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Gene Editing - Related Content
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  • CRISPR Madness
    November 8, 2013

    Scientists are working out the kinks of this breakthrough technology.
  • Gene Editing Typos
    October 8, 2013

    Researchers use a human cell-based reporter assay to characterize off-target cleavage of CRISPR-associated (Cas)9-based RNA-guided nucleases.
  • CRISPR/Cas Comes of Age—Almost
    July 25, 2013

    Genetic tools based on components of a bacterial adaptive immune system may offer a set of novel tools for adding, deleting, or replacing specific genes in model organisms.
  • Gene Editing to Treat Genetic Diseases, Part II
    June 25, 2013

    This second part of a two-part article on treating Duchenne muscular dystrophy discusses TALENs and TAL effectors as possible treatments.
  • Gene Editing with Multiple Molecular Means
    June 13, 2013

    This first part of a two-part article on treating Duchenne muscular dystrophy focuses on a potential new treatment that interferes with nonsense mutations.

Sigma-Aldrich

CRISPR/Cas Gene-Editing Tools

Sigma CRISPR/Cas technology consists of clustered, regularly interspaced, short palindromic repeat (CRISPR) RNA-guided nuclease complexes and an online design tool. The CRISPR nuclease complexes, which are packaged in single plasmid vectors contain

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