Oct 1, 2011
(Vol. 31, No. 17)
Defining the Future of Biomanufacturing
Xcellerex is revolutionizing the way biomolecules are developed, manufactured, and commercialized. The company’s unique single-use technology platform transforms biomanufacturing economics, enabling the development of biotherapeutics and vaccines, and dramatically improving the ability of Xcellerex and its partners to deploy manufacturing capacity.
Xcellerex is a technology and equipment company, but our roots are in designing and running biomanufacturing operations. As a result, we structured the company to include a unique blend of expertise and services that we know to be essential to smoothing our clients’ pathway to new biomanufacturing capacity.
To date, more than 20 therapeutic proteins and vaccines have been manufactured for clinical trials using Xcellerex technology.
Xcellerex Equipment Platform
Xcellerex offers FlexFactory controlled environmental modules, as well as a line of single-use bioreactors and mixers that have become the standard in the bioprocess industry. Our XDR single-use bioreactors are fully integrated stirred-tank systems that deliver the performance and scaleability of stainless steel systems with the convenience and quality of single-use technology.
XDR reactors are fully characterized and feature a process modeling database that enables instantly optimized process scale-up or tech transfer. XDR systems are available with working volumes ranging from 4 L to 2,000 L. Xcellerex also offers XDM Quad Mixers and a full complement of related single-use assemblies.
FlexFactory Services Platform
Xcellerex supports its equipment and platform with a unique portfolio of services. From process design and optimization to facility design to process equipment integration, Xcellerex can help ease the transition to single-use technologies. Through its TransPlantSM services, Xcellerex can “bridge” manufacture a partner’s biomolecule at our GMP facility while the partner’s FlexFactory is constructed, validated, and TransPlanted to the partner’s site. This unique model both accelerates time to clinical and commercial manufacturing and allows partners to manage the development and market risk of adding manufacturing capacity.
Xcellerex is uniquely positioned to help biotech companies produce drugs for clinical or commercial use with the same speed and convenience as a conventional CMO, while also helping the client establish the knowledge and infrastructure required to control its long-term destiny.
Integration and Process Know-How
Xcellerex is unique among equipment manufacturers in that we offer years of biomanufacturing operations experience and we use our equipment every day. Our team’s experience in designing processes, integrating hardware and software, and designing optimized single-use facilities enables us to help our customers streamline their road to new capacity, while avoiding many of the first-time mistakes that lurk around every corner. More than our innovative equipment design and services offerings, it is this hands-on knowledge that our current customers value most in our partnerships.