| November 15, 2009 (Vol. 29, No. 20) |
|
Pooled Genome-Wide shRNA Screening
Heather Holemon, Ph.D. Victoria Rusakova
|
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Transfection Market Clamors for Silver Bullet
Jonathan Witonsky
|
|
NBS Experiences Post-Acquisition Growth
Carol Potera
|
|
Oklahoma Seeks to Retain Local Research
Gail Dutton
|
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Making the Most of Transfection Processes
Catherine Shaffer
|
|
Head Start Boosts Value of Stability Testing
Vicki Glaser
|
|
"Simplexity" of Flow Cytometry Technology
J.C. Mason, Ph.D.
|
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Taking Multiplexing to the Next Level
K. John Morrow Jr., Ph.D.
|
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Strategies for Companies Targeting GPCRs
James Netterwald, Ph.D.
|
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Flow Cytometry's Expanding Niche
Richard A. Stein, M.D., Ph.D.
|
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Improving and Enhancing the Use of Quantitative PCR
Kathy Liszewski
|
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Sidebar: Industry Experts Share Flow Cytometry Insights
|
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Cracking Down on Misinformation
Bruce F. Mackler, Ph.D., J.D.
|
|
Developments in Focused Kinase Libraries
Richard Hill, Ph.D.
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|
Analytical Considerations in Formulation
Sian Estdale, Ph.D.
|
|
Dried Blood Spots for Toxicokinetic Studies
James C. Robbins, Ph.D. Lee Goodwin, Ph.D. Phillip Turpin, Ph.D.
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|
| November 1, 2009 (Vol. 29, No. 19) |
|
Cellular-Signaling Pathway Signatures
Wendy Weatherford Alexander Karasyov, Ph.D. James Schwaber, Ph.D. Frauke Rininsland, Ph.D.
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Sparing Patients the Needle Remains a Priority
Bruce Carlson
|
|
Senesco Attempts to Exploit Cell Death
Carol Potera
|
|
Lilly Unveils Green Biotechnology Campus
Vicki Glaser
|
|
Search Intensifies for Diabetes Drugs
Nina Flanagan
|
|
Single-Use Systems Make Headway with Skeptics
Angelo DePalma, Ph.D.
|
|
Sample Prep Advances Extend Mass Spec
K. John Morrow Jr., Ph.D.
|
|
New Capabilities Fortify Biodefense Tools
Gail Dutton
|
|
Animal Imaging Transforms Development
Elizabeth Lipp
|
|
Third Option for Stem Cell Research Emerges
Kenneth C. Aldrich
|
|
Certainty Not Required for Inventorship
William L. Warren S.Alex Cao, Ph.D.
|
|
Preserving the Integrity of Statistics
Zachary N. Russ
|
|
GEN's GREENbiopharma Conference Focuses on the Economic Rationales of Going Green in Biotech
|
|
Dual Scan Multiple Reaction Monitoring MS
Joanne Mather Paul D. Rainville Robert S. Plumb, Ph.D.
|
|
Applying Real-Time PCR to Strain Identification
Arun Apte
|
|
Using ClonePix FL to Assess Monoclonality
Julian F. Burke, Ph.D. Christopher J. Mann, Ph.D. Sky Jiang Kerensa J. Klottrup, Ph.D. Natalie Smithers, Ph.D. Omee Ahmed
|
|
Shaken Bioreactors Provide Culture Alternative
Tibor Anderlei, Ph.D. Christoph Cesana Cedric Bürki Maria De Jesus, Ph.D. Markus Kühner Florian Wurm Rene Lohser
|
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Gains Steadily Building in Biotech Sector
G.Steven Burrill
|
|
| October 15, 2009 (Vol. 29, No. 18) |
|
High-Resolution Melt Analysis Applications
Viresh Patel, Ph.D.
|
|
Firms Seek to Prove Cancer Stem Cell Hypothesis
Keith A. Markey, Ph.D.
|
|
Merrion Strives to Turn IV Drugs into Tablets
Carol Potera
|
|
High-Content Screening Surges Ahead
Vicki Glaser
|
|
Stem Cell Technologies Boost Regenerative Medicine
James Netterwald, Ph.D.
|
|
Enhancement of Cell Culture Techniques
Angelo DePalma, Ph.D.
|
|
Use of Microarrays Increasing Rapidly
Sophia Fox
|
|
qPCR Faces Growing Pains Head-On
Kathy Liszewski
|
|
Novel Tools Streamline Purification Process
K. John Morrow Jr., Ph.D.
|
|
Fighting Pancreatic Cancer's Intractable Nature
Patricia F. Dimond, Ph.D.
|
|
GEN's Cryptogram Challenge Solved
|
|
DTC Genomics & Leading-Edge Ethics
Chris MacDonald, Ph.D.
|
|
Cells That Get No Respect
|
|
Update on Evolving Regulatory Guidance
Bruce F. Mackler, Ph.D., J.D.
|
|
Assessment of Drug Interaction Potential
Igor Mezine, Ph.D. Chris Bode, Ph.D. Sid Bhoopathy, Ph.D.
|
|
Automated Cell Culture with 3-D Substrate
Nadia A. Badr Brad Justice Robin A. Felder, Ph.D.
|
|
Simulated Moving Bed Chromatography
Anthony Grabski, Ph.D. Robert Mierendorf, Ph.D.
|
|
| October 1, 2009 (Vol. 29, No. 17) |
|
Studying the S-Glutathionylation of Proteins
Thomas G. Brock, Ph.D. Micah Doty
|
|
Biosimilar Market Fails to Meet Projections
Bruce Carlson
|
|
Novasep Morphs Into Full-Service Company
Sophia Fox
|
|
Hong Kong Sees Opportunities with TCMs
Robert Yuan, Ph.D.
|
|
Advances in Quantitative Proteomics
Patricia F. Dimond, Ph.D.
|
|
Contract Manufacturing Demand Remains Strong
Cindy Liu William Downey
|
|
Novel Approaches Simplify Sample Prep
Elizabeth Lipp
|
|
Protein Expression Poised for Reinvention
K. John Morrow Jr., Ph.D.
|
|
Venture Philanthropy Bets on Risky Projects
Jonathan Simons, M.D.
|
|
Laskers Honor Stem Cell & Cancer Research
|
|
New Assays Invigorate Biomarker Discovery
Catherine Shaffer
|
|
Written Descriptions: How Much Is Enough?
Courtenay C. Brinckerhoff
|
|
Economic Realities of Clusters
Michael Sable, Ph.D.
|
|
Optimizing CHO Cell Culture Conditions
Christopher A. Sellick, Ph.D. Arfa R. Maqsood Alexandra S. Croxford, Ph.D. Alan J. Dickson, Ph.D. Royston Goodacre, Ph.D. Gill M. Stephens, Ph.D.
|
|
Cell-Counting Technologies Are Evolving
Clare Rogers Erin Gatza, Ph.D.
|
|
Trials and Tribulations for Melanoma Drugs
Simos Simeonidis, Ph.D.
|
|
| September 15, 2009 (Vol. 29, No. 16) |
|
Live-Cell Luminescent Assays for GPCR Studies
Brock F. Binkowski, Ph.D. Frank Fan, Ph.D. Keith V. Wood, Ph.D.
|
|
Tests to Rapidly Diagnose Sepsis Essential
Aruna Rajan Harry Glorikian
|
|
Symyx Technologies Ventures Into Novel Arena
Carol Potera
|
|
Karolinska Development Spins Off New Group
Sophia Fox
|
|
In Defense of Virtual Development Models
Greg Dombal Lauren Sherman
|
|
3-D Cell Culture for Discovery & Bioprocess
Nina Flanagan
|
|
HPLC Advances for Biomolecular Analysis
Susan Aldridge, Ph.D.
|
|
Research Reveals the Influence of miRNA
Kathy Liszewski
|
|
Strategies for Successful Formulation
Angelo DePalma, Ph.D.
|
|
Vaccine Production Shifts to High Gear
Vicki Glaser
|
|
Metabolic Profiling Crucial to Unveiling Cellular Complexity
Richard A. Stein, M.D., Ph.D.
|
|
Quebec Eyes Biotech as Key Growth Sector
Vicki Glaser
|
|
3-D Cerebral Cortex Model
|
|
Agency Gains Regulatory Clout
Bruce F. Mackler, Ph.D., J.D.
|
|
Parvovirus B19 VLP Vaccine Manufacturing
Daniel A. Shelly, Ph.D. Victor Van Cleave, Ph.D.
|
|
Deciphering the Process of Gene Evolution
|
|
Stability Testing for Protein Therapeutics
David Gregson, Ph.D. Lindsay Cole, Ph.D.
|
|
Reproducible Dispensing of Live Cells
Sini Suomalainen
|
|
| September 1, 2009 (Vol. 29, No. 15) |
|
Sample Enrichment Technology Advances
Clotilde Teiling Thomas Jarvie, Ph.D.
|
|
Access to Global Populations Speeds Trials
Douglas Peddicord, Ph.D.
|
|
EcoBiotics Scours Rainforest for Compounds
Carol Potera
|
|
Live-Cell Imaging Increases Impact on R&D
Gail Dutton
|
|
Innovation Marks Steady Growth of Asian Biotech
Gail Dutton
|
|
Peptide Therapies Coming Into Their Own
James Netterwald, Ph.D.
|
|
Next-Gen Sequencing Becoming Ubiquitous
Catherine Shaffer
|
|
Next-Gen Presents Array of Opportunities
Elizabeth Lipp
|
|
Streamlining Protein Sample Preparation
K. John Morrow Jr., Ph.D.
|
|
Bioprocess Monitoring Relies on Connectivity
Angelo DePalma, Ph.D.
|
|
Q&A on Sartorius Stedim Biotech/SAFC Deal
|
|
Searching for Appropriate Cancer Biomarkers
Amnon Gonenne, Ph.D.
|
|
Changing the Face of Clinical Medicine
K. John Morrow Jr., Ph.D.
|
|
MDx Hones In On Near-Patient Setting
Nina Flanagan
|
|
Personalized Medicine Realizing Its Promise
Edward Abrahams, Ph.D.
|
|
Timing Rules for Biological Deposits in Flux
Joseph Hsiao
|
|
Activism, Mendacity, and Pathological Science
Henry I. Miller, M.D.
|
|
Cellular Imaging and Analysis Roundtable
|
|
Choosing the Right Model
|
|
Emory University Named to NCI Chemical Biology Consortium
|
|
Simplifying Antibody Conjugation Processes
Nick Gee, Ph.D.
|
|
Demystifying Medicinal Chemistry Efforts
Steve Gardner
|
|
Using Metabolomics to Optimize Bioprocessing
Don Rose, Ph.D.
|
|
Antidotes for an Ailing Biotechnology Sector
Sumantha R. Sedor
|
|
| August 1, 2009 (Vol. 29, No. 14) |
|
Addressing Ligand Binding Assay Deficiencies
Kevin Brady
|
|
Infectious Diseases a Key MDx Market Driver
Kevin Leong
|
|
Novel Alzheimer’s Therapies Gaining Ground
Carol Potera
|
|
GEN Update on Promising Emerging Biotechnologies
|
|
Microarrays for Gene-Expression Studies
Elizabeth Lipp
|
|
PCR Technology Review: Standardization of qPCR and RT-qPCR
Stephen A. Bustin, Ph.D. Jo Vandesompele, Ph.D. Michael W. Pfaffl, Ph.D.
|
|
Italian Biotech Revamps Old-World Mindset
Alberto Onetti, Ph.D. Charles S. Versaggi, Ph.D. Bruce F. Mackler, Ph.D., J.D.
|
|
Overcoming Phase II Attrition Problem
Allan B. Haberman, Ph.D.
|
|
Making Bioprocess Scale-Up More Robust
Angelo DePalma, Ph.D.
|
|
Bringing Greater Efficiency to Antibody Manufacturing
Susan Aldridge, Ph.D.
|
|
Bioreactor and Fermentor Market Trends
Vicki Glaser
|
|
Perspective on PR: Building an Effective Communication Program
Tony Russo, Ph.D.
|
|
Innovative Drug Screening Methodologies
K. John Morrow Jr., Ph.D.
|
|
Utilizing Biomarkers to Their Full Extent
Nina Flanagan
|
|
Ninth Circuit Rules on IP and Antitrust Issues
Christine Garrett Devlin William Diaz
|
|
Technological Advances Increase the Risk of Genetic Identity Theft
Alan McHughen, Ph.D.
|
|
Biosimilars and Follow-On Branded Biologics
Bruce F. Mackler, Ph.D., J.D.
|
|
Single-Use Noninvasive Sensing Technology
Jim Furey
|
|
High-Throughput Nanovolume qPCR
David Gelfand, Ph.D. Kumar Kastury, Ph.D.
|
|
Streamlining In Silico Compound Profiling
François Petitet
|
|
Stabilization Method for Biological Samples
Mats Borén, Ph.D.
|
|
Increasing Production Process Efficiency
Merlind Muecke, Ph.D. Susanne Leonhartsberger, Ph.D.
|
|
Biotechnology Investments Exhibit Resilience
Robert Dellenbach
|
|
| July 1, 2009 (Vol. 29, No. 13) |
|
Automating Magnetic Bead Multiplex Assays
Jason Greene
|
|
Stem Cell Possibilities Energize the Market
Harold Gross
|
|
Microsoft Strengthens Its Involvement in Life Sciences
Carol Potera
|
|
Building a Successful Biotech Incubator
Gail Dutton
|
|
Upgrading Cell-Based Viability Assays
K. John Morrow Jr., Ph.D.
|
|
Meeting Biomagnetic Separation Needs
Gail Dutton
|
|
Creating Therapies via the RNAi Route
Patricia F. Dimond, Ph.D.
|
|
High-End Mass Spec Systems Introduced
Vicki Glaser
|
|
Competition Mounting in Peptide Market
Vicki Glaser
|
|
European Overview: Firms Look for Niche in Peptide Synthesis
Sophia Fox
|
|
Getting Real with Downstream Processing
Angelo DePalma, Ph.D.
|
|
Applying Novel Biologic Production Methods
Susan Aldridge, Ph.D.
|
|
Getting the Most out of Quantitative PCR
Catherine Shaffer
|
|
Choosing a Clinical Trial Disclosure System
Satish Tadikonda
|
|
Navigating Pharmacogenomics Patenting
Y. Philip Zhang, Ph.D., J.D.
|
|
Therapy and Enhancement: Is There a Moral Difference?
Patrick Lin, Ph.D.
|
|
More from the Floor at ASMS: Boosting Analytical Capabilities
Vicki Glaser
|
|
Automating Physical Passage of Stem Cells
Kristi Hohenstein, Ph.D. Gary Bright, Ph.D. Anuradha Soundararajan
|
|
Expanding Disposable Depth-Filter Applications
Scott W. Anderson Mike Collins Manfred Muehl
|
|
Fluidics-Free Molecular Interactions Analysis
Krista Witte, Ph.D.
|
|
Significant Change Predicted for Bioindustry
Benjamin J. Conway
|
|
| June 15, 2009 (Vol. 29, No. 12) |
|
Solutions for DNA Copy-Number Analysis
Vanessa L. Ott, Ph.D.
|
|
The Rise of Short- and Rapid-Acting Opioids
Terence McManus, Ph.D.
|
|
Tackling Production Problems with Hydrogels
Carol Potera
|
|
Catching Up to Multiplexing Technology
Elizabeth Lipp
|
|
Protein Engineering Reaches New Frontiers
Nina Flanagan
|
|
Improving Biomarker Validation
Gail Dutton
|
|
Alternative Feedstocks Boost Ethanol Production
Vicki Glaser
|
|
Tech Transfer Key to CMO Cost Reductions
Susan Aldridge, Ph.D.
|
|
Nature and Nurture Benefit Cell Lines
Angelo DePalma, Ph.D.
|
|
Perspective: Boutique-Level Service in the CMO Sector
Roger Lias, Ph.D.
|
|
Banked-Specimen Retrospective Studies
Jeffrey Gibbs
|
|
Spotlight on the FDA
Bruce F. Mackler, Ph.D., J.D.
|
|
Screening Membrane-Associated Targets
Anthony L. Shrout , Ph.D.
|
|
Advancing Western Blots with Digital Imaging
Mike Collier, Ph.D. Lisa Isailovic Tamara R. Golden, Ph.D.
|
|
Real Time Multiplexed Protein Measurement
Wei Hu, Ph.D. Jean-Francois Houle, Ph.D. Paul Smith
|
|
2-D DIGE Improves Process Understanding
Åsa Hagner-McWhirter, Ph.D. Maria Winkvist, Ph.D. Lennart Björkesten, Ph.D. Gunnar Malmquist, Ph.D.
|
|
| June 1, 2009 (Vol. 29, No. 11) |
|
High-Content Cytotoxicity Analysis
Paul Wylie, Ph.D. Mike Janes
|
|
Molecular Cytogenetic Tools
Jonathan Witonsky
|
|
Ambit Has High Hopes for Kinase Screening Tool
Carol Potera
|
|
Long-Term Viability in a Down Market
Tamara Zemlo, Ph.D.
|
|
San Diego Pioneers Cleantech Solutions
Carol Potera
|
|
Novel Antibody Microarray Technology
Sophia Fox
|
|
Investigating and Focusing on Ion Channels as Drug Targets
Sue Pearson, Ph.D.
|
|
Epigenetics Fortifies Cancer Armamentarium
Gail Dutton
|
|
Delivery Approaches for RNAi-Based Drugs
James Netterwald, Ph.D.
|
|
Single-Cell Genomics Clarifies Big Picture
Richard A. Stein, M.D., Ph.D.
|
|
Overcoming Protein Production Hurdles
K. John Morrow Jr., Ph.D.
|
|
China Increases Healthcare Investment
Qing Xia Daming Chen
|
|
Ramping Up Flu Vaccine Efforts
Gail Dutton
|
|
Patentability of Genetic Sequences Limited
William L. Warren Lei Fang, Ph.D., M.D.
|
|
Science and Technology Are Essential to Economic Recovery
Henry I. Miller, M.D.
|
|
Purdue Scientist Gets Moving on Vaccine against H1N1
|
|
Controlling Nutrient Release in Cell Cultivation
Antje Neubauer, Ph.D. Russell Golson Kaisa Ukkonen Mirja Krause Hanna Tegel Jenny Ottosson Marianne Wittrup Larsen Karl Hult Peter Neubauer Antti Vasala
|
|
Using Mass Spectrometry for Tissue Imaging
Maria C. Prieto Conaway Shousong Cao Farukh Durrani Youcef Rustum Ping Wang Khin Marlar Latif Kazim
|
|
Managing Data from Screening Effectively
Andy Vines
|
|
Identifying New Gene-Expression Patterns
Nicola C. Day, Ph.D. Sandra Williams, Ph.D.
|
|
Improving Protein Yields in Mammalian Cells
Steven Williams, Ph.D. Rocky Cranenburgh, Ph.D.
|
|
Defending the Actions of Activist Shareholders
David Sable, M.D.
|
|
| May 15, 2009 (Vol. 29, No. 10) |
|
Managing Protein Biomarker Assay Workflow
Ruth A. VanBogelen, Ph.D. Richard C. Jones, Ph.D. M. Walid Qoronfleh, Ph.D.
|
|
Are In Vitro Diagnostics Recession-Proof?
