Biotechnology from bench to business

• Follow GEN on:
• Login | Register | Subscribe

• ADME/Tox
• Automation
• Bioprocess Scale-Up
• Bioreactors
• Biosimilars
• Cell Culture
• Cell-Based Assays
• Contract Manufacturing
• Gene Therapy
• High-Throughput Screening
• Immunoassay
• Induced Pluripotent Stem Cells
• Informatics
• Liquid Handling
• mAb Production
• Protein Characterization
• Protein Detection
• Protein Production
• Regenerative Medicine
• RNAi/siRNA
• Stem Cells
• Western Blot

• GEN Articles

• More »

• Feature Articles: Harnessing the Power of Kinase Inhibitors
  
• Feature Articles: Kinase Assays Find Niche in Cancer Drug R&D
  
• Feature Articles: R&D in the Protein Kinase Field Blossoms
  With Over 500 Inhibitors in Various Stages of Development, Effective Assays Are Critical
• Tutorials: Predicting Drug-Induced Myelotoxicity
  CFC Assays Using Primary Bone Marrow Cells Show Utility in Toxicity Screening
• Tech Notes: Developments in Focused Kinase Libraries
  Research Using Smaller Collections Reported to Shorten Discovery Efforts

• Insight & Intelligence™

• More »

• A Faster KAYAK: Mass Spectroscopy for Multiplexed Kinase Assays
  October 29, 2012
  Researchers developed a new, simplified method for measuring the phosphorylation rates of peptide substrates.
• Inhibitors That Put A Kink in Abl's Helix
  September 28, 2012
  Researchers develop a direct-binding assay that enables the detection of allosteric inhibitors, which can suppress a cellular enzyme that contributes to leukemia.
• Protein Kinase Inhibitors for CNS Diseases at the Research and Discovery Phase
  June 1, 2011
  One company has a clinical candidate, but focus for now is to understand kinase involvement in neurodegenerative pathways.

• GEN News Highlights

• More »

• Horizon, AstraZeneca Seek Kinase-Targeting Cancer Drugs
  
• AstraZeneca, BIND Enter $200M+ Cancer Nanomedicine Agreement
  
• ArQule Regains Rights to AKT Inhibitor from Daiichi Sankyo
  
• Blueprint Medicines Collaboration Zeroes In on Cancer Targets
  
• Astellas and Ambit End Leukemia Drug Partnership
  

• New Products

• More »

Cisbio Bioassays Cell-Based Kinase Assays Three kinase assays are now available as part of a cell-based kinase screening platform. Phospho-STAT3 (signal transducer and activator of transcription 3) (Tyr705), Phospho-p38 MAPK (Thr180/Tyr182), and Phospho-IKKβ (Ser177/Ser181) involve targets

• Best Of The Web

• More »

• MAP Kinase Resource