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GEN News Highlights : Jan 8, 2007

Catalyst and Wyeth Ink Agreements Worth Up To $100M

Deals support discovery and preclinical development of a metabolic disease and an oncology target.

Catalyst Biosciences signed two agreements with Wyeth Pharmaceuticals with potential payments of up to $100 million plus royalties. The research collaboration and license agreements support discovery and preclinical development using Catalyst's Alteraseā„¢ therapeutics platform (engineered human proteases) directed at a target in metabolic disease and one in oncology.

Wyeth will be responsible for the clinical development, manufacturing, and marketing of products developed as a result of these collaborations. The deal includes an upfront license payments, milestone payments, R&D funding, and royalties on product sales.