Bruce Carlson
|
|
Forging Isobutanol with Modified Microbes
Carol Potera
|
|
Tough Times Ratchet Up Need for Partners
Susan Aldridge, Ph.D.
|
|
Natural Resources Buoy Chilean Biotech
Robert Yuan, Ph.D.
|
|
New MS Tools Advance Biomolecular Studies
K. John Morrow Jr., Ph.D.
|
|
CGH Sheds Its Light on Disease Etiology
Mary Addonizio
|
|
“Greening” of Labs and Manufacturing
Angelo DePalma, Ph.D.
|
|
Delivery Firms Focus on Efficiency & Efficacy
Patricia F. Dimond, Ph.D.
|
|
Nasal Administration Methods Stake Out Niche
Alan Smith, Ph.D.
|
|
Decoding Cell Communication
Kathy Liszewski
|
|
Strategies for Removing Viruses from Cell Lines
Gail Dutton
|
|
GEN's Spotlight on the FDA
Bruce F. Mackler, Ph.D., J.D.
|
|
Obtaining Reliable PCR from Seed DNA
Les Hoffman, Ph.D. Shannon Krueger
|
|
High-Speed Sample Volume Measurement
Chris Walsh
|
|
New Tool Recombineers the DNA of E. coli
Tim Zeppenfeld, Ph.D.
|
|
| May 1, 2009 (Vol. 29, No. 9) |
|
Lab Automation Protocols and Virtual Workcells
Alan H. Katz, Ph.D.
|
|
Securing a Slice of NIH Stimulus Funding
Christianne Bird
|
|
PharmAthene Secures Biodefense Position
Carol Potera
|
|
Emerging Biotechnology Clusters
Gail Dutton
|
|
ADMET Increasingly Integral to Discovery
Elizabeth Lipp
|
|
Practical Applications of Systems Biology
Richard A. Stein, M.D., Ph.D.
|
|
Ramping Up Effort for Improving Kinase Assays
Nina Flanagan
|
|
Novel Ways of Looking at Old Problems
K. John Morrow Jr., Ph.D.
|
|
Oligo Market Benefits from RNAi Focus
Vicki Glaser
|
|
HPLC Thrives on Speed and Efficiency
Angelo DePalma, Ph.D.
|
|
Recent Decisions Curtail Personalized Medicine
Brenda Herschbach Jarrell, Ph.D., J.D. Fangli Chen, Ph.D., J.D.
|
|
Rebuttal: Gov’t Should Not Open Coffers to VC Firms
William Bains
|
|
Arguments against President Obama’s Stem Cell Policies
Gilbert Meilaender, Ph.D.
|
|
Automated Capillary Isoelectric Focusing
|
|
Sugars Are Sweet
|
|
Small and Smaller
|
|
Identifying Cardiotoxic Compounds
Blake D. Anson, Ph.D. Junyi Ma, M.D., Ph.D. Jia-Qiang He, Ph.D.
|
|
Standardization in Biomarker Discovery
James R. Dasch, Ph.D. Keith R. Solomon, Ph.D. Marina Hincapie, Ph.D. David Sarracino, Ph.D.
|
|
Improving LC/MS Analysis of Oligonucleotides
Michael McGinley Gregory Scott
|
|
LIMS Streamlines Translational Science
Trish Meek
|
|
VC Lock-Down Mode Paralyzes Bioindustry
Rod Raynovich
|
|
| April 15, 2009 (Vol. 29, No. 8) |
|
Breaking HTS Cell-Based Assay Bottlenecks
James P. Brady Jr., Ph.D. Karen A. Donato, Ph.D.
|
|
Synthetic Bio's Promise Places It on Fast Track
Mark Bunger
|
|
Firm Aims to Regulate RNA in Rare Diseases
Ilene Schneider
|
|
Fine-Tuning Sample Preparation Techniques
Elizabeth Lipp
|
|
Budgets Shifting in Biopharma Manufacturing
Eric S. Langer
|
|
POC Testing Predicted to Transform Healthcare
Ian George, Ph.D.
|
|
Capitalizing on Fragment-Based Discovery
Kathy Liszewski
|
|
Focused Assays Lead to More Potent Drugs
Nina Flanagan
|
|
Novel Systems Zero In on the $100 Genome
K. John Morrow Jr., Ph.D.
|
|
Removing Impediments in Downstream Processing
Angelo DePalma, Ph.D.
|
|
Partnerships Strengthen Finland Biotech
Susan Aldridge, Ph.D.
|
|
Spotlight on the FDA
Bruce F. Mackler, Ph.D., J.D.
|
|
Transforming Bioprocessing as We Know It
|
|
Detection Method for Conformational Change
Joshua Salafsky, Ph.D.
|
|
Easing Challenges in QbD Implementation
Andreas Schneider
|
|
Accelerating Preclinical Imaging Workflow
Santosh S. Arcot, Ph.D.
|
|
| April 1, 2009 (Vol. 29, No. 7) |
|
High-Content Methods to Assess Toxicity
Mark A. Collins, Ph.D.
|
|
Cancer Molecular Diagnostics Take the Stage
Sudeep Basu, Ph.D
|
|
Firm on Quest to Improve Biomanufacturing
Carol Potera
|
|
Unveiling Cellular Bioenergetics’ Secrets
Richard A. Stein, M.D., Ph.D.
|
|
Digital Gene-Expression Profiling
Vicki Glaser
|
|
Traditional Strengths Solidify Chilean Biotech Industry
Gail Dutton
|
|
Ongoing Pursuit of Sustainable Operations
Angelo DePalma, Ph.D.
|
|
MDx Will Drive Personalized Medicine
Vicki Glaser
|
|
Unearthing More Effective Therapies for Anthrax
Matthew Meldorf, M.D.
|
|
Getting a Handle on Metabolic Disorders
David Daniels, Ph.D.
|
|
New qPCR Workflows Accelerate Discovery
Lloyd Dunlap
|
|
Gov’t Actions Buoy European Start-Ups
Susan Aldridge, Ph.D.
|
|
Enforceable Diagnostic Method Patents
Edmund R. Pitcher Brian A. Fairchild, Ph.D.
|
|
Deficiencies in Forensic Science Training Must Be Met Head-On
Richard E. Bisbing
|
|
Initiatives Advancing Chilean Life Sciences
Robert Yuan, Ph.D.
|
|
New and Old Technologies Boost Advances
Sophia Fox
|
|
Schizophrenia Research with Real Time PCR
|
|
Strategies for Measuring Viable Biomass
John Carvell
|
|
Measurement of Global DNA Methylation
Deborah L. Vassar Ernest J. Mueller, Ph.D. Savita Bagga, Ph.D.
|
|
Staying Ahead of Activist Stockholders
Joseph E. Gilligan Brian C. O'Fahey
|
|
| March 15, 2009 (Vol. 29, No. 6) |
|
Working with Cryopreserved Hepatocytes
Ji Young Lee, Ph.D. Timothy A. Moeller
|
|
Combating Hospital-Acquired Infections
Bruce Carlson
|
|
Honing In On Fatty Liver Disease Treatment
Joe Levit
|
|
Madoff Matters, But Larger Issues Loom
Gail Dutton
|
|
Making Improvements to Standard of Care for HCV
Elizabeth Lipp
|
|
Advances in Label-Free Assay Screening
Patricia F. Dimond, Ph.D.
|
|
Protein Microarrays See Broader Utilization
K. John Morrow Jr., Ph.D.
|
|
Fledgling Firms Needed to Fill U.K. Void
Susan Aldridge, Ph.D.
|
|
U.S. Biofuels Market Off and Running
Ellyn Kerr
|
|
miRNA Profiling Opens Doors for New Drugs
Nina Flanagan
|
|
Maximizing Value in Outsourcing Services
Kathy Liszewski
|
|
Economic Crisis Provides a Potential Boost to IP Portfolio
Narinder S. Banait, Ph.D., J.D.
|
|
Determining Small Molecule Binding Kinetic Constants
|
|
GEN BIO Theater Presentations
|
|
microRNA Expression Profiling of Carcinomas of Unknown Origin
|
|
Novel OncoMouse Model
|
|
China Gains in Innovative R&D
|
|
Mycoplasma Contamination in Culture Media
Maik W. Jornitz Theodore H. Meltzer , Ph.D.
|
|
Dissecting Protein-Protein Interactions
Eric J. Sundberg
|
|
Desorption Electrospray Ionization
Justin M. Wiseman Peter T. Kissinger
|
|
| March 1, 2009 (Vol. 29, No. 5) |
|
Drug Absorption on Membrane Arrays
Voula Kodoyianni, Ph.D. Christine Angevine, Ph.D.
|
|
Pharma’s Ongoing Quest for R&D Innovation
Carolyn Buck-Luce Mark B. Hassenplug
|
|
Agilent Expands Its Capabilities in Robotics
Carol Potera
|
|
Researchers Map Neanderthal Genome
|
|
Revitalizing Surface Plasmon Resonance
Diana Gitig
|
|
TechNote: High-Throughput Kinase Selectivity Profiling
Mazen Karaman, Ph.D. Dan Jones Paul Gallant
|
|
Review: LabAuto Product Introductions
Ilene Schneider
|
|
Shining a Different Light on Genetic Diversity
Richard A. Stein, M.D., Ph.D.
|
|
Quality Makes a Difference in RNA Prep
K. John Morrow Jr., Ph.D.
|
|
DNA Vaccines Inch Toward Human Use
Gail Dutton
|
|
Grappling With Biologic Manufacturing Concerns
K. John Morrow Jr., Ph.D.
|
|
CMOs Hold Their Ground in Troubled Times
Angelo DePalma, Ph.D.
|
|
Quest for Fully Disposable Process Stream
Vicki Glaser
|
|
Business Continuity & Recovery Strategies
Merrilee Galloway Mark Dyment
|
|
Personalized Medicine Grows in Fits and Starts
Lloyd Dunlap
|
|
Clinical Proteomics Heads Into Real World
N. Leigh Anderson, Ph.D.
|
|
Making the Most of Pre-IDE Meetings
Jeffrey Gibbs
|
|
China Stays Committed to Biodevelopment
Zhu Shen, Ph.D.
|
|
Standard Setting Increasingly Under Siege
Steven B. Pokotilow Amy E. Wilson, Ph.D. Benjamin P. Liu
|
|
Stem Cell Funding Roadblock
Bernard Siegel, J.D.
|
|
Measuring Multiplexed Signal Transduction
Shannon Henery Thaddeus George
|
|
Low Metabolic Burden Plasmid Production
Aaron E. Carnes James A. Williams
|
|
Impact of Risk Mitigation on Deal Market
Mark A. Metcalf
|
|
| February 15, 2009 (Vol. 29, No. 4) |
|
Second Messengers’ Accumulation Assays
Jean-Luc Tardieu, Ph.D.
|
|
Sky Could Be the Limit for DNA Testing
Bruce Carlson
|
|
Stratatech Builds on Cell Line Discovery
Carol Potera
|
|
PerkinElmer Retools Its Strategic Mission
Carol Potera
|
|
Case Study: Overcoming Antimicrobial Resistance
Ramin Najafi, Ph.D.
|
|
Does Offshoring Put Patents in Jeopardy?
Jeremy Minshull, Ph.D.
|
|
Low-Volume Liquid Handling Gaining Favor
Gail Dutton
|
|
Boosting Potential LC/MS Operations
Nina Flanagan
|
|
New Antibody Engineering Technologies
K. John Morrow Jr., Ph.D.
|
|
S. Korean Gov’t Nudges Biotech Along
Robert Yuan, Ph.D.
|
|
Pathway Knowledge Can Benefit Cancer Therapeutics
David Daniels, Ph.D.
|
|
Honing In on Targeted Resequencing
Kathy Liszewski
|
|
Overreacting to Perceived Risks
Henry I. Miller, M.D.
|
|
Recent Advances in NextGen Sequencing
|
|
Executive Interview: Reinhard Vogt, Sartorius Stedim Biotech
|
|
Modeling Ensemble Powers Systems Biology
Colin Hill
|
|
Peristaltic Aseptic Filling Instrumentation
Peter Lambert Chuck Treutel
|
|
Tools That Facilitate Metabolite Identification
Yingying Huang, Ph.D.
|
|
| February 1, 2009 (Vol. 29, No. 3) |
|
Simplification of Kinase Binding Assays
Steven M. Riddle
|
|
miRNA Solidifies Role in Disease Research
Christianne Bird
|
|
CytImmune Banks on Gold Nanoparticles
Ilene Schneider
|
|
GEN’s Annual Wall Street Roundup
|
|
European Bioindustry Upbeat in the Long Term
Susan Aldridge, Ph.D.
|
|
Epigenomics Rises as Key Research Tool
Richard A. Stein, M.D., Ph.D.
|
|
Improving Delivery of RNAi Drugs
Nina Flanagan
|
|
Israeli Initiatives Seek to Sidestep Funding Crisis
Vicki Glaser
|
|
Uncovering Applications for DNA Forensics
Elizabeth Lipp
|
|
Alternatives to Mammalian Expression
K. John Morrow Jr., Ph.D.
|
|
Targeting Post-Translational Modifications
Angelo DePalma, Ph.D.
|
|
Raising Molecular Imaging to Higher Level
Gail Dutton
|
|
Strategies to Overcome Blood-Brain Barrier
Allan B. Haberman, Ph.D.
|
|
Chinese Outsourcing Nears Full Service
Jim J. Zhang, Ph.D.
|
|
Court Ruling May Impact Life Science Patents
Jeffrey D. Hsi Elizabeth N. Spar
|
|
Venture Capital Firms Need Access to Government Coffers
J. Leslie Glick, Ph.D.
|
|
GEN’s MicroArray Challenge Solved
John Sterling
|
|
Promega's Protein Purification Project
|
|
Novozymes Exploits a Venerable Bioproduction Tool for Contract Manufacturing Operations
|
|
Visualizing Signal Transduction Pathways
Simon Fredriksson
|
|
GEN's Interview with Dr. Francisco J. Ayala
|
|
Accelerating Protease Drug Development
NIcholas J. Ede, Ph.D.
|
|
Three-Dimensional Cultivation of Cells
Hans Hoffmeister, Ph.D.
|
|
| January 15, 2009 (Vol. 29, No. 2) |
|
Tools for Studying Membrane Protein Targets
Soma S.R. Banik, Ph.D. Christopher J. Laing, Ph.D. Benjamin J. Doranz, Ph.D.
|
|
Capitalizing on Novel Expression Systems
Eric S. Langer
|
|
GenomeQuest Aims to Streamline Genomics
Carol Potera
|
|
Japanese BioAlliance Strategies Evolving
Tom Burger James E. Foley, Ph.D.
|
|
Automation Drives Laboratory Economics
Catherine Shaffer
|
|
Identifying Best Practices for Advanced Therapies
Susan Aldridge, Ph.D.
|
|
Exploiting the Value of Cancer Biomarkers
Diana Gitig
|
|
Enhancing PCR for Diagnostic Applications
Lloyd Dunlap
|
|
Microfluidics Makes Strides to Fulfill Promise
Kathy Liszewski
|
|
Does Fusion Therapy Have a Role in Cancer?
