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Insight & Intelligence™ : Apr 29, 2014

The Utility of Fat for Regenerative Medicine

The adipose tissue field is translating from plastic surgery to possible regenerative purposes.
  • Enal Razvi, Ph.D.

This report represents our continuing coverage of the potential utilization of adipose tissue and its associated components (such as the stem cells contained therein) as a means for mediating regenerative medicine.

Highlights of this report:

  • The current use of fat for cosmetic and reconstructive purposes provides the raison d’être for its deployment for regenerative medicine/cellular therapy.
  • More work remains to identify the component[s] within adipose tissue responsible for its regenerative properties—Is it the cells? The scaffold? The cytokine milieu? Much is unclear at present.
  • These results lend credibility to the notion that early clinical results could provide a good rationale for deeper investigations for mechanism of action; the case here demonstrates that clinicians utilizing adipose-derived cells as a means for addressing musculoskeletal and other conditions provide a good foundation for exploring the regenerative potential of this tissue.