LC System
• Thermo Fisher Scientific
• The Prelude SPLC sample preparation and liquid chromatography system was developed to make analysis of target compounds in complex biological matrices routine for clinical research and forensic toxicology laboratories. It is designed to enhance LC-
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• MS Syringe Filter
• Pall Life Sciences
• Acrodisc® MS is a syringe filter certified for low extractables in high-performance liquid chromatography/mass spectrometry applications. The 13 mm size is designed for small sample analysis and low extractable levels. MS syringe filters can r