John M. Pawelek, Ph.D.
|
|
Culture Media Underly Productivity Gains
Angelo DePalma, Ph.D.
|
|
Keeping the “Person” in Mind in Personalized Medicine
Peter Traber, M.D.
|
|
BD Biosciences Expands Capabilities in Cell Culture Media
|
|
Shut-off Switch for Cellulose Production Found
|
|
Finessing PI3 Kinase Assay Development
Kevin Entwistle
|
|
Minimizing Challenges in Biological Modeling
Kristen Zanella
|
|
Researchers Tackle Tumors One Cell at a Time
Frank Feist
|
|
Optimization of Binding Interaction Studies
Laura Moriarty, Ph.D.
|
|
Online Monitoring of In-Process Samples
Tanya Jenkins
|
|
| January 1, 2009 (Vol. 29, No. 1) |
|
High-Throughput Automation of DNA Extraction
David Saul, Ph.D. Nick Price, Ph.D.
|
|
Fast Growth Foreseen for Protein Therapeutics
Andrea Hiller
|
|
Sequella Takes On Pernicious Enemies
Ilene Schneider
|
|
High-Content Screening Rapidly Evolving
David Daniels, Ph.D.
|
|
Linking Disease to Gene Variations
Vicki Glaser
|
|
Cautious Optimism Prevails for Chinese Biotechnology
Gail Dutton
|
|
Exploring the Human Proteome in Depth
Elizabeth Lipp
|
|
Utilization of DNA Microarrays Increasing
K. John Morrow Jr., Ph.D.
|
|
Peptide Capacity Holding Steady For Now
Vicki Glaser
|
|
Stem Cells Continue March Toward Clinic
Nina Flanagan
|
|
Korea Lays Groundwork for Future Success
Robert Yuan, Ph.D.
|
|
Update on Patent Law Revisions in China
Lisa A. Haile, J.D., Ph.D.
|
|
Will New Appointment Wax Healthcare Reform?
Rod Raynovich
|
|
Beijing Institute of Genomics Expands Applications for Life Technologies’ SOLiD System
|
|
Technology Showcase for New Screening Software
|
|
Celebrating Charles Darwin in 2009
John Sterling
|
|
Impact of Ultrafiltration of Hydrolysates
Tobi Limke, Ph.D.
|
|
Tritiated Opiate Receptor Radioligands
Crist N. Filer, Ph.D.
|
|
Assessing a Company’s Financial Health
David Sable, M.D.
|
|
| December 1, 2008 (Vol. 28, No. 21) |
|
Utilization of an Automated Triplex Assay
Andrew Niles Simon T.M. Allard, Ph.D. Jason Greene Sarah Shultz
|
|
Moving Flow Cytometry Beyond Core Facilities
Madhu Sharma, Ph.D.
|
|
Tripos International Returns to Its Roots
Carol Potera
|
|
Q&A: Life Technologies Formed from AB/Invitrogen
David Daniels, Ph.D.
|
|
Doubts Stymie Implementation of RFID
Angelo DePalma, Ph.D.
|
|
Zeroing in on PI3K Pathway
Nina Flanagan
|
|
Spain Invests in Quest for Big Biotech Payoff
Sue Pearson, Ph.D.
|
|
Flow Cytometry Applications Proliferate
Sophia Fox
|
|
Update on Emerging Biobanking Practices
Catherine Shaffer
|
|
Improving Delivery thru Nanotechnology
Gail Dutton
|
|
Status of Biosimilars in U.S. Could Soon Change
Veronica Mullally
|
|
Tips on How to Properly Construe Patent Claims
John P. Iwanicki
|
|
Vilification of Bovine Growth Hormone Udderly Unwarranted
Henry I. Miller, M.D.
|
|
New FC Systems Measure More Variables Over Shorter Time Periods
K. John Morrow Jr., Ph.D.
|
|
Methylation-Sensitive Hi-Res Melting Analysis
Cameron N. Gundry Mikeal Wall Jason T. McKinney Colleen Hough, Ph.D. Lindsey Cutler John D. Phillips, Ph.D. Margaret K. Yu, M.D. David H-F Teng, Ph.D.
|
|
Optimizing Mammalian Cell Culture Performance
Sally Grosvenor
|
|
Taking Old & New Molecules Down Novel Paths
Stephen R. Byrn, Ph.D.
|
|
Sourcing Well-Characterized Biospecimens
Samir Alhasan, Ph.D. Shannon Richey Apurvi Desai
|
|
Biotech’s Umbilical Cord Has Been Severed
Peter Winter
|
|
| November 15, 2008 (Vol. 28, No. 20) |
|
Use of a Nano-Structured Proteomic Biochip
Anna A. Fisher, Ph.D. James C. Nelson, Ph.D. David Ure
|
|
GPCR Market Exhibits Rapid Diversification
Ken Rubenstein, Ph.D.
|
|
Aiming to Accelerate Discovery Process
Carol Potera
|
|
Methodology Garners Researchers’ Interest
Carol Potera
|
|
New Zealand Biotech Poised for Growth
Janet Mason
|
|
Achieving Success in Tox Studies
Gail Dutton
|
|
Synthetic Biology Finds a Niche in Fuel Alternatives
Elizabeth Lipp
|
|
Understanding the Biology of RNAi
Lloyd Dunlap
|
|
Single-Use Filtration Hits the Mainstream
Angelo DePalma, Ph.D.
|
|
Adroit Crafting of “Intended Use” Critical
Jeffrey Gibbs
|
|
Outsourcing Medicinal Chemistry Activities
Vicki Glaser
|
|
Industry Briefing: Adapting to a Transformed Economic World
Susan Aldridge, Ph.D.
|
|
Amylin Builds on the Success of Byetta
Querida Anderson
|
|
New Treatment Strategies for Inflammation Gain Ground
Yuval Cohen
|
|
Structure of Critical GPCR Determined
|
|
Companies Collaborate to Provide Integrated Solution to Preclinical Laboratory Workflow
|
|
LIMS Addresses Major Biobanking Challenges
Doug Holbrook
|
|
Off-Gas Analysis for Real-Time Process Control
Karin Koller
|
|
Chromatographic Column Characterization
Michael McBrien
|
|
| November 1, 2008 (Vol. 28, No. 19) |
|
Automating Cell Culture Operations in R&D
Lara Marchetti, Ph.D.
|
|
Photonics Poised to Cross Over into Biotech
Andrea Hiller
|
|
Firm Invests in New HIV Vaccine Strategy
Carol Potera
|
|
Removing Antigen Discovery Guesswork
Carol Potera
|
|
Waging a Multipronged Alzheimer’s War
Vicki Glaser
|
|
MS Sample Prep–Challenges and Pitfalls
K. John Morrow Jr., Ph.D.
|
|
Critical Issues When Selecting a CMO
Eric S. Langer
|
|
Accelerating Research into Clinical Setting
Winston Patrick Kuo, D.D.S., D.M.Sc. Robert J. Distel, Ph.D.
|
|
Identifying Biochemical Threats Earlier
Gail Dutton
|
|
Latin American Biotech Steadily Emerges
Bruce F. Mackler, Ph.D., J.D.
|
|
qPCR Methods Expand Rapidly
David Daniels, Ph.D.
|
|
Vaccine Development Aided by New Techniques
Angelo DePalma, Ph.D.
|
|
Is Safe Harbor Closed to Research Tools?
William L. Warren Donna Best
|
|
Quo Vadis Biofuels Projects?
Michael S. Koeris, Ph.D. Student
|
|
Biofuel Standards
|
|
DNA Vaccines Meeting
|
|
New Multiplex Approach for Rapid Diagnostics
|
|
Production of High Secretion Cell Lines
Imran Clark, Ph.D. HaYong Lim Kristi Hohenstein, Ph.D. Gary Bright, Ph.D.
|
|
mRNA Analysis with Next-Gen Sequencing
Gary P. Schroth, Ph.D.
|
|
Unfulfilled Promise of Predictive Toxicology
Joseph Zock Rebecca J. Palmer
|
|
Using Microdosing to Enhance Development
Graham Johnson, Ph.D.
|
|
Preparing for a Shrinking Economic World
Daniel Ruppar
|
|
| October 15, 2008 (Vol. 28, No. 18) |
|
High-Throughput Live-Cell Imaging Assays
Carolyn Conant, Ph.D.
|
|
Animal Therapeutics and Diagnostics
Melissa Elder
|
|
Taking DNA-Guided Medicine to the Clinic
|
|
Engineering Droplets for DNA Sequencing
Carol Potera
|
|
Cashing in Your Chips to Advance Discovery
K. John Morrow Jr., Ph.D.
|
|
Benefits of Integrating IT and Team Building
David Dunn
|
|
Strengthening Mammalian Cell Culture
Angelo DePalma, Ph.D.
|
|
Exploiting Advances in Image Analysis
Richard A. Stein, M.D., Ph.D.
|
|
Regenerative Therapies Gain Momentum
Elizabeth Lipp
|
|
Deciphering Biological Networks
Kathy Liszewski
|
|
Fine-Tuning the Design of GPCR Therapeutics
Carol Potera
|
|
Patent Update: Redefining Written Descriptions for Patents
William L. Warren Mark Westhafer, Ph.D.
|
|
VC Funding for Biotech Firms
J. Leslie Glick, Ph.D.
|
|
What's Driving Dealmaking in Biopharma?
|
|
Advanced Imaging Applications
Richard A. Stein, M.D., Ph.D.
|
|
Screening Test for Traumatic Brain Injury
Galina Bernstein, Ph.D. Wei Hu, Ph.D.
|
|
Validation of Protein Quantification Assays
Katja Aschermann, Ph.D. Martin Blüggel Andreas Wattenberg, Ph.D.
|
|
Taking Aim at Gene-Regulation Research
Constanze Kindler, Ph.D.
|
|
Expediting Purification of Cellular Proteins
Manfred Koegl, Ph.D.
|
|
| October 1, 2008 (Vol. 28, No. 17) |
|
Quantifying Cell Migration and Invasion
Keren I. Hulkower, Ph.D. Maria Perr
|
|
Lipid-Modifying Therapies Face Flat Sales
Sreten Bogdanovic, Ph.D.
|
|
ZyGEM Builds DNA Extraction Kit Portfolio
Carol Potera
|
|
Bacteriophage-Based Antibiotic Therapy
Carol Potera
|
|
Opinion: Reining In New Therapeutic Hype Is Critical
Michael Feehan, Ph.D. Rich Durante, Ph.D.
|
|
Protein Quantification Pinpoints Targets
K. John Morrow Jr., Ph.D.
|
|
Predicting Adverse Drug Reactions
Susan Aldridge, Ph.D.
|
|
FDA Pushes PAT and Companies Shove Back
Eric S. Langer
|
|
Cell Imaging Makes Strides in Drug R&D
Nina Flanagan
|
|
Biomarker Assay Use Increases
Lloyd Dunlap
|
|
CMOs See Robust Growth
William Downey
|
|
Redefining Obviousness After KSR Decision
George C. Yu John Kappos
|
|
Substantive Progress Is Being Made in Breast Cancer Survival
Judith-Anne Chapman, Ph.D.
|
|
Novel Cell Culture Optimization Strategy
Cindy Neely, Ph.D.
|
|
Enzyme Immobilization on Polymeric Resins
Jon Fisher
|
|
Tools for Enhancing Vitamin D Therapeutics
Christian Helvig, Ph.D. Martin Petkovich, Ph.D.
|
|
Targeted Genome Editing via ZFN Methodology
Greg Davis, Ph.D. Trevor Collingwood, Ph.D. Phil Simmons
|
|
Molecular Diagnostics Take Center Stage
Rod Raynovich
|
|
| September 15, 2008 (Vol. 28, No. 16) |
|
Assay Tools for Nuclear Hormone Receptor Studies
Mahesh Mathrubutham, Ph.D. Patricia Whaley, Ph.D. Tom Wehrman, Ph.D. Keith Olson, Ph.D.
|
|
Pitfalls Undermine Promise of Theranostics
Kenneth P. Krul, Ph.D.
|
|
Chemical Firm Enters Biopharma CMO Sector
Susan Aldridge, Ph.D.
|
|
Firm’s Pipeline Targeted at HPV and Cancer
Carol Potera
|
|
Biotech Crops Directly Tied to Higher Yields
Terry Wanzek
|
|
Capitalizing on the RNAi Space Expansion
Elizabeth Lipp
|
|
Metabolite Profiling Speeds Diagnostic Efforts
K. John Morrow Jr., Ph.D.
|
|
Disposable Use Proliferates in Production
Angelo DePalma, Ph.D.
|
|
Users Are Sold on Single-Use Systems
Eric S. Langer
|
|
Refining Protein Drug Formulation
David Daniels, Ph.D.
|
|
FDA Backs PAT to Help Solve Manufacturing Woes
Lloyd Dunlap
|
|
RNAi’s Potential Is Spurring Alnylam’s Value
Querida Anderson
|
|
Thwarting Domestic Terrorism
Henry I. Miller, M.D.
|
|
Using Metabolomics in Biomarker Discovery
Walter E. Gall, Ph.D.
|
|
mAb Capture from Unclarified Feedstock
Allan Lihme Rob Noel, Ph.D.
|
|
Standard Materials for Clinical Proteomics
Peter Schulz-Knappe
|
|
Improving High-Res Mass Spec Formula ID
Don Kuehl
|
|
| September 1, 2008 (Vol. 28, No. 15) |
|
Proficient Use of Sandwich Antibody Arrays
Roberto Campos-Gonzalez, Ph.D. Kathy Brumbaugh, Ph.D. Dave Finkel Greta Wegner, Ph.D. Jackie Ernst
|
|
Nucleic Acid Purification Market Expands
Christianne Bird
|
|
Platform Simulates Human Capillaries
Carol Potera
|
|
Delivery of Time-Lapsed Live-Cell Imaging
Carol Potera
|
|
Peptide Drugs Becoming More Prevalent
Vicki Glaser
|
|
In-Line Analytics Improve Manufacturing
Gail Dutton
|
|
Cell Counting and Process Monitoring
Susan Aldridge, Ph.D.
|
|
USPTO Backlog Impacts Biopharma Industry
Anthony Tridico Jim Kastenmayer Ali Kargbo
|
|
Makeover Mandated for U.K. Life Science Sector
Sophia Fox
|
|
Marketing Analysis: What Is the Future of DTC Drug Advertising?
Wendy Macias, Ph.D.
|
|
Roundtable Discussion: Future High-Throughput Screening Directions
|
|
Next-Generation Sequencing Update
Richard A. Stein, M.D., Ph.D.
|
|
Improving R&D as well as Disease Prognosis
Nina Flanagan
|
|
Creative Applications of qPCR Proliferate
Catherine Shaffer
|
|
FDA Seeks to Establish Branch Office in China
Gail Dutton
|
|
Bio Directive Fails to Unify European Law
Matthew Royle Gareth Morgan Simon Cohen
|
|
Undermining Scientific Credibility
Alan McHughen, Ph.D.
|
|
Sample Quantitation with Microvolume Tools
Joel Hansen, Ph.D. Philippe Desjardins
|
|
Finding Proteins in Cell-Conditioned Media
Judith Nagy, Ph.D. Yunyi Kang Anthony Cass Athanasios Mantalaris
|
|
Automated Purification for Genetic Trait Maps
Jethro Holter Tone Yrvum
|
|
Spiral Countercurrent Chromatography
Martha Knight, Ph.D.
|
|
Digital Pathology in Preclinical Research Arena
Steve Potts, Ph.D.
|
|
VC Funding for Biotech Companies Withering
Robert Dellenbach
|
|
| August 1, 2008 (Vol. 28, No. 14) |
|
Achieving Precision Analysis with ELSD
Simon Robinson
|
|
Pharma Outsourcing on Upward Trajectory
Bruce Carlson
|
|
SRI Boasts Abilities in Early- and Late-Stage R&D
Carol Potera
|
|
Company Touts Its Novel Sequencing Technique
|
|
Is the U.K. Biotech Industry on the Skids?
