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Bioprocessing Perspectives : May 1, 2014 ( )
Rapid Microbiology Testing
Getting to Pathogens before They Get to You!--h2>
Adventitious microorganisms—the bane of bioprocessing—may mingle with raw ingredients, light upon exterior surfaces, or settle into bioreactors. To deal with such organisms, bioprocessors need to understand them, the better to deter such unwelcome guests, avoiding all the problems associated with microbiological contamination.
BioLumix is unsuitable for sterile injectable products, whose purity is guaranteed by kill steps involving heat or chemicals (and sterilizing filtration) and confirmed post-production through lengthy culture-based assays. Rather, its strength lies in testing of raw materials and laboratory or process area surfaces.
Like the Biolumix system, many rapid tests employ indicators of viable and actively multiplying organisms.
Can You Cheat with MALDI?
All rapid microbiology tests require some level of enrichment of target pathogens or surrogate molecules, and all tests must somehow match practical sample size and pathogen concentration with the test’s physical and detection capabilities.
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