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Related to Unfulfilled Promise of Predictive Toxicology

    • Mitochondrial Toxicity Assays
    • INDIGO Biosciences
    • A new series of assays called the MitoVir platform evaluate mitochondrial toxicity by examining inhibition of the ribonucleoside triphosphates that are substrates for the human mitochondrial RNA polymerase (POLRMT). The MitoVir platform is based on
    • Kidney Toxicity Panels
    • Bio-Rad
    • Developed through a partnership with Myriad RBM, the Bio-Plex Pro RBM assays enable the detection of multiple biomarkers in a single sample, which may reveal damage within hours of kidney injury. This early detection can improve drug testing in bot
    • UHPLC Separation System
    • Thermo Fisher Scientific
    • The Dionex™ UltiMate™ 3000 biocompatible rapid separation system is designed to bring flexible UHPLC separation capabilities to a range of biopharmaceutical research and QA/QC analyses. The UltiMate 3000 BioRS system has a selection of modules that
    • Sample Prep/LC System
    • Thermo Fisher Scientific
    • The Prelude SPLC sample preparation and liquid chromatography system was developed to make analysis of target compounds in complex biological matrices routine for clinical research and forensic toxicology laboratories. It is designed to enhance LC-
    • Liquid Junction Kit for UHPLC
    • Thermo Fisher Scientific
    • A UHPLC liquid junction kit is now available for the Nanospray Flex ion source for electrospray ionization LC-MS. The new kit can extend the functionality of the source by elevating packed-tip column performance to UHPLC levels. The Nanospray Flex
    • Autosampler for Organic Volatiles
    • Thermo Fisher Scientific
    • The TriPlus 300 headspace autosampler has been designed for analyzing organic volatiles. This valve-and-loop headspace autosampler features a 120-vial sample tray capacity and 18-vial incubation oven overlap capacity, enabling unattended high-throu
    • High-Content Imaging Software
    • Thermo Fisher Scientific
    • HCS Studio software is a suite of high-content imaging and analysis applications offering researchers the ability to interact with and analyze cell images and corresponding data. The HCS Studio software features built-in intelligence and enhanced u
    • Bioprocess Container Film
    • Thermo Fisher Scientific
    • Aegis™ 5-14 premium film is used to manufacture Thermo Scientific™ bioprocess containers for biopharma drug discovery and production. Developed specifically for liquid handling, production, storage, and transportation, Aegis 5-14 is a five-layer, 1
    • LC-MS System
    • Thermo Fisher Scientific
    • The Orbitrap Fusion LC-MS combines its three mass analyzers—quadrupole, Orbitrap, and linear ion trap—in a “Tribrid” architecture that offers depth of analysis of complex biological samples. This Tribrid configuration allows users to identify large
    • Data Acquisition System
    • Molecular Devices
    • The Axon™ Digidata® 1550 low-noise data acquisition system allows for the parallel patching of up to eight cells simultaneously. It features eight independent analog output channels to simultaneously send command waveforms to multiple cells at
    • Triple-Stage Quadrupole LC/MS Systems
    • Thermo Fisher Scientific
    • Two triple-stage quadrupole LC/MS systems, the TSQ Quantiva and the TSQ Endura, enable the quantitation and confirmation of compounds in complex matrices. The TSQ Quantiva’s sensitivity is due to its use of active ion management (AIM), a technique
    • LC/MS Data Visualization Software
    • Thermo Fisher Scientific
    • FreeStyle™ 1.0 is a data visualization software for information rendering, method development, and data-quality assessment. It also provides report-writing capabilities. FreeStyle 1.0 is designed to be compatible with both low- and high-resolution
    • High-Content Imaging System
    • PerkinElmer
    • Live cell capabilities have been added to the Operetta system including brightfield imaging and environmental chamber options, as well as a transmitted light digital phase-contrast mode that can be used to image and segment live cells without using
    • PCR Reagents
    • Thermo Fisher Scientific
    • Phusion Green High-Fidelity DNA Polymerase and Luminaris Color qPCR master mixes utilize tracking dyes that are meant to speed up the pipetting process. By providing a visual confirmation, the mixes are designed to reduce the chance of human error
    • Benchtop NMR Spectrometer
    • Thermo Fisher Scientific
    • The picoSpin 80, a portable NMR spectrometer that has a magnet rated at 2 Tesla, is designed to operate at 82 MHz and measure high-resolution spectra. This benchtop-scale instrument’s other features include a fluid capillary system, which is contai
    • High-Content Imaging System
    • Molecular Devices
    • The ImageXpress® Micro XLS system can be used to carry out widefield, high-content screening in fixed-endpoint and time-lapse studies. With a screening capability of more than 50,000 wells per day, the system is designed to expedite the charac
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