Sue Pearson, Ph.D.
|
|
Antibody Processing Platforms Evolve
K. John Morrow Jr., Ph.D.
|
|
Flexibility Crucial in Bioreactor Systems
Elizabeth Lipp
|
|
Regulatory Pathways for Molecular Dx
Jeffrey Gibbs, Esq.
|
|
A Sensible Approach to Interpreting Research
Elizabeth M. Whelan, M.D.
|
|
Strengthening the Biotechnician Workforce
John Sterling
|
|
GEN Review BIO 2008: Tips for Doing Business in China and India
Gail Dutton
|
|
GEN Review BIO 2008: Grappling with the Regulation of Biosimilars
K. John Morrow Jr., Ph.D.
|
|
GEN Review BIO 2008: News from the Floor of BIO's Annual Meeting
|
|
Roundtable Discussion: High-Throughput Screening Challenges
|
|
Novel Approaches to Lead Optimization
Elizabeth Lipp
|
|
Protein Analysis Technologies Overview
Vicki Glaser
|
|
Applicability of Biomarkers Is Far-Reaching
David Daniels, Ph.D.
|
|
Ancillary Analysis Tools for Microarrays
Sophia Fox
|
|
Novel MS Systems Expedite Workflow
Gail Dutton
|
|
Platform Technologies Ease Scale-Up Pain
Angelo DePalma, Ph.D.
|
|
Batch Failure Rates in Biomanufacturing
Eric S. Langer
|
|
Graduate Programs that Prepare for NonResearch Careers
Molly B. Schmid
|
|
Advancing Gene Expression Studies
Lloyd Dunlap
|
|
Monoliths Emerge as Key Purification Methodology
Pete Gagnon
|
|
Enforceability of Patent Licenses Under Fire
Courtenay C. Brinckerhoff
|
|
Successful Genetic Tests Are Predicated on Clinical Utility
Diane Allingham-Hawkins, Ph.D.
|
|
Small-Scale Parallelized Biochromatography
Lothar Britsch, Ph.D. Tim Schroeder Jurgen Friedle, Ph.D.
|
|
Making Antibiotics Obsolete in Fermentation
Daniel Stieber, Ph.D. Philippe Gabant, Ph.D. Cedric Szpirer, Ph.D.
|
|
Fast PCR with Long and Difficult Amplicons
Haiyang Grunenwald, Ph.D.
|
|
Measurement of Proteins in FFPE Tissue
Casey Eitner David B. Krizman, Ph.D.
|
|
| July 1, 2008 (Vol. 28, No. 13) |
|
Bioluminescent Assays for Potency Assessment
Sarah Schultz Andrew Niles Jey Cheng, Ph.D. Simon T.M. Allard, Ph.D.
|
|
Adoption of Molecular Diagnostics Slowing
Kevin Leong
|
|
Firm's Bailiwick Based on Protein-Protein Expertise
Carol Potera
|
|
Compound Discovery Tools Still Evolving
Elizabeth Lipp
|
|
Can In Silico Modeling Speed Development?
K. John Morrow Jr., Ph.D.
|
|
Biomagnetic Separations See Increased Use
Gail Dutton
|
|
Reducing Downstream Purification Costs
Angelo DePalma, Ph.D.
|
|
Peptide Boom Puts Pressure on Synthesis
Susan Aldridge, Ph.D.
|
|
Staying Ahead of Upstream Developments
Susan Aldridge, Ph.D.
|
|
Quantifying Downstream Capacity Crunch
Eric S. Langer
|
|
Primer on Regulation of Diagnostic Assays
Jeffrey Gibbs, Esq.
|
|
Conquering RNAi Delivery Challenges
Kathy Liszewski
|
|
Sample Prep Initiatives Will Advance Proteomics
Nina Flanagan
|
|
Preventing Discord in Research Collaborations
Stewart Lyman, Ph.D.
|
|
Trends in Synthesis and Manufacturing
Diana Gitig
|
|
Recasting the Federal Debate on Stem Cells
Joseph R. Sollee
|
|
GINA Provides Bioindustry Boost
Sharon Terry Joann Boughman, Ph.D.
|
|
Assay: Avoiding Interference in Immunoassays
Tobias Polifke, Ph.D. Peter Rauch, Ph.D.
|
|
Choosing a Normalization Strategy for RT-PCR
Anders Bergkvist Amin Forootan Neven Zoric Linda Strombom Robert Sjoback Mikael Kubista
|
|
Focusing on Task of Reinventing Peptide Drugs
Warren P. Levy, Ph.D.
|
|
Strategies for Streamlining Bioproduction
Jill Staggert
|
|
The Paradox of Biotechnology Value Investing
David Sable, M.D.
|
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| June 15, 2008 (Vol. 28, No. 12) |
|
Planning for Success in Biomarker Discovery
Enrique A. Dalmasso, Ph.D.
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SNPs—A Shortcut to Personalized Medicine
Bruce Carlson
|
|
Almac Offers a Range of Integrated Services
Susan Aldridge, Ph.D.
|
|
Overcoming Complications in Multiplexing
Catherine Shaffer
|
|
Managing Asthma and COPD Treatments
Sue Pearson, Ph.D.
|
|
TechUpdate: Are Lentiviral Vectors on Cusp of Breakout?
Tim Ravenscroft
|
|
Turning Research into Viable Cancer Drugs
John F. Wong, Ph.D.
|
|
Tackling Drug-Interaction Issues Early On
Elizabeth Lipp
|
|
Finding Balance in Cell-Line Development
Angelo DePalma, Ph.D.
|
|
Methods for Maximizing Antibody Yields
K. John Morrow Jr., Ph.D.
|
|
Optimizing Utilization of Biomarkers
Kathy Liszewski
|
|
Flexibility Is the Name of the Game for CROs
Lloyd Dunlap
|
|
Osiris Trumpets Its Adult Stem Cell Product
Querida Anderson
|
|
No Member of Congress Left Behind
Henry I. Miller, M.D.
|
|
Counting Chromosome Copy Numbers Efficiently
Roland Kirchner, Ph.D. Claudia Holzhauer Frank Feist Wolfgang Mann, Ph.D. Marianna Alunni-Fabbroni, Ph.D.
|
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Improving Synthetic Oligo Purification Process
Gregory Scott Cathy Cordova Michael McGinley
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|
| June 1, 2008 (Vol. 28, No. 11) |
|
Cell Signaling Analysis Using Multiplex Assays
Scott Hayes, Ph.D. Robyn M. Perrin, Ph.D.
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Adults Now Drive Growth of Vaccine Market
Bruce Carlson
|
|
Novel Treatment Approach Leverages Epigenetics
Carol Potera
|
|
RNAi Researchers Galvanized by Advances
Elizabeth Lipp
|
|
Interrupting Protein-Protein Interactions
Diana Gitig
|
|
PAT Initiative Helps Move HPLC Forward
Angelo DePalma, Ph.D.
|
|
Norway's Oncology Efforts Are Coalescing
Susan Aldridge, Ph.D.
|
|
BioInsights: Biotech Industry Success Powered by Innovation
James C. Greenwood
|
|
Superbugs vs. Superdrugs: Race Goes On
Sue Pearson, Ph.D.
|
|
Ion Channels Play Key Role in R&D
David Daniels, Ph.D.
|
|
Digging for Insights through High-Content Data Mining
Gail Dutton
|
|
Off-Label Promotion Under Scrutiny by DOJ
Peter S. Spivack
|
|
Recreational Ancestry–Caveat Emptor?
Jonathan Marks, Ph.D.
|
|
Dispersive Raman Spectroscopy Utilization
Nesredin A. Mussa, Ph.D. Benjamin P. Locwin
|
|
Honing In on Chemoresistance Pathways
Michael D. Becker
|
|
Observing Stem Cell Growth and Viability
Jennifer L. Peters, Ph.D. William E. Jastromb
|
|
Inducement of Gene Expression or Silencing
Sanjay Vasu, Ph.D. Jian-Ping Yang, Ph.D. Adam N. Harris, Ph.D. Wieslaw Kudlicki, Ph.D.
|
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Tips for Emerging Firms on Obtaining Funding
Barbara Schilberg
|
|
| May 15, 2008 (Vol. 28, No. 10) |
|
Strategy to Improve Quantitative Telomere FISH
Rajiv Raja, Ph.D. Zuguo Li, Ph.D. Yun-Ling Zheng, Ph.D.
|
|
Demand for Novel Delivery Systems Rising
Bill Martineau
|
|
Company Seeks to Shake Up Protein Analysis
Sophia Fox
|
|
Symbiotic Firms Zero In on Enzymatic Tools
Carol Potera
|
|
Optimizing the Profiling of Protein Kinases
Patricia F. Dimond, Ph.D.
|
|
ELNs Ready for Large-Scale Deployment
Gail Dutton
|
|
Quest for Cancer Therapeutics Redirected
Irena Melnikova, Ph.D.
|
|
Applying aCGH to Molecular Diagnostics
Kathy Liszewski
|
|
Mass Spec Solidifies Discovery Role
Nina Flanagan
|
|
Filling Oligo Production Void
Vicki Glaser
|
|
Mannkind Persists with Inhaled Insulin
Querida Anderson
|
|
Genetic Science Confounds Students
Kenna Shaw, Ph.D. Katie Van Horne Joann A. Boughman, Ph.D.
|
|
Politically Speaking: Candidates Opine on Biotech & Health Issues
|
|
Obstacles to Presterilized Single-Use Filling
Jeff Jackson
|
|
Applications of New Synthesis Technologies in Drug Discovery and Development
William J. Blake, Ph.D. Andy Rakestraw, Ph.D. Patti M. Aha
|
|
| May 1, 2008 (Vol. 28, No. 9) |
|
Site-Specific Phosphorylation Profiling
Tim Nadler, Ph.D. Ed Machuga
|
|
“Active” Products Drive Wound-Care Market
Toby Zaleski, Ph.D.
|
|
Targeting Diabetes-Related Heart Disease
Carol Potera
|
|
Search Continues for Injection Alternatives
Susan Aldridge, Ph.D.
|
|
Capitalizing on Abundant Opportunities in Wales
Susan Aldridge, Ph.D.
|
|
Introducing In Vitro ADMET Studies Earlier
David Daniels, Ph.D.
|
|
GPCRs Remain “Hot” Drug Targets
Elizabeth Lipp
|
|
Bioprocess Advances Aim to Streamline Operations
Vicki Glaser
|
|
Versatility Concerns Impact Facility Design
Angelo DePalma, Ph.D.
|
|
Quantification & Identification in Proteomics
Vicki Glaser
|
|
Tools for Protein Structure Characterization
K. John Morrow Jr., Ph.D.
|
|
Court Blocks PTO-Initiated Patent Reform
Courtenay C. Brinckerhoff
|
|
Cancer Stem Cells: Fact or Fiction
George L. Gabor Miklos, Ph.D. Phillip J. Baird, M.D., Ph.D. Ian E. Haines, M.D.
|
|
Boosting Microplate Reader Functionality
Franka Ganske, Ph.D. Michael Fejtl, Ph.D. Marjan Orban, Ph.D.
|
|
Use of Continuous Plate Reactor Technology
Barry Johnson, Ph.D. Johan Persson Tom Thane Nielsen
|
|
Biosimilars Are Poised to Influence the Industry
Viren Mehta, Pharm.D. Eric Snyder, Ph.D.
|
|
| April 15, 2008 (Vol. 28, No. 8) |
|
Combining Microscopy with In Vivo Imaging
Timothy Alan Sutton, M.D., Ph.D. Kenneth William Dunn, Ph.D.
|
|
Cell-Based Assay Utilization Is On the Upswing
Shankar Sellappan, Ph.D.
|
|
Anthill Addresses Chemical Synthesis Needs
Carol Potera
|
|
Emerging Firms Highlighted at Roth Meeting
Ilene Schneider
|
|
Cell-Based Assay R&D Role Expands
Kathy Liszewski
|
|
Downstream Bottlenecks: Are They Myth or Reality?
Gail Dutton
|
|
HTS Carving Out Hit-to-Lead Position
Nina Flanagan
|
|
Roche All Set to Launch xCELLigence System
John Sterling
|
|
Increasing Yield in Nucleic Acid Sample Prep
Vicki Glaser
|
|
Managing Data from Next-Gen Sequencing
William Van Etten, Ph.D.
|
|
Creating a Life Science Cluster in Florida
Tamlyn Oliver
|
|
Celera Readies Itself for Possible Spin-Off
Querida Anderson
|
|
Using DNA Traceability to Track Meat and Ensure Safety
Patrick Cunningham, Ph.D.
|
|
Quantifying Pipette Variability due to Humidity
Doreen Rumery
|
|
Producing Proteins for New Drug Development
Soon Seog Jeong, Ph.D. Hui Feng, Ph.D. Gabriel Cubberley Maria Borovilos
|
|
Development of an Ion-Exchange Process
Anthony R. Newcombe, Ph.D. Claire Newcombe Richard Francis
|
|
| April 1, 2008 (Vol. 28, No. 7) |
|
Studying Protein Interactions in Living Cells
Ryan D. Bomgarden, Ph.D.
|
|
Aging ELISA Realm Takes Benchmark Role
Christianne Bird
|
|
Increasing the Odds of In Vitro Fertilization
Carol Potera
|
|
Saskatchewan Looks Past AgBiotech Roots
Carol Potera
|
|
Cancer Biomarkers Expedite Detection
K. John Morrow Jr., Ph.D.
|
|
Regulations Still Driving Stability Testing
Angelo DePalma, Ph.D.
|
|
Revolutionizing Protein Expression in R&D Arena
Elizabeth Lipp
|
|
Metabolomics Studies Rise in Quality
Susan Aldridge, Ph.D.
|
|
New Solutions Make qPCR a Rapidly Advancing Field
David Daniels, Ph.D.
|
|
U.S. Gene Patents in Legal Limbo –– for Now
Janis K. Fraser, Ph.D.
|
|
Defending Pharma Companies
J. Leslie Glick, Ph.D.
|
|
Removing Color Impurities in Biomanufacturing
Jon Fisher Amie Gehris John Maikner
|
|
Biobanks Can Make or Break Biomarkers
Kevin Krenitsky, M.D.
|
|
Combined Correctness Can Enrich Proteomics
Ola Forsstrom-Olsson Anna Kapferer
|
|
Alzheimer’s Market Set to Grow Substantially
Rod Raynovich
|
|
| March 15, 2008 (Vol. 28, No. 6) |
|
Machine Vision Improves HTS Quality Control
Jason Cassaday
|
|
Growth Foreseen for Ophthalmology Sector
Hermann A. M. Mucke, Ph.D.
|
|
Fermentas Learned Fast How to Go Global
Ilene Schneider
|
|
Cellectar’s 3-Step Process to Target Tumors
Carol Potera
|
|
Funding Issues Stymie Pandemic Preparation
Sue Pearson, Ph.D.
|
|
Getting More Out of Poor RNA Samples
Kathy Liszewski
|
|
Applications Broaden for Epitope Mapping
K. John Morrow Jr., Ph.D.
|
|
New Products Expand Use of Disposables
Angelo DePalma, Ph.D.
|
|
Fragment-Based Approach Increases Leads
Elizabeth Lipp
|
|
Surmounting Small Molecule Challenges
Nina Flanagan
|
|
Automating and Unifying Lab Workflow
Ilene Schneider
|
|
Protein Microarray Uses Abound
Vicki Glaser
|
|
CROs Step Up Activities in Developing Countries
Gail Dutton
|
|
Paucity of Biopharma Approvals Raises Alarm
Ronald A. Rader
|
|
Monogram Enters Theranostic Market
Querida Anderson
|
|
Designing Improved Humans
Henry I. Miller, M.D.
|
|
Fine-Tuning Compound Safety Assessments
Richard Brennan, Ph.D.
|
|
Identifying MRSA with Multiplex Sequencing
T. Vinayagamoorthy, Ph.D. Roger Hodkinson
|
|
Metabolic Monitoring Enhances Production
Bo Xu, Ph.D. Jens Gram, Ph.D.
|
|
| March 1, 2008 (Vol. 28, No. 5) |
|
Development of a Real-Time Immunoassay
Jean-Francois Houle, Ph.D. Paul Smith
|
|
qRT-PCR Ready for Rapid Growth Worldwide
Shankar Sellappan, Ph.D.
|
|
Solutions for Automating a Cell Culture Process
Susan Aldridge, Ph.D.
|
|
Staying Focused on Rodent-Breeding Business
Carol Potera
|
|
Life Science Compensation Trends Upward
Bryan Pearce
|
|
Oulu Region Lures Biotechnology Firms
Susan Aldridge, Ph.D.
|
|
Tapping miRNA-Regulated Pathways
Vicki Glaser
|
|
Small Biotechnology Firms Reach Out to CROs for Help
Nina Flanagan
|
|
Pharmaceutical Manufacturing Goes Green
Vicki Glaser
|
|
Innovations Mark Biosensor Development
K. John Morrow Jr., Ph.D.
|
|
Next-Generation Sequencing Picks Up Pace
Lloyd Dunlap
|
|
Optimizing Transient Gene Expression
K. John Morrow Jr., Ph.D.
|
|
Diagnostics Advancing Healthcare Reform
John F. Wong, Ph.D.
|
|
Protecting Inventions in the U.S. and Europe
Courtenay C. Brinckerhoff
|
|
“MAP” for Improving Drug Testing
John J. Pippin, M.D.
|
|
Stabilizing Protein-Folding Conformations
Gene W. Lee, Ph.D.
|
|
Versatile, Label-Free Microarray Analysis
Voula Kodoyianni, Ph.D.
|
|
Tool Firms Set Up to Defy Economic Downturn
John L. Sullivan
|
|
| February 15, 2008 (Vol. 28, No. 4) |
|
Increasing Specificity in Transporter Assays
Ismael Hidalgo, Ph.D.
