Related to Domainex to Provide Sigma-Aldrich with Expertise to Enable Study of Epigenetic Proteins

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• Microplate Washer
• BioTek Instruments
• The 405™ Touch microplate washer features a high-resolution, LED-backlit touchscreen interface that aids in protocol creation and implementation as well as instrument maintenance, and supports all gloved environments. Additionally, it includes two
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• Retinoic Acid Assay Kits
• INDIGO Biosciences
• Retinoic acid receptor (RAR) gamma and retinoic-acid orphan receptor (ROR) gamma assay systems are now available in cell-based assay kits that enable researchers to obtain data in four steps: thaw, feed, dose, read. The RORγ and RARγ assay kits can
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• Rat Transgene Integration
• Sigma-Aldrich
• The CompoZr® Targeted Integration Kit-rRosa26 integrates transgenes into the Rosa26 safe harbor locus in the rat genome. CompoZr targeted integration kits employ CompoZr zinc finger nucleases (ZFNs) for precise and heritable gene knock-in, ena
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• Bioluminescent Enzyme
• Promega
• The NanoLuc™ luciferase can provide new capabilities in reporter assays with the potential to aid with biologically complex applications that require greater sensitivity. It is small in size, allowing for viral delivery and protein fusion applicati
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• Assay Plate
• PerkinElmer
• The 96-well cellular label-free assay plate for the EnSpire® label-free multimode plate reader platform is designed to support basic life science research as well as assay development applications. The plate requires no assays; each well of th
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• Microplate Stacker
• BioTek Instruments
• The BioStack3 microplate stacker features a dual-plate carrier and rotational wrist to move plates from the source stack to the instrument and back to the destination stack, keeping two plates in process. BioStack3 is designed to provide increased
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• Cell-Signaling Assays
• Bio-Rad
• Bio-Plex Pro cell-signaling assays are designed for detecting phosphorylated and total proteins involved in key intracellular signaling pathways. The 34 magnetic bead–based immunoassays (23 phosphoprotein and 11 total protein targets) have been ref
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• Fatty Acid Oxidation Reagent
• Seahorse Bioscience
• The XF Palmitate-BSA FAO Reagent, an aqueous solution that can be readily absorbed and utilized by cells, can help with fatty acid oxidation (FAO) assays and works well for use in cell-based XF FAO assays. This standardized, quality-controlled, rea
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• Autoantibody Assay Kits
• Genalyte
• Assays for the Maverick™ detection system are now available. The Maverick ENA 4 and ENA 6 assay kits simultaneously screen for several common autoantibodies found in autoimmune connective tissue disorders, such as systemic lupus erythematosus. Thei
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• Nitrocellulose Membranes
• GE Healthcare Life Sciences
• The Whatman™ FF High Performance (HP) membrane is a diagnostic membrane that enables line separation and reproducible results for the detection of target molecules in liquids such as water, urine, blood, and saliva. The target molecules may include
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• Epigenetics Conjugates
• Cisbio Bioassays
• The epigenetics toolbox is a selection of conjugates specifically developed for epigenetics studies to help pharmaceutical and biotechnology researchers better understand how these events occur through epigenetic mechanisms and how they relate
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• Single-Cell Gene Expression Assay
• NanoString Technologies
• A single-cell gene expression application is now available that can provide researchers with a flexible and sensitive approach to discovering differences in cell-to-cell gene expression profiles. The nCounter® Single-Cell Gene Expression assay
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• Methylated Gene Targeting
• Cellectis bioresearch
• TALEN™ CpG™ is a service designed to overcome the impact of methylated DNA on TALEN nuclease activity. Users can target any gene at any position in any cell type regardless of methylation status. The service can make gene editing accessible for the
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• Target Enrichment
• Roche
• Multiple new SeqCap EZ Library target enrichment products are now available. SeqCap EZ Exome Plus Library adds up to 50 Mb of custom targets to the existing 64 MB EZ Exome v3 products. SeqCap EZ Exome +UTR Library offers an exome enrichment design
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• Assay Reader Module
• Tecan
• The Infinite® F200 PRO multimode reader now features an AlphaScreen® module for AlphaScreen and AlphaLISA® assays. Offering sensitivity for screening and research, the new option works well for low- and medium-throughput applications
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• Transporter Knockout Cell Lines
• Sigma-Aldrich
• MDR1, BCRP, and MRP2 transporter knockout cell lines are now available that enable identification of substrate/transporter interactions without chemical inhibitors or knockdown RNAi technology. The knockout cell lines are available as assay-ready p
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• microRNA Inhibitors
• Sigma-Aldrich
• Each Mission® synthetic and lentiviral microRNA inhibitor is designed for the long-term suppression of any miRNA endogenous to humans or mice, using an algorithm that evaluates all possible sequences for the design predicted to best maintain t