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GEN News Highlights : Apr 21, 2009

Merck & Co. Acquires Rights to C. Difficile Drugs from Medarex and MBL for $60M

Organizations may receive $165 million in development milestones.

Medarex and Massachusetts Biologic Laboratories (MBL) have out-licensed to Merck & Co. an antibody combination that targets C. difficile in a deal worth over $225 million. Merck gains the worldwide rights to market and further develop the CDA-1 and CDB-1 antibody combination and will pay Medarex and MBL $60 million up front.

A further $165 million will be paid upon the completion of certain milestones. Medarex and MBL will recieve double-digit royalties and milestones if certain sales levels are met. Pursuant to a prior co-development agreement, Medarex and MBL will divide all payments equally.

A Phase II multicenter, randomized, double-blind trial showed a reduction in the incidence of infection among 200 patients when compared to those taking a placebo, says Merck. An oral presentation of the results is slated for June 2 at Digestive Disease Week.ADNFCR-2184-ID-19131120-ADNFCR