Related to ADC, BZL Aim Warheads at PSMA-Positive Prostate Cancers

• Women and Smoking
  Looking for a reason to quit, ladies? Look no further.
  
• Performing “Informative Clinical Trials” in Mice
  Patient-derived tumor xenografts: better than cancer cell lines for preclinical testing in animal models?
  
• Cancer Model Database Emerges from WOMB
  Oncology researchers wishing for a tool to help them find available models and services may have had their prayers answered.
  
• Literature Review: Which Drug Combination Will Unlock Triple-Negative Breast Cancer?
  Researchers describe a strategy for treating TNBC that combines noncompetitive antibodies to achieve degradation of EGFR and tumor inhibition.
  
• Detecting Acquired Drug Resistance in Cancer
  New methods allow noninvasive analysis in blood plasma.
  
• The Tumor Microenvironment as a Drug Target: Chasing Slippery Targets
  This first part of a two-part series discusses how researchers are looking at ways to attack tumors by targeting the cellular frameworks that keep them alive.
  
• The Tumor Microenvironment as a Drug Target, Part II
  In the search for new targets, cancer researchers are taking a closer look at the cellular support networks that allow tumors to survive.
  
• Literature Review: A Step Closer to Personalized Medicine
  Researchers use patient-specific cell lines derived in mice to personalize chemotherapy.
  
• Moving Genomics Closer to the Clinic
  Foundation Medicine and Memorial Sloan-Kettering Cancer Center are working to translate genomic information into personalized cancer treatment.
  
• Cancer’s Bitter Medicine
  CML experts raise industry hackles by decrying high-and-rising cost of treatments.
  
• Targeting Deranged Metabolism to Treat Cancer
  Scientists are investigating how genes controlling metabolism are connected with cancers.
  
• Editor’s Note: Myriad, the Supreme Court, and Gene Patents
  GEN's John Sterling weighs in.
  
• Eye on Single-Cell Analysis
  This in-depth look at single-cell analysis focuses on circulating tumor cell analysis and utility as a paradigm for the SCA space.
  
• Parsing the Phenome
  Using metabolic phenotyping approaches, researchers are deconstructing gene-environment interactions and their contributions to disease risk at the personal and population scales.
  
• Drug Candidates on Trial
  A list of recent clinical trials for drugs in development.
  
• New Gene Patent Suit Sparks Talk of Trolls
  The BRACAnalysis developer is poised to spawn a Myriad of lawsuits.
  
• Improving Preclinical Research
  The surest way to bring new drugs to market is also the most obvious—making certain they work before they reach the clinic.
  
• Opinion: A Stem of Hope for Cancer Treatments
  Evidence mounts in favor of therapies targeting cancer stem cells.
  
• Antibody-Drug Conjugates to Fight Cancer
  While mAbs have been extremely successful, these empowered antibodies are touted as the next big blockbusters.
  
• Does Clinical Success Mean Commercial Success for Cancer Vaccines?
  Getting insurers to pay for immunotherapies and keeping doctors more informed are key to market growth.