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Related to Analyzing Oligos from Biological Matrices

    • Capture Oligonucleotides
    • Integrated DNA Technologies (IDT)
    • xGen™ Lockdown™ probes are individually synthesized 60–120 nucleotide 5’-biotinylated capture oligonucleotides designed to enable high-depth sequencing and analysis of specific regions of the genome. xGen Lockdown probes work well for target enrich
    • SPE Tube Holders
    • Phenomenex
    • Two new Tabless Tube Holder accessories for the Strata® and Strata™-X lines of silica-based and polymeric solid phase extraction (SPE) sorbents are available. These accessories hold SPE tubes in 96-well spacing to integrate with automated syst
    • Chromatography Media
    • GE Healthcare Life Sciences
    • Ni Sepharose™ excel is an immobilized metal ion affinity chromatography medium (resin) for the direct capture and purification of secreted histidine-tagged recombinant proteins from eukaryotic cell culture supernatants. The new resin can reduce sam
    • Separation Columns
    • Biotage
    • Universal Phase Separators are fitted with a selectively permeable insert that separates aqueous phases from organic solvents under gravity; this can help remove an upper organic phase from a lower aqueous phase during a traditional liquid-liquid e
    • Chromatography Media
    • Asahi Kasei Bioprocess
    • TechniPur™ 40 μm ion exchange (IEX) chromatography media feature next-generation rigid agarose beads for biomolecule purification. TechniPur can reduce nonspecific interactions and provide greater capacity coupled with good mass transfer. In additi
    • Anion Chromatography Sorbent
    • Pall Life Sciences
    • The HyperCel™ STAR AX is a high-capacity anion exchange chromatography sorbent designed for high-salt solutions. Users can capture target protein directly from feedstock at conductivities of up to 15 mS/cm—no unit operations of ultrafiltration/difi
    • 96-Well Plates
    • Reinnervate
    • The Alvetex® Scaffold 96-well plates allow scientists to grow tumor cells in a way that mimics the way these cells grow in vivo and test the cytotoxic effect of novel or existing anticancer compounds using standard cell health assays including
    • Peptide Chromatography Columns
    • Waters
    • Acquity UPLC® CSH130 C18 and XSelect™ HPLC CSH130 C18 columns allow for the analysis and purification of peptides and for the quality of information generated by UPLC, LC, and LC-MS assays. The synthesis process for the Charged Surface Hybrid
    • UHPLC Core-Shell Media
    • Phenomenex
    • The Kinetex 1.3-micron—the micron with the smallest diameter in the Kinetex family—features efficiency levels of over 400,000 plates per meter. While fully porous sub-2-micron columns can exhibit significant band broadening due to frictional heatin
    • High-Pressure Ion Chromatography System
    • Thermo Fisher Scientific
    • The Dionex ICS-5000+ Reagent-Free™ HPIC™ system is designed to operate at continuous pressures up to 5,000 psi at analytical flow rates while using high-pressure ion chromatography to standard bore and microbore as well as capillary format separati
    • Gas Chromatograph
    • Shimadzu Scientific Instruments
    • Based on the GC-2010 Plus and integrating a barrier discharge ionization detector, the Tracera gas chromatograph can reveal trace components not easily detected. Tracera provides analysis of organic compounds, permanent gases, and light hydrocarbon
    • His-Tagged Protein Purification
    • Roche
    • The cOmplete His-Tag purification resin is a high-capacity immobilized metal affinity chromatography matrix for convenient single-step purification of His-tagged protein. Compatibility with large amounts of EDTA and DTT allows optimization of buffe
    • Mitochondrial Toxicity Assays
    • INDIGO Biosciences
    • A new series of assays called the MitoVir platform evaluate mitochondrial toxicity by examining inhibition of the ribonucleoside triphosphates that are substrates for the human mitochondrial RNA polymerase (POLRMT). The MitoVir platform is based on
    • Kidney Toxicity Panels
    • Bio-Rad
    • Developed through a partnership with Myriad RBM, the Bio-Plex Pro RBM assays enable the detection of multiple biomarkers in a single sample, which may reveal damage within hours of kidney injury. This early detection can improve drug testing in bot
    • Reversed-Phase HPLC Column
    • Hamilton Company
    • The PRP-C18 reversed-phase HPLC column expands the pH range of reversed-phase chromatography, providing separations over an extended column life. Stability to pH extremes extends the application of reversed-phase chromatography to the separation of
    • Sample Prep/LC System
    • Thermo Fisher Scientific
    • The Prelude SPLC sample preparation and liquid chromatography system was developed to make analysis of target compounds in complex biological matrices routine for clinical research and forensic toxicology laboratories. It is designed to enhance LC-
    • MS Syringe Filter
    • Pall Life Sciences
    • Acrodisc® MS is a syringe filter certified for low extractables in high-performance liquid chromatography/mass spectrometry applications. The 13 mm size is designed for small sample analysis and low extractable levels. MS syringe filters can r
    • Chromatography Columns
    • Phenomenex
    • Yarra™ is a family of aqueous size-exclusion chromatography (SEC) columns for biomolecule analysis. Yarra columns are engineered to provide efficiency increases of up to 70% and higher resolving power. Yarra columns, offered in three phases with 3-
    • 10-Micron Chiral Media
    • Phenomenex
    • Lux™ Cellulose-1 and -2, complementary chiral stationary phases, are now available in 10-micron particle size for batch-preparative chromatography. The 10-micron particles are available both in Axia™-packed preparative columns, and in bulk, enablin
    • 5-Micron Core-Shell Media
    • Phenomenex
    • A 5-micron particle has been added to the Kinetex® core-shell product line. As the largest diameter particle in the family, Kinetex 5-micron core-shell columns can deliver better performance than 3- or 5-micron fully porous offerings, with no
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GEN Poll

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Genome Sequencing and Patient Autonomy

Do you think ACMG’s recent recommendations for reporting incidental clinical sequencing results undermine patient autonomy?

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