|
|
Pediatric Market Offers Multiple Opportunities
Bruce Carlson
|
|
Automating Clone Picking in Bioproduction
Susan Aldridge, Ph.D.
|
|
BrainCells Bets on Small Molecule Therapies
Ilene Schneider
|
|
LC Applications Are Expanding
Angelo DePalma, Ph.D.
|
|
Top 60 Chinese Biofirms Propel Industry Forward
Eliza Yibing Zhou
|
|
Lab-Asset Management Gets Smarter
Gail Dutton
|
|
Improving Service-Provider Performance
Michael Webster
|
|
Tips for Building a Core Genotyping Facility
Vicki Glaser
|
|
Novel Approaches to Engineer Antibodies
K. John Morrow Jr., Ph.D.
|
|
London Strives to Be Global Biotech Hub
Susan Aldridge, Ph.D.
|
|
Partnerships Expedite Product Advancement
Stewart Lyman, Ph.D.
|
|
Patients Shortchanged by Big Pharma
Marc-André Gagnon
|
|
Industrial Manufacturing of Plasmid DNA
Hans Huber, Ph.D. Wolfgang Buchinger, Ph.D. Josef Diewok, Ph.D. Robert Ganja Daniela Keller Jochen Urthaler, Ph.D. Roman Necina, Ph.D.
|
|
SNP Genotyping Aids Diagnostic Development
Steven Dodsworth, Ph.D.
|
|
Hastening Epitope Discovery for Vaccines
Nikolai Schwabe, Ph.D. Amanda Turner
|
|
| February 1, 2008 (Vol. 28, No. 3) |
|
Company Update: Protagen Zeroes In on Protein Therapeutics
Sophia Fox
|
|
Trubion Tackles Second-Generation mAbs
Carol Potera
|
|
GEN’s Annual Wall Street Analyst Roundup
|
|
BioMarket Trends: Phalanx of Treatments Propels Burn Market
Bruce Carlson
|
|
DNA Methylation Bolsters Cancer Research
Nina Flanagan
|
|
Winning the Contamination Control Battle
Angelo DePalma, Ph.D.
|
|
Stem Cells Advance on Multiple Fronts
Elizabeth Lipp
|
|
Driving Discovery from Inside Out
Kathy Liszewski
|
|
qPCR Poised for Prime Time
Lloyd Dunlap
|
|
New Act Endangers Long-Term Patent Validity
Beverly Lubit, Ph.D.
|
|
Firms Need to Focus on Profits
Henry I. Miller, M.D.
|
|
Streamlining Gene Delivery with Microporation
MinSung Kim Neoncheol Jung, Ph.D.
|
|
Assay: Single-Molecule Sequencing Advances
Avak Kahvejian, Ph.D.
|
|
Combination Therapies Fortify Oncology Fight
Mark Hickinson, Ph.D. Nate Cosper, Ph.D.
|
|
Aiming at Easier Scale-Up in Protein Production
Brian Dalby, Ph.D. Chaoting Liu Weixing Chen, Ph.D. Henry C. Chiou, Ph.D.
|
|
Web Exclusive: GEN’s Annual Wall Street Roundup
|
|
| January 15, 2008 (Vol. 28, No. 2) |
|
Affitech Exploits Antibody Discovery Platforms
Susan Aldridge, Ph.D.
|
|
Company Update: GATC Solely Focused on Sequencing Services
Sophia Fox
|
|
Biomarket Trends: Molecular Diagnostics on the Move
Lucy J. Sannes, Ph.D.
|
|
Web Exclusive: Predicting the Future of the Bioreactor
Vijay Singh, Ph.D.
|
|
Tech Focus: Prognosticating the Future of the Bioreactor
Vijay Singh, Ph.D.
|
|
Turning Targets into Drug Products
Gail Dutton
|
|
Time-Resolved FRET Gains in Popularity
Kate Marusina, Ph.D.
|
|
Biobanking Needs More Standardized Procedures
Elizabeth Lipp
|
|
RNAi Gene Silencing Applications Advance
Vicki Glaser
|
|
Capitalizing on Biomarker Discovery Work
Trevor Stokes
|
|
Jump-Starting Bioprocessing Sector in U.K.
Susan Aldridge, Ph.D.
|
|
Changing Needs Drive the Media Market
Angelo DePalma, Ph.D.
|
|
Revamping Recovery & Purification Strategies
K. John Morrow Jr., Ph.D.
|
|
Improving Protection of Trial Participants
Jonathan E. Rackoff, J.D. Namrata Kotwani
|
|
Optimizing the Rapid Production of Vaccines
Silke Fetzer
|
|
Establishment of a Sustainable Biobank
Steve Arsenault Kerri McWeeny Denis Bilodeau Daniel Gaudet, M.D., Ph.D.
|
|
Novel Platform Enables Shotgun Proteomics
Brian M. Balgley, Ph.D. Cheng S. Lee, Ph.D.
|
|
Assay: Hybrid Bridges the Microplate Reader Gap
Mickie Henshall Paul Held, Ph.D.
|
|
| January 1, 2008 (Vol. 28, No. 1) |
|
Expanding Antibody Therapeutic Options
Carol Potera
|
|
BioMarket Trends: Orphan Drug Arena Driven by Biologics
Syamala Ariyanchira, Ph.D.
|
|
Tech Note: Delivery of Functional Proteins Inside Cells
Laurent Meunier, Ph.D. Stephane Moutard, Ph.D. Olivier Zelphati, Ph.D.
|
|
Addressing Unmet Type 2 Diabetes Needs
Allan B. Haberman, Ph.D.
|
|
Siemens’ Science and Technology Awards
|
|
Getting a Handle on Nanobiotech Products
Vicki Brower
|
|
High-Content Discovery Analysis
Kathy Liszewski
|
|
Repositioning Idle Drugs via Systematic Serendipity
Gail Dutton
|
|
Systems Biology Alters Drug Development
Nina Flanagan
|
|
Unlocking the Secrets of Protein Profiling
Elizabeth Lipp
|
|
Complex Peptides Challenge Manufacturers
Vicki Glaser
|
|
DTC Campaigns Mislead Public
Karina L. Brierley Ellen T. Matloff
|
|
Assay: Mimicking Cellular Behavior in Capillaries
Kate Fitzgerald, Ph.D.
|
|
Total RNA Purification for Real-Time RT-PCR
Jasmin Gibson Ken Doyle, Ph.D. Julie Kramer
|
|
Integrity Testing of Large-Size Filter Systems
Matthew Daley Jibin Hao
|
|
Making Personalized Medicine a Reality
Lisa A. Haile, J.D., Ph.D.
|
|
| December 1, 2007 (Vol. 27, No. 21) |
|
Novozymes Tackles Ingredient Manufacture
Carol Potera
|
|
Biomarket Trends: LIMS Growth Driven by Replacement Purchases
Jonathan Witonsky
|
|
Biotech Aims High in the Lone Star State
Vicki Brower
|
|
Erecting Exclusivity Barriers with Innovation
Douglas Martin, M.D.
|
|
Finding Your Place as an Industry Scientist
Tamara Zemlo, Ph.D.
|
|
ADMET Issues Slow Discovery
Elizabeth Lipp
|
|
Sample Storage Requires Regular Tweaking
Nina Flanagan
|
|
Broadening Genetic Tests in the Consumer Market
Kate Marusina, Ph.D.
|
|
Obstacles to Exploitation of miRNA Falling
Catherine Shaffer
|
|
Lyophilization Advances Improve Recovery
K. John Morrow Jr., Ph.D.
|
|
Enlisting CROs for Clinical Trial Assistance
Gail Dutton
|
|
Patent Ambushing Sullies Standard Setting
Wim Nauwelaerts
|
|
Antisocial Bio-Activism
Henry I. Miller, M.D.
|
|
High-Performance Melting Curve Analysis
Michael Hoffmann Jochen Hurlebaus Christian Weilke
|
|
Assay: Analyzing Lipid-Modifying Enzymes
Jonas Ekblom, Ph.D. Jun Wu, Ph.D. Jeff Koehler, Ph.D. Elizabeth Rietz
|
|
Optimization of Electroporation Parameters
Natascha Weiss Wolfgang Bielke, Ph.D. Peter Hahn, Ph.D.
|
|
Planning and Designing Biopharma Plants
Karin Koller
|
|
Industry on Target for a Successful Year
G.Steven Burrill
|
|
| November 15, 2007 (Vol. 27, No. 20) |
|
Invitrogen Taps Into Cell Biology Expertise
Carol Potera
|
|
BioMarket Trends: Application of RFID Can Save Time and Money
Bruce Carlson
|
|
Letter to the Editor: What About Tysabri as an MS Treatment?
|
|
Eurofins MWG Consolidates Companies' Offerings
Sophia Fox
|
|
Improved Screening for Better Lead Generation
Lloyd Dunlap
|
|
Getting a Handle on Signal Transduction
Kathy Liszewski
|
|
Seeking the Big Picture with Microarrays
Gail Dutton
|
|
Innovations in Membrane Filtration Tools
Angelo DePalma, Ph.D.
|
|
Advancing Cancer Vaccines
Sue Pearson, Ph.D.
|
|
Army Hospital Reborn as Bioscience Park
Carol Potera
|
|
Sizing Up Genzyme's Takeover Potential
|
|
Subsidizing Biofuels Is Not the Answer
William K. Jaeger, Ph.D.
|
|
Characterizing Stable Protein Formulations
Sigrid Kuebler
|
|
TF Profiling in Drug Discovery
Fiona Coats, Ph.D. James Lazar, Ph.D. Sherry Challberg, Ph.D.
|
|
ApplicationNote: Dendritic Cell-Based Immunotherapeutics
Fred Miesowicz, Ph.D.
|
|
Enhancing Performance in Cell Culture
James Babcock, Ph.D. Shawn Smith Hans Huttinga Debra Merrill
|
|
| November 1, 2007 (Vol. 27, No. 19) |
|
Millipore's Acquisitions Enhance Offerings
Carol Potera
|
|
BioMarket Trends: Liquid Chromatography Market Proliferates
Shankar Sellappan, Ph.D.
|
|
Leveraging Impact of Biodefense Contracts
Gail Dutton
|
|
Fragment-Based Discovery in Spotlight
Elizabeth Lipp
|
|
Pushing Toward a $1,000 Genome
Vicki Glaser
|
|
Use of LC Grows in MS Sample Prep
K. John Morrow Jr., Ph.D.
|
|
Weighing In On Genetic Testing & Research
Joan Zimmerman
|
|
Boosting Use of Microbial Systems in Manufacturing
Sue Pearson, Ph.D.
|
|
New Approaches Push Antibodies Ahead
Nina Flanagan
|
|
Defining Bench to Bedside Success
Lynn Sutherland
|
|
Tough Road for Biotech Patent Prosecution
Fangli Chen, Ph.D., J.D. Brian A. Fairchild, Ph.D.
|
|
POINT OF VIEW: Genetically Modified Foods Unsafe? Evidence that Links GM Foods to Allergic Responses Mounts
Jeffrey M. Smith
|
|
ApplicationNote: New Tool Refines Tissue Homogenization
Hong Gao Stephanie Thompson Romain Verollet Antonin Duval
|
|
Removing Entrenched Bottlenecks in HCS
Mark A. Collins, Ph.D.
|
|
Assay: Measurement of Mitochondrial Function
David Ferrick Steve Chomicz Min Wu
|
|
Characterizing Culture Process Dynamics
Geoffrey Esteban
|
|
Tackling Financing Challenges in Biotech
Ron Cohen, M.D.
|
|
| October 15, 2007 (Vol. 27, No. 18) |
|
HPLC Column Provider Expands Focus
Carol Potera
|
|
Application of Real-Time qPCR Broadens
Vicki Glaser
|
|
Disease Pathway Analysis
Joan Zimmerman
|
|
Reducing Attrition with Image Analysis
Susan Aldridge, Ph.D.
|
|
Overcoming Size Concerns in Cell Culture
Angelo DePalma, Ph.D.
|
|
Biologics Force Changes in Stability Testing
Gail Dutton
|
|
China Expanding Bioresearch Activities
Vicki Glaser
|
|
ServiceNote: Human Tissue Research for Drug Discovery
Amanda J. Woodrooffe, Ph.D. Robert A. Coleman, Ph.D.
|
|
BioMarket Trends: Process Improvements Bolster Peptide Drug Market
Ramin Saberi Anil Sehgal, Ph.D.
|
|
Ventana Says Its Is Worth More Than $3B
Querida Anderson
|
|
Preparedness for Bioterrorism
Rae Lyn Burke, Ph.D.
|
|
Making RNA More Durable at Room Temp
Sharron Ohgi
|
|
Application Note: Continuous Cell Profiling Technology
Elke Thedinga, Ph.D. Michael Schulze, Ph.D.
|
|
Assay: New Substrates for FRET-Based Assays
Vera Rakhmanova, Ph.D. Rich Meyer, Ph.D. Xiaohe Tong
|
|
Microbe Expression Requires Flexibility
Bo Kara Ian Hodgson
|
|
| October 1, 2007 (Vol. 27, No. 17) |
|
Alpha Biologics Takes Global Approach
Sophia Fox
|
|
Revamping Drug Discovery Strategies
Patricia F. Dimond, Ph.D.
|
|
Cytometry Drives New Business Models
K. John Morrow Jr., Ph.D.
|
|
Personalized Medicine Seeks Mainstream
Elizabeth Lipp
|
|
CMOs Focused on Meeting Needs and Time Lines
William Downey
|
|
Producing Biologics Less Expensively
Sue Pearson, Ph.D.
|
|
Transforming Healthcare With Stem Cells
Susan Aldridge, Ph.D.
|
|
Benefits Point Biotech Firms to Buffalo
Vicki Brower
|
|
Biomarket Trends: Four Therapies Dominate MS Treatment
Melissa Elder
|
|
IP May Be a Tonic for Distressed Companies
Ronald S. Gellert Gregory J. Urbanchuk
|
|
Risk-Averse Behavior Entrenched at FDA
Henry I. Miller, M.D.
|
|
Automated Target Preparation Solution
Zhu Zhu Handy Yowanto, Ph.D. Keith Roby
|
|
Assay: Validating Biomarkers with VeraCode
Mickie Henshall Elliott Gorfain
|
|
Application Note: High-Throughput Process Development
H.Brett Schreyer Scott E. Miller Seth Rodgers
|
|
Use of Perfusion Technology on the Rise
Bruce Jon Compton, Ph.D. Jacob Peter Jensen
|
|
Ways to Address Neglected Disease Issue
Cecilia Chan
|
|
| September 15, 2007 (Vol. 27, No. 16) |
|
Start-Up Firm Touts Mid-Stage Pipeline
Carol Potera
|
|
Biomarket Trends: Proteomics Sample-Prep Market Is Ripening
Jonathan Witonsky
|
|
Application Note: Strategies for the Culture of CHO-S Cells
Kevin A. Auton, Ph.D. Julie A. Bick, Ph.D. Ian M. Taylor, Ph.D.
|
|
The Game Plan for Sigma's Research Biotech
|
|
Expediting Biomarker Advances
Joan Zimmerman
|
|
Ways to Arm Antibodies Under Increasing Scrutiny
K. John Morrow Jr., Ph.D.
|
|
Capitalizing on microRNA Expression
Kathy Liszewski
|
|
Moving Biotechnology Forward with PAT
Susan Aldridge, Ph.D.
|
|
Disposables Reach Out to New Markets
Nina Flanagan
|
|
Flanders Striving to Attract Biotechnology
Querida Anderson
|
|
Pfizer Deal Pulls Xoma Out of August Slump
Querida Anderson
|
|
Too Many Mice, Too Few Pathologists
Robert D. Cardiff, MD, Ph.D. Bruce W. Altrock, Ph.D.
|
|
New Kit Facilitates Small RNA Cloning
Eric J. Devor, Ph.D.
|
|
Assay: Laser-Scanning Cytometry in Oncology
Paul Wylie, Ph.D.
|
|
Cultivating Anchorage-Dependent Cells
Jose Castillo Steven Vanhamel
|
|
| September 1, 2007 (Vol. 27, No. 15) |
|
Corning Targets Screening & Cell Growth
Carol Potera
|
|
Biomarket Trends: Pharmaceutical Industry Undergoing Transformation
Steve Arlington Anthony Farino
|
|
Operating Costs for Regional Clusters
John H. Boyd
|
|
Malaysian Gov't Fosters Biotech Growth
Robert Yuan, Ph.D.
|
|
Accelerator MS Is a Powerful New Tool
Kate Marusina, Ph.D.
|
|
Advancing Most Promising Compounds
Elizabeth Lipp
|
|
Use and Support of Forensics Flourishes
Gail Dutton
|
|
Transforming Transfection Technology
Patricia F. Dimond, Ph.D.
|
|
Process Analytics Remains Elusive Goal
Angelo DePalma, Ph.D.
|
|
Techniques to Ramp Up Protein Purification
Vicki Glaser
|
|
Stem Cell Firms Struggle for Financing
Gail Dutton
|
|
Molecular Imaging in Drug Development
Amit Agarwal
|
|
Biopharmaceutical IP Protection in China
Susan B. Fentress
|
|
Is Biomass the New Texas Tea?
