Related to Enabling Tools Extend the Range of HCA

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• Data Analysis Software
• OriginLab
• Origin® and OriginPro® version 9 features enhanced 3D graphing using OpenGL, which boosts performance for plotting and editing 3D graphs created from large datasets. Users can rotate, pan, and zoom within 3D graphs to examine details. The
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• Shaker Software
• LabStrong
• The LabStrong Connect software allows for automation applications of the Helix 250 and is available as a free download. Users can use the software to set-up, run, and analyze results of experiments. LabStrong Connect allows users to control the Hel
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• Data Storage
• Agilent Technologies
• OpenLAB Data Store with Lab Applications is meant for smaller laboratories and provides central storage of the data produced by OpenLAB chromatography data systems. The software is also designed to streamline the management of laboratory operations
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• High-Content Imaging
• TTP LabTech
• The acumen® hci (high-content imaging) can image and analyze the whole wells of 96- to 1,536-well plates at a resolution of 0.5 µm/pixel. This enables the screening of high-density plates and can facilitate assay miniaturization. It also
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• Automated Workflow Scheduling Software
• Thermo Fisher Scientific
• Momentum 3.2 software for automation control can streamline sample submission and allow the execution of automated microtiter plate-handling processes with good user control and process management. It includes three user-level controls: Administrat
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• In Vivo Imaging
• PerkinElmer
• The IVIS Lumina series III benchtop imaging system integrates bioluminescence and full spectral fluorescence in in vivo imaging technologies. The platform can perform multiple modalities including photographic, bioluminescent, fluorescent imaging,
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• Transporter Knockout Cell Lines
• Sigma-Aldrich
• MDR1, BCRP, and MRP2 transporter knockout cell lines are now available that enable identification of substrate/transporter interactions without chemical inhibitors or knockdown RNAi technology. The knockout cell lines are available as assay-ready p
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• Microplate Detection Platform
• Molecular Devices
• The SpectraMax i3 platform’s base system features an integrated optical system enabling top and bottom reads for 6–384-well microplates and launches with three detection modes: luminescence, absorbance, and fluorescence. The user-exchangeable cartr
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• Incubator for Cell-Based Research
• Thermo Fisher Scientific
• The Cytomat® 10 is an automated incubator and storage module for high-capacity cell growth and assay incubation. It offers environmental control and can be integrated with existing automated assay hardware. A thermal disinfection method can ge
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• Image Analysis System
• Syngene
• The PXi Touch comes as a compact, ready-to-use unit with a built-in touch screen and processor. Each PXi Touch features a camera with a large fixed aperture lens, which enables scientists to capture images of faint bands or spots. The system is ava
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• Fluorescent Protein
• Allele Biotech
• mNeonGreen is a monomeric green fluorescent protein derived from the lancelet (cephalochordate) Branchiostoma lanceolatum . It has been demonstrated to perform as a fusion tag to a large number of target proteins when expressed in mammalian cells.
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• CCD Cameras
• Quantum Scientific Imaging
• The QSI RS series features a range of full-frame and interline transfer CCDs from 768x512 pixels up to 8.3MP. Dual-read rates of up to 8 MHz with USB 2.0, deep cooling to greater than 45°C below ambient and 16-bit pixel depth allow QSI RS seri
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• Nanoparticle Viewing Unit
• NanoSight
• The NS300 utilizes particle characterization technology and can visualize and measure particles in suspension in terms of size, light scattering intensity, fluorescence, and count. It does so particle-by-particle in the range 10–1,000 nm (material
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• In Vivo Imaging Agent
• PerkinElmer
• The GFR-Vivo™ 680 imaging agent allows researchers to measure glomerular filtration rate noninvasively, in vivo in animals. GFR-Vivo 680, in combination with fluorescence molecular tomography imaging, can provide a noninvasive approach to generate
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• Hematopoietic Colony Imaging System
• STEMCELL Technologies
• STEMvision™ is a bench-top instrument and computer system designed specifically for automated imaging and counting of hematopoietic colonies in the colony-forming unit assay. This system is meant to be used with MethoCult™ media and meniscus-free S
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• Image Acquisition and Analysis Software
• Molecular Devices
• MetaXpress® 5.0 high-content image acquisition and analysis software has been designed to improve the ease and speed of custom analysis using ImageXpress® Micro and Ultra systems. The new software enables user-created analysis to be run o
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• Microscopy Automation and Image Analysis Software
• Molecular Devices
• Version 2.5 of the MetaMorph® NX microscopy automation and image analysis software now includes modules for the study of neuronal morphology and fiber structures, support for targeted illumination devices, and a high-speed image acquisition mo
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• Correlated Microscopy Image Software
• FEI
• MAPS is modular automated processing system software for researchers who need to capture high-resolution data. MAPS software uses only image data to correlate and is compatible with any light microscope. Features in light microscopy images are used
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• Image Analysis Software
• PerkinElmer
• inForm® image analysis software is an automated image analysis package for quantifying biomarker expression in tumors and surrounding tissues. The software program is available in two packages: inForm Tissue Finder™ and inForm Cell Analysis™.
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• Cell Imaging System
• GE Healthcare Life Sciences
• The IN Cell Analyzer 2200 is a modular imaging system suitable for both investigative microscopy and automated high-content screening of organelles, cells, tissues, and whole organisms. The flexibility of the analyzer enables the system to be used