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The GENcast NETWORK ALERT


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PODCAST: "Novel Method for Detecting Reactive Oxygen Species"

—Niren Murthy, Ph.D., Principal Investigator, Laboratory for Biomaterials and Molecular Imaging, and Assistant Professor in the Wallace H. Coulter Department of Biomedical Engineering at Georgia Tech and Emory University, is interviewed by GEN's Editor in Chief, John Sterling.

WHEN: January 8 – January 15, 2009

Researchers have created a new family of fluorescent probes called hydrocyanines that can be used to detect and measure the presence of reactive oxygen species. These species are highly reactive metabolites of oxygen, which have been implicated in a variety of inflammatory diseases including cancer and atherosclerosis.

Details of the hydrocyanine synthesis process and experimental results showing the ability of the dyes to detect reactive oxygen species in cells, tissues, and mouse models were reported on December 8 in the online version of Angewandte Chemie International Edition. This research is supported by the NIH and the NSF.

During this week’s podcast, Dr. Niren Murthy explains how his team created the new family of hydrocyanines and what is so special about them. He also discusses the specific advantages these hydrocyanine dyes possess over those currently being used to image reactive oxygen species. Dr. Murthy describes the types of experiments that took place to test the ability of the dyes to detect reactive oxygen species inside cells and animals and lists the results that were achieved.

He also talks about specific applications for these novel probes and reveals the next phase of research his group has planned based on these initial studies.

LISTEN NOW to this week's GEN podcast.

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Genetic Engineering & Biotechnology News is the most widely read publication in the biotechnology industry and the only high-frequency publication focused on international bioindustry news. Established in 1981, GEN is also the first biotechnology trade publication, having covered the industry since its inception.

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