Peter C. Lauro
|
|
Amplification of RNA from FFPE Tissues
Paul Siebert, Ph.D.
|
|
Ligand Enrichment and Profiling Method
Lyle Rice, Ph.D. Debra Cen, Ph.D.
|
|
Combating Mycoplasmal Contamination
Claire Scholfield, Ph.D. Anne Cox, Ph.D. Anthony Pitt, Ph.D.
|
|
VC Funding Trends for Life Science Firms
Robert Dellenbach
|
|
| August 1, 2007 (Vol. 27, No. 14) |
|
Thermo Fisher Targets Lab Solutions
Carol Potera
|
|
Biomarket Trends: Pain Therapeutics Sector Ripe with Potential
Ken Rubenstein, Ph.D.
|
|
Company Update: Engineering Solutions for Drug Discovery
Susan Aldridge, Ph.D.
|
|
Application Note: Internalization and Protein Relocation
Andreas Brecht, Ph.D Olivier Roumanie, Ph.D. Kathrin Muntener, Ph.D.
|
|
Using AMDE Data to Cut Drug Toxicology Failures
Gail Dutton
|
|
Cell-Based Research Gains Momentum
Elizabeth Lipp
|
|
Effective Optimization: Fight or Flight?
Lloyd Dunlap
|
|
Biomarkers Transform R&D
Kate Marusina, Ph.D.
|
|
Improving Protein Production Processes
K. John Morrow Jr., Ph.D.
|
|
Nurturing Growth of mAb Therapeutics
Catherine Shaffer
|
|
Demand Strong for Upstream Systems
Vicki Glaser
|
|
Strategies for Ensuring Optimal Scale-up
Angelo DePalma, Ph.D.
|
|
Trends in Mass Spec: Understanding a Drug's Metabolic Profile
K. John Morrow Jr., Ph.D.
|
|
Trends in Mass Spec: Roundtable Discussion on MS Analysis
|
|
Quest Continues for Innovations in HPLC
Susan Aldridge, Ph.D.
|
|
USPTO Rejects WARF's ESC Patents
Lisa A. Haile, J.D., Ph.D. Stacy Taylor
|
|
War on Cancer Is Being Oversold
Ralph W. Moss, Ph.D.
|
|
Debunking Downstream Bottleneck Myth
Gunter Jagschies, Ph.D. Ann O'Hara
|
|
Animal Models for Clinical Advancement
Colleen Jonsson, Ph.D.
|
|
Assay Tutorial: Engineering Lab-Friendly Lipid Assays
Paul Neilsen, Ph.D. Colin Ferguson, Ph.D. James Thompson Angie M. Branch Andy Miller
|
|
Biotech Investing a Marathon Not a Sprint
Rod Raynovich
|
|
| July 1, 2007 (Vol. 27, No. 13) |
|
Goodwin Biotechnology Expands to India
Carol Potera
|
|
Biomarket Trends: A Myriad of Approaches Fosters Growth in Early Tox Testing
Steven Heffner
|
|
Screening Technologies & Enabling Instrumentation
K. John Morrow Jr., Ph.D.
|
|
Magnetic Beads for Biomarker Discovery
Nina Flanagan
|
|
Whole Genome Amplification Strategies
Elizabeth Lipp
|
|
Increasing Capacity for GMP Peptides
Vicki Glaser
|
|
Designing Better Purification Schemes
Angelo DePalma, Ph.D.
|
|
CROs Cut Costs for Biotechs
Kathy Liszewski
|
|
Transforming Information into Knowledge
Gail Dutton
|
|
Technote: Addressing Trace Protein Detection
David Hammond, Ph.D.
|
|
KSR: A Bump in the Road for Biotech?
Courtenay C. Brinckerhoff
|
|
Biotech Business Model Thrives
J. Leslie Glick, Ph.D.
|
|
Disposable Mixing System Applications
Annemarie Braun George Oulundsen
|
|
Parallel Glycoprotein N-glycan Analysis
Nico Callewaert, Ph.D. Steven Geysens, Ph.D. Wouter Laroy, Ph.D.
|
|
Multiplexed Gene-Expression Assays
William Radany, Ph.D.
|
|
Assay: Achieving High-Throughput Mass Spec
Can C. Ozbal, Ph.D.
|
|
Assessing the Life Sciences Tool Market
Arshad Ahmed
|
|
| June 15, 2007 (Vol. 27, No. 12) |
|
Nereus Prospects Oceans for Cancer Drugs
Carol Potera
|
|
Opening the Gates on Ion Channel Drugs
Kathy Liszewski
|
|
Reducing Attrition in Late-Stage Development
Susan Aldridge, Ph.D.
|
|
Multiplexing Methods Head to Clinic
Kate Marusina, Ph.D.
|
|
Improving Drugs with Protein Engineering
Trevor Stokes
|
|
Managing Cell-Line Optimization Process
Gail Dutton
|
|
Achieving Better Isolation of Nucleic Acids
Lloyd Dunlap
|
|
China Cultivates Its Healthcare Industry
Robert Yuan, Ph.D.
|
|
BioMarket Trends: Genomics & Impending Market Revolutions
Jonathan Witonsky
|
|
OSI Pharma Needs to Expand Pipeline
Querida Anderson
|
|
Genetic Diagnosis and Wrongful Life
Kevin Costello
|
|
Array Tape for Miniaturized Genotyping
Elaine May, MD
|
|
Magnetic Bead-Based Sample Preparation
Arja Lamberg, Ph.D.
|
|
Identification of High-Producing Clones
Michael Wathen, Ph.D. Bradley Dalton Mark Gerber, Ph.D. Kevin J. Kayser, Ph.D. James S. Ross Matthew V. Caple
|
|
| June 1, 2007 (Vol. 27, No. 11) |
|
Lentiviral Vector Assists Gene Therapy
Carol Potera
|
|
Biomanufacturing in Limelight
Susan Aldridge, Ph.D.
|
|
DNA Chips Provide Key to Human Genome Analysis
Nina Flanagan
|
|
Cellulosic Biofuels Abound with Promise
Gail Dutton
|
|
Advances in Structure-Based Drug Design
Elizabeth Lipp
|
|
miRNA Becoming a Research Priority
Catherine Shaffer
|
|
SPR Expands the Knowledge of Proteins
Gail Dutton
|
|
Streamlining HPLC in Bioproduction
Angelo DePalma, Ph.D.
|
|
BIO 2007 Challenges Attendees to Innovate
Ilene Schneider
|
|
Long-Term Time-Lapse Studies Focus on Cells
|
|
BioMarket Trends: Diabetes Market Opportunities Soaring
Steven Heffner
|
|
Company Update: Ludesi Proffers Software and Services
Sophia Fox
|
|
Offshoring Your Intellectual Property
Bart Bassett Sergio Garcia
|
|
Follow-On Biologics Policy Needs Science
Henry I. Miller, M.D.
|
|
Mass Spectrometry for Metabolomics
Steve Fischer
|
|
Assay: 3-D Cell Colony Assays for HTS Studies
Steven C. Miller, Ph.D. Evan F. Cromwell
|
|
Biopharmaceutical Purification Strategies
Pranavan Thillaivinayagalingam Eli Keshavarz-Moore
|
|
Biopharma Sector Leadership in Transition
Benjamin J. Conway
|
|
| May 15, 2007 (Vol. 27, No. 10) |
|
CVBT Banks on Fibroblast Growth Factor
Carol Potera
|
|
Kinase Assays' Therapeutic Potential
Lloyd Dunlap
|
|
Development of Peptide Drugs Advances Briskly
Gail Dutton
|
|
miRNA's Role Rises in Drug Research
Kathy Liszewski
|
|
Mass Spec Protein Analysis Strategies
K. John Morrow Jr., Ph.D.
|
|
Improving Yields in Oligo Manufacturing
Vicki Glaser
|
|
Probing the Biology of Cancer Stem Cells
John F. Wong, Ph.D.
|
|
Pharmacovigilance Impacts Drug Safety
Mike Mentasana
|
|
BioMarket Trends: The Future of Genome Synthesis and Design
Rob Carlson, Ph.D. Jim Newcomb Steven Aldrich
|
|
Sangamo Poised to Earn Steady Revenues
Querida Anderson
|
|
Drug Delivery Fuels Specialty Pharma
Felix Theeuwes
|
|
Toxicogenomics for Compound Selection
Megan Laurance, Ph.D. Brigitte Ganter, Ph.D.
|
|
Assay: Cytotoxic Cell Effector Function Studies
Lisa B. English, Ph.D. Katherine Gillis Dianne Fishwild
|
|
Affinity Tagging for Protein Purification
Lee Olech
|
|
| May 1, 2007 (Vol. 27, No. 9) |
|
Improving Pharma Process Operations
Sophia Fox
|
|
Company Update: Blue Gene Tackles Disease and Migration
Carol Potera
|
|
Biomarket Trends: Cell Culture Landscape Changes Rapidly
Steven Heffner
|
|
China Looks to Accelerate Globalization
Robert Yuan, Ph.D.
|
|
So, You Want to Be a Millionaire?
Gail Dutton
|
|
Navigating Complex Pathways in Cancer
Elizabeth Lipp
|
|
Building Better Pipelines with ADME-Tox
Vicki Glaser
|
|
Molecular Diagnostics Revamps Drug Development
Kate Marusina, Ph.D.
|
|
Protein Characterization Entering New Era
Nina Flanagan
|
|
Optimized Facility Design and Utilization
Angelo DePalma, Ph.D.
|
|
BioSimilars Market Ripe for Expansion
Sue Pearson, Ph.D.
|
|
Gene Patents Jeopardize Genetic Testing
Roger Klein, MD, JD
|
|
Curing Cancer: Running on Vapor
Mike Mentasana Phillip J. Baird, M.D., Ph.D.
|
|
Assay Tutorial: Side-Effect Database for Reducing Toxicity
Ming Liu, Ph.D. Hao Chen, Ph.D.
|
|
Precision Nanoliter Aqueous Transfer
Jean Shieh Siobhan Pickett Joseph Olechno
|
|
HCDF as a Protein Labeling Methodology
Sebastian Fiedler Christof Knocke Jennefer Vogt Harmut Oschkinat Anne Diehl
|
|
| April 15, 2007 (Vol. 27, No. 8) |
|
SynCo Bio Partners Is Poised for Expansion
Carol Potera
|
|
Biomarket Trends: Shape of RNAi Screening Is Changing Rapidly
Jonathan Witonsky
|
|
Company Update: Banking on Human Embryonic Stem Cells
|
|
Folding@home Adopts PlayStation 3
|
|
Companies Step Up to GPCR Challenge
Susan Aldridge, Ph.D.
|
|
Entering the Promising World of Metabolomics
Gail Dutton
|
|
Harnessing RNAi's Gene-Silencing Power
Kathy Liszewski
|
|
Techniques for Characterizing Biologics
Aicha Otmani, Ph.D. Fenton Fong
|
|
Enterprising Polymer Delivery Methods
Vicki Brower
|
|
Pharmaceutical Operations Expand in China
Robert Yuan, Ph.D.
|
|
Biosimilars Jumpstart Biotech in India
Nalini Motwani, Ph.D.
|
|
Moving Immunology Research Forward
Alan Koop
|
|
Acadias CNS Pipeline Propels Growth
Querida Anderson
|
|
Searching for Viable Biobusiness Models
Gary P. Pisano, Ph.D.
|
|
Nuclear Imaging Drug Development Tools
Lynn Buchanan, Ph.D. Paul Jurek, Ph.D. Russ Redshaw
|
|
Assay: Miniaturizing GPCR-Signaling Studies
Sarah Schultz Tracy Worzella
|
|
Large-Scale Affinity Chromatography
Frank Detmers Pim Hermans Mark ten Haaft
|
|
| April 1, 2007 (Vol. 27, No. 7) |
|
Acceleron Takes on Bone & Muscle Repair
Carol Potera
|
|
Company Update: GE Cultivates Its Life Sciences Business
Carol Potera
|
|
BioMarket Trends: Promises and Challenges of Pharmacogenetics
Harry Glorikian
|
|
Technote: The State of Microsample Quantitation
David Ash Philippe Desjardins
|
|
Advances in Epitope Tagging Strategies
K. John Morrow Jr., Ph.D.
|
|
CGH for Detecting Copy Number Variation
Vicki Glaser
|
|
Designing Out Up-& Downstream Mismatches
Angelo DePalma, Ph.D.
|
|
Combating Ocular Disease
Elizabeth Lipp
|
|
Regenerative Medicine Enters Realm of Reality
Nina Flanagan
|
|
Keeping an Eye on Rising Biotech Firms
Kenneth H. Buetow, Ph.D.
|
|
Streamlining Biomarker Validation Activities
Vicki Glaser
|
|
In Defense of Gene Patenting
Geoffrey M. Karny
|
|
Glycoanalysis of Recombinant Proteins
Peter Porschewski, Ph.D. Thibault Geoui, Ph.D.
|
|
Assay: High-Throughput DNA Methylation
Peter W. Laird, Ph.D. Marina Bibikova, Ph.D. Jian-Bing Fan, Ph.D.
|
|
Improving Quality in Cryopreserved Cells
John M. Baust, Ph.D. Ana Maria Pardo Todd Upton, Ph.D.
|
|
New Funding Model for Start-Ups
Barbara S. Schilberg
|
|
| March 15, 2007 (Vol. 27, No. 6) |
|
AVI Is Taking Antisense Drugs to the Clinic
Carol Potera
|
|
Biomarket Trends: Proteomics Arrays Offer Wide Applications
Jonathan Witonsky
|
|
Funding Embryonic Stem Cell Research
Sigrid Fry-Revere
|
|
Cell Signaling Pathway Analysis
Patricia F. Dimond, Ph.D.
|
|
Evaluating Data Flow in Systems Biology
Kate Marusina, Ph.D.
|
|
Chemogenomics Reveals New Synergies
Kathy Liszewski
|
|
Protein Microarray Market Scope Broadens
Vicki Glaser
|
|
Designing & Running Multiproduct Facilities
Gail Dutton
|
|
Ten Years After Dolly: Where Are We?
Sophia Fox
|
|
Are Kinase Inhibitors Poised for Success?
Peter Lassota Mark Roskey
|
|
Labeling Can Restore the Public's Trust
Rebecca Spector
|
|
Assay: Accuracy and Precision with Serial Dilution
Joseph W. Barco Manuel Gomez Joseph P. Karbowski Ian Yates
|
|
Multiplex Analysis of Drug Toxicity Markers
Jane Luo, Ph.D. Han-Chang Chi Michael Gary Jackson Yong Yu Kahaku Oades Patrick Pezzoli Gordon Vansant Scott Boyer
|
|
Disposable Large-Scale Pressure Sensors
Jim Furey
|
|
| March 1, 2007 (Vol. 27, No. 5) |
|
Nanoxis Focuses on Membrane Proteins
Sophia Fox
|
|
BioMarket Trends: Mass Spec Finds a Niche in Biomarkers
Justin Saeks
|
|
Company Update: Advaxis Explores New Cancer Vaccines
|
|
Automation Technologies Drive Solid-Phase Extraction
Gail Dutton
|
|
Technote: Integrated Data Access, Analysis & Support
Kathleen Mensler
|
|
qPCR Methods Are Continuing to Evolve
Nina Flanagan
|
|
Safety/Toxicity Issues in Drug Discovery
Elizabeth Lipp
|
|
Application Note: Column-Free Solutions For Purification
Bruce W. Jarvis, Ph.D. Haiyang Gruenwald, Ph.D.
|
|
Novel Methodologies Allow Greater Accessibility to qPCR
Nicholas D. Rose
|
|
Strategic Protein Production
K. John Morrow Jr., Ph.D.
|
|
Formulation: One Ingredient for Success
Angelo DePalma, Ph.D.
|
|
China Pharma Basking In Its Spotlight
Eliza Yibing Zhou
|
|
Biotech Has Larger Role in Providing Clean Energy
Susan Aldridge, Ph.D.
|
|
Supplement Article: RT-PCR Enters the Realm of Stochastic Gene Expression
|
|
Licensees May Be Gaining a New Legal Weapon
Richard B. Smith
|
|
Labeling Cloned Food Is Unnecessary
Henry I. Miller, M.D.
|
|
Quantifying Changes in Cellular Energetics
David Ferrick, Ph.D. Andy Neilson Min Wu, Ph.D. Steve Chomicz
|
|
Assay: Optimizing RT-PCR for Pathogen Detection
Steve Harrison Graham Lidgard, Ph.D.
