Related to Targeted Genome Editing via ZFN Methodology

• 
• Rat Transgene Integration
• Sigma-Aldrich
• The CompoZr® Targeted Integration Kit-rRosa26 integrates transgenes into the Rosa26 safe harbor locus in the rat genome. CompoZr targeted integration kits employ CompoZr zinc finger nucleases (ZFNs) for precise and heritable gene knock-in, ena
• 
• Genome Mapping System
• BioNano Genomics
• The Irys™ is a genome mapping system that can help genomics researchers with structural variation analysis and sequence assemblies. Irys is an automated platform that uses single-molecule imaging to visualize extremely long nucleic acids and reveal
• 
• Genetic Analyzer
• Pacific Biosciences
• The PacBio® RS high-resolution genetic analyzer has undergone a software upgrade featuring additional tools for performing DNA base modification analysis and de novo genome assembly. With the release of the SMRT Analysis 1.3.3 software upgrade
• 
• Transporter Knockout Cell Lines
• Sigma-Aldrich
• MDR1, BCRP, and MRP2 transporter knockout cell lines are now available that enable identification of substrate/transporter interactions without chemical inhibitors or knockdown RNAi technology. The knockout cell lines are available as assay-ready p
• 
• microRNA Inhibitors
• Sigma-Aldrich
• Each Mission® synthetic and lentiviral microRNA inhibitor is designed for the long-term suppression of any miRNA endogenous to humans or mice, using an algorithm that evaluates all possible sequences for the design predicted to best maintain t
• 
• Genetic Variant Annotation Software
• BIOBASE Biological Databases
• Annovar® is a command-line tool that uses information to functionally annotate genetic variants from high-throughput sequencing data detected from different genomes (including human genome hg18, hg19, as well as mouse, worm, fly, yeast, and ot
• 
• Stabilized Pepsin
• SciGene
• CytoZyme™ stabilized pepsin is an advanced formulation for pretreating tissue samples in nucleic acid probe-based cytogenetic assays including FISH. CytoZyme is a ready-to-use solution of purified pepsin that can be stored in the refrigerator witho
• 
• Sequencing System
• Pacific Biosciences
• The PacBio RS II allows scientists to generate finished genome assemblies, reveal and understand epigenomes, and characterize genomic variation. Based on the SMRT sequencing technology, the RS II can generate average read lengths of 5,000 base pair