The focus of this GEN Market & Tech Analysis report is to present some of our recent industry tracking of the microRNA publications ensemble as a means to describe hotspots of microRNA association with biological phenotypes both spatially and temporally.

We’ve harvested the entire set of publications where microRNAs are mentioned in the title and/or abstract, and this served as the starting material for algorithms to sort them based on their association into specific space. Not only did we generate the hotspot map but also we examined the following:

The evolution of the hotspot map over a two-year period
Temporal picture, i.e., how the associations “rolled out” over time

This analysis provides a means for segmenting associations of microRNAs with specific physiological/pathological states and also allows us to examine the “research trends” associated with a given set of microRNAs.

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Enal Razvi, Ph.D., conducted his doctoral work on viral immunology and subsequent to receiving his Ph.D. went on to the Rockefeller University in New York to serve as Aaron Diamond Post-doctoral fellow under Professor Ralph Steinman [Nobel Prize Winner in 2011 for his discovery of dendritic cells in the early-70s with Zanvil Cohn]. Subsequently, Dr. Razvi completed his research fellowship at Harvard Medical School. For the last two decades Dr. Razvi has worked with small and large companies and consulted for more than 100 clients worldwide. He currently serves as Biotechnology Analyst and Managing Director of SelectBio U.S. He can be reached at enal@selectbio.us.

Gary M. Oosta holds a Ph.D. in Biophysics from Massachusetts Institute of Technology and a B.A. in Chemistry from E. Mich. Univ. He has 25 years of industrial research experience in various technology areas including medical diagnostics, thin-layer coating, bio-effects of electromagnetic radiation, and blood coagulation. Dr. Oosta has authored 20 technical publications and is an inventor on 77 patents worldwide. In addition, he has managed research groups that were responsible for many other patented innovations. Dr. Oosta has a long-standing interest in using patents and publications as strategic technology indicators for future technology selection and new product development.

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Eye on MicroRNA Associations and Signatures

The authors harvested the entire set of publications where microRNAs are mentioned in the title and/or abstract. Find out what they've learned.