|
|
Host Strain Development for Proteins
Diane M. Retallack Charles H. Squires
|
|
Late-Stage Cancer Vaccines Set to Launch
|
|
| February 15, 2007 (Vol. 27, No. 4) |
|
Bioengineering Bacteria for Drug Delivery
Carol Potera
|
|
BioMarket Trends: Diagnostic Tools Change Cancer Treatment
Harry Glorikian
|
|
Role Grows for HPLC in Discovery
Kathy Liszewski
|
|
Label-Free Biosensors Show Early Promise
K. John Morrow Jr., Ph.D.
|
|
New Methods Get SNPs Closer to Clinic
Trevor Stokes
|
|
Regulation Shifts from Product to Process
Vicki Glaser
|
|
Optimizing Antibody Biomanufacture
K. John Morrow Jr., Ph.D.
|
|
Techniques for Cell Culture Improvement
Susan Aldridge, Ph.D.
|
|
Embryonic Stem Cells: Not Just From Humans
Sue Pearson, Ph.D.
|
|
Stem Cells for Discovery & Development
Susan Aldridge, Ph.D.
|
|
Laboratory Asset Management Is Thriving
Gail Dutton
|
|
Dr. Reddy's Revenues Hit the $1B Milestone
Querida Anderson
|
|
Building a Bioscience Cluster
Bill Fair
|
|
Monolithic Columns for Biomolecule Analysis
Srinivasa Rao, Ph.D. Nathan Bach, Ph.D.
|
|
Assay: Perfect Match Versus Single-Base Mismatch
Ramin Saberi
|
|
Base-Tolerant Affinity Resin for Mabs
Aman Mottaqui-Tabar
|
|
| February 1, 2007 (Vol. 27, No. 3) |
|
Aldagen Isolates Highly Active Stem Cells
Carol Potera
|
|
Biomarket Trends: Diversity Drives Use of siRNA
Tamara Zemlo, Ph.D.
|
|
Techniques to Overcome HTS Bottlenecks
Joan Zimmerman
|
|
$1,000 Genome Remains the Holiest
Kate Marusina, Ph.D.
|
|
RNAi Approaches for Target Validation
Patricia F. Dimond, Ph.D.
|
|
Disposables Win Downstream
Angelo DePalma, Ph.D.
|
|
Improving Protein Production Strategies
K. John Morrow Jr., Ph.D.
|
|
U.K. Working to Optimize Bioproduction
Susan Aldridge, Ph.D.
|
|
Diagnosis, Prognosis, and Therapy Selection
Elizabeth Lipp
|
|
Molecular Diagnostics Market Assessment
Alfred R. Doig
|
|
Puerto Rico Views Itself as a Bio Island
Carol Potera
|
|
Outsourcing Phase IV Pharma Research
|
|
GEN's Annual Wall Street Roundup
|
|
Rosalind Franklin Society Founding Board to Hold First Meeting
|
|
National Security and Scientific Research
Stephen M. Goodman
|
|
Automated Molecular Diagnostics
David H. Persing, MD, Ph.D.
|
|
Assay: High-Resolution Melting & Unlabeled Probes
Deepika deSilva Jana Blackett
|
|
Genome Analysis: Microsatellites or SNPs
Michele A. Gilson, Ph.D. Anatoli Tassis, Ph.D.
|
|
Linking Stainless and Single-Use System
John Boehm
|
|
| January 15, 2007 (Vol. 27, No. 2) |
|
Cell Therapeutics Counts on Drug Delivery
Carol Potera
|
|
BioMarket Trends: Cancer Vaccines Exhibit Potential
Bruce Carlson
|
|
Business Savvy for UK Biotechs
Susan Aldridge, Ph.D.
|
|
Making Sense of HCS Information
Lakshmi Kamath, Ph.D.
|
|
Robotic Solutions for Improved Lab Analysis
Ilene Schneider
|
|
RNAi-Based Gene Expression Manipulation
Trevor Stokes
|
|
Laser-Capture Microdissection Advances
Kathy Liszewski
|
|
Omics Prove Handy in Production Processes
Angelo DePalma, Ph.D.
|
|
Uniting Efforts in Molecular Medicine
Kenneth H. Buetow, Ph.D.
|
|
Avastin Pads Genentech's Bottom Line
Querida Anderson
|
|
Funding Challenges for Gene Therapy
Riku Rautsola, Ph.D.
|
|
Human Genome-Wide Association Studies
Tim Keith, Ph.D.
|
|
shRNAs Targeting Tumor Suppressor Genes
Diana Ji Stacy L. Deeds Edward J. Weinstein, Ph.D.
|
|
Managing Scale-Up of Recombinant Proteins
Ashley Wigley Diane Wilkinson, Ph.D. Dave Mead, Ph.D.
|
|
| January 1, 2007 (Vol. 27, No. 1) |
|
High-Resolution Oligo-Based CGH
Anniek De Witte Christopher Rizzo Francisco Cifuentes
|
|
SAFC Biosciences Expands Production
Carol Potera
|
|
BioMarket Trends: DNA Sequencing
Jonathan Witonsky
|
|
Reconstructing the Drug Discovery Pipeline
Elizabeth Lipp
|
|
Changing Game Plan for Protein Profiling
Nina Flanagan
|
|
Industrial Biotech Meets Systems Biology
Jose Manuel Otero Lisbeth Olsson, Ph.D. Jens Nielsen, Ph.D.
|
|
Serum for Cell Culture Out, Stem Cells In
Vicki Glaser
|
|
Offshoring R&D Activity
Vicki Glaser
|
|
What the New Congress Spells for Biotech
Gail Dutton
|
|
Therapeutic Cancer Vaccine Options
Sue Pearson, Ph.D.
|
|
The Basics of Patent Licensing Explained
Larry A. Roberts
|
|
Better Science Means Safer Food
Henry I. Miller, M.D.
|
|
Going Beyond Information Retrieval
Darryl Leon, Ph.D.
|
|
Novel Bioreactors for Fragile Glycoproteins
Silke Langhammer Rene Brecht, Ph.D. Uwe Marx, Ph.D.
|
|
Biotech's Changing Competitive Landscape
Viren Mehta, Pharm.D.
|
|
| December 1, 2006 (Vol. 26, No. 21) |
|
Bioanalytical Systems Targets CRO Niche
|
|
Finding and Working with a Staffing Firm
|
|
Lab Notebooks Offer Efficiency Gains
Gail Dutton
|
|
Honing in on signal Transduction Pathways
|
|
Gauging Nanobiotech's Promise Realistically
|
|
Research Drives Microscopy Innovations
Elizabeth Lipp
|
|
Collaborative Spirit Fosters Bioinformatics
|
|
Minimizing Cost and Use of Purified Water
|
|
Isolator Technologies Slowly Catching On
Angelo DePalma, Ph.D.
|
|
Marine Bioprospecting for Novel Drugs
Susan Aldridge, Ph.D.
|
|
BioMarket Trends
|
|
Abbreviated Approval of Generic Biologics
|
|
Market Research Tips for Suppliers
|
|
TechNote: Parallel Affinity-Based Sample Preparation
Matilda Almstedt Jesper Hedberg, Ph.D. Johan Ohman
|
|
Finding Modulators of the Hh Pathway
|
|
Systems Biology Tools Get Personal
|
|
Basic Considerations for Laboratory Water
|
|
Recent Growth Sets Stage for Q4 2006
|
|
| November 15, 2006 (Vol. 26, No. 20) |
|
Optimizing the Value of Potential Novel Drugs
|
|
Sample Prep Gaining Priority in Discovery
Nina Flanagan
|
|
The Next Generation of DNA Sequencing
Kate Marusina, Ph.D.
|
|
Filtration Technology Steps Up to Next Level
|
|
Product Technologies for Lyophilization
|
|
China-Grown Pharma Products
|
|
BioTime Bets on Blood Replacement
Gail Dutton
|
|
TechNote: High-Throughput DNA Extraction Solutions
|
|
Who Will Lead the Revolution?
|
|
Consistency from a Small Integrated System
|
|
Biospecimen Collection and Management
|
|
Genomic-Proteomic Cell Culture Approaches
|
|
| November 1, 2006 (Vol. 26, No. 19) |
|
GenoLogics Automates Omics for Labs
|
|
Can Pharma & Biotech Foil Counterfeiting?
Gail Dutton
|
|
Outsourcing Can Add Capacity & Expertise
|
|
Multidisciplinary Approach to RNAi
|
|
Antibody Engineering Methods Advance
|
|
Novel Vaccines Expand Potential Markets
|
|
Small Molecule Drugs
|
|
BioMarket Trends
|
|
Maximizing the Value of Biotech Patents
|
|
Biotech Production Is Blooming in the Tropics
|
|
Multiparametric Assays on Individual Cells
|
|
RNAi Libraries for Functional Genomics
|
|
Navigating the Postpreservation Viability Fog
|
|
Third Quarter Life Science Sector Review
|
|
| October 15, 2006 (Vol. 26, No. 18) |
|
BioMarket Trends
|
|
Company Update: Sequencing Technology Applications Expand
|
|
Maximizing Discovery Using Kinase
|
|
Microarrays Find their Way into the Clinic
|
|
Microrarray Standards Are the Next Step
Elizabeth Lipp
|
|
Safety Biomarkers Holy Grail of Toxicology
Kate Marusina, Ph.D.
|
|
Get Quality and Quantity in Your Process
Angelo DePalma, Ph.D.
|
|
Telemedicine Enables Better Care
|
|
Flexible Protein Microarray Inkjet Printing
|
|
Streamlining HTS for Challenging Targets
|
|
Rotating Bioreactors for Manufacturing
|
|
| October 1, 2006 (Vol. 26, No. 17) |
|
New Gene Sequencer Targets Productivity
|
|
BioMarket Trends
|
|
Inflammation Research Leads to Targets
|
|
Expanding Applications of Diagnostic Tools
|
|
Changing the Way Research Is Conducted
|
|
PCR Applications Continue to Expand
Elizabeth Lipp
|
|
New Software Tackles Mounds of Data
|
|
Bringing Pharmacogenomics into the Clinic
|
|
CMOs Aim to Boost Production Efficiency
|
|
Monoliths Seen to Revitalize Bioseparations
|
|
Connecting Basic Research and Patient Care
Susan Aldridge, Ph.D.
|
|
TechNote: Ratiometric Photometry for Calibration
|
|
Patent Rights in Biological Material
|
|
Making the Complex Simple
|
|
Isothermal Titration to Characterize Binding
|
|
Epitope Mapping and Vaccine Research
|
|
Ensuring Efficient Aeration of Cell Cultures
|
|
Life Sciences Strategic Deal-Making Trends
|
|
| September 15, 2006 (Vol. 26, No. 16) |
|
ExSAR Focuses on Discovery & Optimization
|
|
Company Update: ApoLife Touts Yeast-Based Expression System
|
|
BioMarket Trends: Biosensor Markets Outperform Expectations
|
|
European Biotechs Face a Funding Crisis
|
|
Biomolecular Screening Technologies
|
|
Maximizing Cell-Based Imaging Results
|
|
RNAi in Drug Discovery & Therapeutics
Kathy Liszewski
|
|
Bioprocess Simulations Gain Traction
Gail Dutton
|
|
Systematic Approach to Optimizing HPLC
Gail Dutton
|
|
Slow Adoption of PAT for Bioprocessing
|
|
Driving Standards in Single-Use Disposables
|
|
Preclinical R&D Investment Is Crucial to Long-Term Success
|
|
LOH and DNA Copy Number Changes
|
|
Overview of SmartFlow Tangential Flow Filtration
|
|
Minimizing Off-Target Effects in Transfection
|
|
| September 1, 2006 (Vol. 26, No. 15) |
|
ChemDiv's Collaborative CRO Relationships
|
|
Current New Drug Application Requirements
|
|
BioMarket Trends
|
|
VisualSonics Targets the Preclinical Area
|
|
Fluidics for qPCR, Diagnostics & Biodefense
|
|
Protein Crystallization in Pharma Research
Elizabeth Lipp
|
|
Diagnostics in Gene and Protein Expression
|
|
Reconfiguring Mass Spec Instrumentation
|
|
Myriad Options for Molecular Diagnostics
Gail Dutton
|
|
Post-Translational Modification Approaches
|
|
ISPE's Role in Pharma Industry's Transition
|
|
Process Monitoring On-Line & in Real-Time
Angelo DePalma, Ph.D.
|
|
Chinese Biogenerics and Protection of IP
|
|
Bringing Drugs and Devices Together
Susan Aldridge, Ph.D.
|
|
The Bioethics of IVD Devices and Informed Consent Issues
|
|
Automation of Protein Crystallography
|
|
Physiologically Relevant HTS Technologies
|
|
IntegratedProcess Design & Development
|
|
Novel Diagnostics Help Target Therapies
|
|
| August 1, 2006 (Vol. 26, No. 14) |
|
TechNote: Ca2+ Signal Detection in HTS Operations
|
|
Biomarker Discovery and Identification
|
|
Whither Steel & Glass in a Disposable Age
|
|
TechNote: Antibiotic-Free Systems for Production
|
|
Case Study: Vaccine Production Facility Built in 11 Months
|
|
Biopharmaceutical Approvals Review
|
|
GEN Innovations in Biotechnology
|
|
Company Update: Biofocus Expands its Menu of Offerings
Sophia Fox
|
|
Role of Cell-Based Assays in R&D Grows
Elizabeth Lipp
|
|
Drug Discovery: Successful Lead Optimization Strategies
Kathy Liszewski
|
|
Multidimensional Analysis Approaches
Gail Dutton
|
|
Overcoming the Critical Issues in Scale-Up
Susan Aldridge, Ph.D.
|
|
Development & Production of Antibodies
|
|
BioMarket Trends
|
|
Facilitating the Manufacturing of Oligos
Carol Potera
|
|
Monoclonal Antibody Purification with CHT
|
|
Versatile Tag for Cell-Based Screening
|
|
Novel Technique for Biomarker Discovery
|
|
German Biotechs Embrace Reverse Mergers
|
|
| July 1, 2006 (Vol. 26, No. 13) |
|
Using Biotech Tools for Plant Breeding
|
|
BioMarket Trends
|
|
Targeting Biotech Institutional Investors
|
|
Epitope Tagging Generates New Products
|
|
Protein Kinases in Signal Transduction
|
|
Range of Applications for Biomagnetics
Gail Dutton
|
|
Market Growing for Custom-Made Peptides
|
|
Antiviral Research Hits Its Stride
Elizabeth Lipp
|
|
CROs Become a Biotech Industry Staple
Susan Aldridge, Ph.D.
|
|
Spotlighting Neurobiotech Developments
|
|
Combating the R&D Productivity Decline
|
|
Disclosure Issues for Life Sciences Firms
|
|
Metrics for Economic Development
|
|
Getting More Value from Bioinformatics
|
|
Barcoding and Automated Electophoresis
|
|
New Tools Improve Bioprocess Operations
|
|
Pre-Deal Leadership Due Diligence a Must
|
|
| June 15, 2006 (Vol. 26, No. 12) |
|
Pain Therapeutics Takes Different Path
|
|
Biomarket Trends
|
|
Nucleic Acid-Based Technologies Ramp Up
|
|
Going a Label-Free Route with Biosensors
|
|
Enabling Technologies at MipTec 2006
Susan Aldridge, Ph.D.
|
|
Focus on Mid-Densities Drives Multiplex Arrays
Gail Dutton
|
|
Biomanufacturing for Regenerative Medicine
Kathy Liszewski
|
|
Disposable Bioreactors Gaining Favor
|
|
Progress Report on the NIH Roadmap Initiative
|
|
Scientific Interactions Advancing in Mid-East
|
|
Gilead Targets HIV & Bird Flu Markets
Querida Anderson
|
|
ID and Validation of Biomarkers
|
|
Cell Density and Physiology Monitoring
|
|
Assay: Parallel Approaches to Target Identification
|
|
Proteome Partitioning and Fractionation
|
|
| June 1, 2006 (Vol. 26, No. 11) |
|
Thermogenesis' Art of Cryopreservation
Kate Marusina, Ph.D.
|
|
GEN's Annual Top 20 Molecular Millionaires
|
|
Governor Says Puerto Rico Will Not Rest on Pharmaceutical Manufacturing Laurels
|
|
Chromatography Advances Drug Discovery
|
|
Trends & Expectations in Bioinformatics
|
|
Target Screening Focuses on Ion Channels
Elizabeth Lipp
|
|
SNP Genotyping Methods Surge Ahead
|
|
Maintaining Biocontamination Control
Angelo DePalma, Ph.D.
|
|
Pharmaceutical Tech Transfer in the Spotlight
Susan Aldridge, Ph.D.
|
|
Biofirms Develop Novel Therapeutics for MS
|
|
When is Private Really Public?
|
|
Marijuana, Medicine & the FDA
|
|
Protein Tomography Applications Expand
|
|
Assay Tutorial: Adenoviral Vector Gene Delivery System
|
|
Microbial and Cell Growth in Microtiter Plates
|
|
Reverse Mergers in Life Science Financing
|
|
| May 15, 2006 (Vol. 26, No. 10) |
|
eGene Transforms Genetic Analysis Field
|
|
Deviation Controls in Pharmaceutical R&D
|
|
Sample Prep Upstream of Mass Spectrometry
Vicki Glaser
|
|
Inhibiting Protein-Protein Interactions
|
|
Nonviral Approaches to DNA Delivery
Kathy Liszewski
|
|
Targeting a Multibillion-Dollar Market
Querida Anderson
|
|
Are We Being Outdone by Bacteria?
|
|
Using Isothermal Titration Calorimetry
|
|
Assay: Proteomics Technology for Plasma & Serum
|
|
Glucose Measurement for Cell Culture
|
|
| May 1, 2006 (Vol. 26, No. 9) |
|
Source MDx Advances Molecular Medicine
|
|
Former President Says Biotech Must Address Energy Needs
|
|
Advice on How to Survive the Taq Wars
|
|
ADMETox Improves Drug Discovery Rates
|
|
Systems-Based Approach Gaining Ground
Angelo DePalma, Ph.D.
|
|
Fragment-Based Drug Design Optimizes Hits
|
|
Utilizing Metabolic Profiling in Discovery
|
|
Pittcon 2006 Launches and Highlights
|
|
Surviving the Treacherous Transgenics Path
|
|
Navigating the Bench to Bedside Journey
|
|
Novel Products for Life Sciences Imaging
Susan Aldridge, Ph.D.
|
|
Analysis of a Patent Applicant's Obligations
|
|
Nanotechnology in Global Security and Economics
|
|
Surface Treatments for Fastidious Cells
|
|
Detecting MD-Associated Gene Variants
|
|
New Platform for Producing Viral Vaccines
|
|
Brave New World of Patents and Pricing
|
|
| April 15, 2006 (Vol. 26, No. 8) |
|
Chemo-Proteomics Approach to Cancer
|
|
Access to Global Networks in Life Sciences
|
|
Methods to Develop and Validate Bioassays
Kathy Liszewski
|
|
Peptide Drug Discovery Research Reenergized
|
|
Achieving Seamless RNA Analysis
|
|
Market Increases Oligonucleotide Demands
|
|
Microsoft Establishes the BioIT Alliance
|
|
Isis Moves Ahead on Antisense Program
Querida Anderson
|
|
Bridging Biological Systems Knowledge Gaps
|
|
Assay: Microfluidic Capillary Electrophoresis
|
|
Glycosylation Patterns During Fermentation
|
|
| April 1, 2006 (Vol. 26, No. 7) |
|
Genta Seeks Therapeutic Product Approval
|
|
Asian Biotech: Taiwan Seeks Successful Business Models
Robert Yuan, Ph.D.
|
|
Conference Highlights Drug Delivery Methods
|
|
Life Science Cluster Grows in London
Susan Aldridge, Ph.D.
|
|
Biotechnology's Mid-Caps Post Solid Gain
|
|
Commercial Amounts of Purine Nucleosides
Sophia Fox
|
|
Nanobiotech in Genomics and Proteomics
|
|
Taming the Genome with Microarrays
Elizabeth Lipp
|
|
Protein Characterization Applications Grow
|
|
Next-Generation Protein Characterization
Susan Aldridge, Ph.D.
|
|
Technical Note: Highly Sensitive qRT-PCR from One Cell
|
|
Lean and Six Sigma Approaches Taking Hold
Angelo DePalma, Ph.D.
|
|
Characterization of Biologicals Is Advancing
|
|
Patent Litigation: Is it Worth the Expense?
|
|
Medical Science Liaisons in Biotech
|
|
Assay: Protein Production for Structural Analysis
|
|
Streamlining Pharmacogenetic Analysis
|
|
Thermal Welding for Sterile Connections
|
|
Emerging Biopharmaceutical Companies
|
|
| March 15, 2006 (Vol. 26, No. 6) |
|
The FDA and Follow-On Biologics
|
|
Solutions for Cell-Focused Applications
Sophia Fox
|
|
Benefits of Structure-Based Drug Design
|
|
Assays for Cell Proliferation Studies
|
|
Cheminformatics for Finding New Drugs
Elizabeth Lipp
|
|
Biomarker Detection & Measurement
Kathy Liszewski
|
|
Tissue Microarrays Reach New Markets
|
|
CMOs Find Opportunities in Biologics
|
|
Multiproduct Manufacturing Facilities
|
|
Analyst Likes AEterna Long-Term
Querida Anderson
|
|
Implications of Faith-Based Science
|
|
Assay: Quantitative Multiplex Immunoassays
|
|
Improving Protein Interaction Analysis
|
|
Integrating Chirality into Manufacturing
|
|
| March 1, 2006 (Vol. 26, No. 5) |
|
Finding a Balance in Assessment of Risk
|
|
M&As as Important Development Tools
|
|
Corporate Profile: Beckman Removes Divisional Barriers
|
|
Clearing the Target Validation Bottleneck
|
|
In vivo and In vitro Techniques Help to Unclog the Drug Discovery Process
|
|
LabAutomation 2006 Final Recap
|
|
Protein Arrays as Key Discovery Tools
|
|
HPLC Undergoes Slow, Steady Evolution
Angelo DePalma, Ph.D.
|
|
QA/QC for Viral Clearance
Gail Dutton
|
|
Purification Woes Upstage Upstream Gains
|
|
ELN and LIMS Aid Biotechnology Growth
|
|
Pitfalls in Patenting of Biomolecules
|
|
Good News on Medicines but Bad Rap for Drug Makers
|
|
Achieving Low-Volume Liquid Handling
|
|
Cell-Based Assays for Study of GPCRs
|
|
Choosing & Scaling Up Right Filter Combo
|
|
M&As as Important Development Tools
|
|
| February 15, 2006 (Vol. 26, No. 4) |
|
Tracking Diseases at the Molecular Level
Sophia Fox
|
|
Metabolomics Plays Crucial Discovery Role
Kathy Liszewski
|
|
In Silico Tools Streamline Drug Design
Gail Dutton
|
|
Target Identification Methods Advance
Elizabeth Lipp
|
|
Capitalizing on Biotech Production Opportunities
Susan Aldridge, Ph.D.
|
|
Ready-to-Play Assays, Kits, and Libraries
|
|
Large-Scale Production of Antibodies
|
|
CancerVax' Stock Rises with Merger
|
|
In Support of Animal Study Management Software
|
|
Assay: Miniaturized Cellular Assays
|
|
Next-Generation RNA Interference
|
|
Optimizing Bacterial Cell Processing
|
|
| February 1, 2006 (Vol. 26, No. 3) |
|
Biolog Advances Global Cell Analysis Scans
|
|
Drug Discovery and Development in India
|
|
Extracting Compounds for Diverse Disciplines
|
|
Technical Note: Relieving the HTS Bottleneck for Kinases
|
|
Optimizing High-Throughput Screening
|
|
Improving Gene Expression Analysis
|
|
Bright Sky for Single-Use Bioprocess Products
Angelo DePalma, Ph.D.
|
|
Scientific Misconduct: Risks to Biotechnology
|
|
Wake-up Call for U.S. Innovation
|
|
Planning, Documentation, and Collaboration
|
|
Multiplex Transcription Factor Profiling
|
|
Testing & Validation of Disposable Systems
|
|
| January 15, 2006 (Vol. 26, No. 2) |
|
New York City Pursues Biotechnology Dream
|
|
State of Industry Discussed at BIO-Europe
Susan Aldridge, Ph.D.
|
|
Licensing & Collaborations for Tamiflu Patent
Gail Dutton
|
|
DeveloGen Tackles Metabolic Disorders
Sophia Fox
|
|
Cellular Analysis via High Content Screens
Elizabeth Lipp
|
|
Improving Stability While Adding Value
Angelo DePalma, Ph.D.
|
|
Development of Stem Cell Technologies
|
|
New Biomolecules for Cancer Treatment
|
|
French Biotech on the Upturn
|
|
Corporate Partnering Status Report
|
|
Steps for Preventing the Misuse of Biological Research
|
|
Proteomics-Based Biomarker & Drug Discovery
|
|
Assay: Protein Microarrays on Nitrocellulose Slides
|
|
Embryonic Stem Cell Research Operations
|
|
| January 1, 2006 (Vol. 26, No. 1) |
|
Biopartnering Crucial to Survival in Europe
Susan Aldridge, Ph.D.
|
|
Establishing QC for Molecular Diagnostics
|
|
Measurement of a Communications Program
|
|
New Tools Highlighted at ASHG Conference
|
|
Protein Profiling Poised to Make its Mark
Angelo DePalma, Ph.D.
|
|
Correlating Genomics, Race, and Medicine
Gail Dutton
|
|
French Biotech Hungers for Fiscal Stimuli
|
|
Applying Biomarker Discovery Strategies
|
|
RNAi Technologies Become Discovery Staple
|
|
Toxicogenomics Enhances Drug Discovery
Kathy Liszewski
|
|
Downstream Processing Needs a Boost
Susan Aldridge, Ph.D.
|
|
Cell Culture Advances Enable Better Biology
|
|
BioMarket Trends: Cell Culture Arena Fueled by Emerging Variety of Biologic Therapeutics
|
|
Gene Patents and Global Competition Issues
|
|
Policymakers Should Harness User Fees for Drug Safety
|
|
Effective GPCR Screening Using ERK 1/2
|
|
Maximizing Quality in HTS Kinase Screening
|
|
Taking the Guesswork Out of Production
|
|
| December 1, 2005 (Vol. 25, No. 21) |
|
Mobilizing Nanomedicine Technologies
|
|
Industry Analysis of Discovery Informatics
|
|
Employment Trends in the Biotech Industry
|
|
High Purity Water: Combating Contamination
Gail Dutton
|
|
Protein Microarrays
|
|
Fluoresence & Bioluminescence Enlighten R&D
|
|
Strategies to Move Beyond Target Validation
|
|
Biosimilars Shake up the Biologics Market
|
|
Taiwan Industry Puts Strong Focus on Biotech
|
|
PTO Utility Guidelines Receive Stamp of Approval
|
|
Designing an Effective Preclinical Profiling Strategy
|
|
Simplified Development of FRET Assays
|
|
Using Multi-Pathway Target Knockdown
|
|
Parenteral Packaging Concerns for Drugs
|
|
Biotech Posts Impressive Third Quarter Results
|
|
| November 15, 2005 (Vol. 25, No. 20) |
|
The FDA Inspection Process as a Learning Tool
|
|
Tissue Models Boost Drug Discovery Efforts
|
|
Scotland Pursues Stem Cell Excellence
|
|
Chiral Chemistry Aids Drug Development
Gail Dutton
|
|
Advancing Viral Vector-Based Technology
|
|
Resilience Challenged and in Short Supply in Our Society
|
|
Protein Identification and Quantification
|
|
Platforms for Eicosanoid Measurements
|
|
Optimizing Your Process Unit Operations
|
|
| November 1, 2005 (Vol. 25, No. 19) |
|
Emerging Technologies for Ion Channels
|
|
Challenges Remain for Antibody Products
|
|
A New Spin on Plasma Biomarker Discovery
|
|
Commercial Bioactivities in Western Canada
|
|
Patent Rights and Pharmaceutical Reimportation
|
|
Bridging the Gap between Model Systems and Human Biology
|
|
Electronic Laboratory Notebook Systems
|
|
Purification for Demanding Applications in Life Sciences
|
|
The Shrinking Biomanufacturing Facility
|
|
How to Improve Series B-Round Valuations
|
|
| October 15, 2005 (Vol. 25, No. 18) |
|
Review of FDA Guidance on Risk Management
|
|
Molecular Diagnostics as Clinical Tools
Gail Dutton
|
|
Blue Biotech Puts Norway on the Map
Susan Aldridge, Ph.D.
|
|
Whole Genome Amplification Technologies
Mary Addonizio
|
|
Novel Systems for Visualizing Biological Data
Kathy Liszewski
|
|
Singapore Attracts Life Science Companies
|
|
The State of BSE Surveillance Efforts in the United States
|
|
Optimized Solutions for RNAi Experiments
|
|
Utilizing Rapid Point-of-Use Protein Assays
|
|
Recipe for Ensuring Process Control Success
|
|
GEN's Spotlight on Wall Street News
|
|
| October 1, 2005 (Vol. 25, No. 17) |
|
Contract Manufacturing Fills Industry Niche
|
|
Linking Discovery Data to Diagnostics
Elizabeth Lipp
|
|
GEN Talks with President Bill Clinton
|
|
Biotechnology in Australia and New Zealand
|
|
Nucleic Acid Purification Takes Many Forms
Ilene Schneider
|
|
Manipulation and Analysis of Nucleic Acids
|
|
A Step Forward for Biotechnology Patent Law
|
|
Proposition for a New and Better Model for Healthcare
|
|
Achieving Optimal Yields of High Quality RNA
|
|
How do Bacteria Turn Their Genes On and Off?
|
|
Nanoscale Gradient Chromatography for LC-MS
|
|
Manufacturing of Biopharmaceutical Proteins
|
|
Diabetes: Potential Breakthroughs in Therapy
|
|
| September 15, 2005 (Vol. 25, No. 16) |
|
Applying Mass Spec Tools in Proteomics
|
|
Biomolecular Screening Technologies Advance
|
|
Flanders' Biotech Sector Comes of Age
|
|
Molecular Biology Software Product Update
Kevin Ahern
|
|
Microarrays for Model Organism Systems
|
|
Patent Law in India Focuses Strongly on R&D
|
|
Science and Democracy in Europe and the United States
|
|
Novel Tests Based on Genomic Markers
|
|
Casting a New Light on GPCR Targets
|
|
Lyophilization: Growing with Biotechnology
|
|
GEN's Spotlight on Wall Street News
|
|
| September 1, 2005 (Vol. 25, No. 15) |
|
Preparing for a Potential Pandemic
Gail Dutton
|
|
Funding Issues Slow Establishing Biobanks
|
|
In Silico Modeling Begins to Produce Results
Gail Dutton
|
|
Prion Disease Mechanisms and Activation
|
|
Outsourcing Drug Discovery & Development
|
|
Whole Genome Sequencing in 24 Hours
|
|
Advances in Protein Arrays Overcome Obstacles
Kathy Liszewski
|
|
Minnesota Toots Its Own Life Science Horn
|
|
The Scylla & Charybdis Face Integrated Genomics
|
|
Halting the March of Unreason
|
|
High-Sensitivity Mutation Scanning of Tumors
|
|
Utilizing a New Tool for Drug Discovery
|
|
Enhancing System Cleanliness & Drainability
|
|
Biotech and Pharma in a Turbulent World
|
|
| August 1, 2005 (Vol. 25, No. 14) |
|
Twenty-Five Years of Biotech Trends
Angelo DePalma, Ph.D.
|
|
Bioresearch Highlights Significance of SNPs
|
|
Drug Delivery Technology: Deals and Advances
|
|
Optimizing Strategies for Hit-to-Lead Process
|
|
Twists and Turns on the Path to Find New Drugs
|
|
North Carolina Leads Southeast in Biotech
|
|
Innovative Antibody Products and Therapeutics
|
|
Disposable Bioreactors Become Standard Fare
|
|
Safe Harbor Provisions for Preclinical Research
|
|
Taking a Journey-Based Approach to Manufacturing Development
|
|
Automating True Manual Patch Clamping
|
|
New Tool for Metabolic Disease Research
|
|
Animal-Derived Agents in Disposable Systems
|
|
Asia Offers Opportunities in Pharmaceuticals
|
|
| July 1, 2005 (Vol. 25, No. 13) |
|
Navigating Stem Cell Fact and Fiction
Gail Dutton
|
|
Developing Sophisticated Protein-Based Drugs
|
|
Tapping the Potential of Protein Drug Discovery
|
|
Peptide Manufacturers See Increased Growth
|
|
Biomagnetic Separations Move to Next Level
Gail Dutton
|
|
Authorized Generics: To Switch Rather than Fight
|
|
Evidence-based Medicine
|
|
Optimized Chemical Libraries in Drug Discovery
|
|
Targeted Disruption Using Group II Introns
|
|
High-Yield Single-Use Cell Culture Systems
|
|
| June 15, 2005 (Vol. 25, No. 12) |
|
FDA Needs to Balance Risks and Benefits for Patients
|
|
Applying Nanotech to Materials Research
Gail Dutton
|
|
New Biomanufacturing Opportunities & Challenges
Susan Aldridge, Ph.D.
|
|
PCR Gains Momentum with New Applications
|
|
High Demand for Target Validation Technologies
|
|
Using Complexity to Enhance Drug Discovery
|
|
Research Options for Structural Proteomics
Gail Dutton
|
|
Can India's IT Success be Replicated in Biotech?
|
|
Survey of European Scientists on Ethics of Scientific Advancements
|
|
Taking Computational Biology to the Bench
|
|
Miniaturized Filtration Assay for Discovery
|
|
Evaluation of the CellFerm-Pro STBR System
|
|
| June 1, 2005 (Vol. 25, No. 11) |
|
Optimizing the Drug Target Search
Susan Aldridge, Ph.D.
|
|
Greater Philly Region Grows as a Bio Cluster
|
|
Functional Genomics Reveals Mysteries of Genes
|
|
Ways to Overcome the Small Molecule Curse
|
|
Trends in Incubator and Shaker Technologies
|
|
Oligo Manufacturing Puts Emphasis on RNA
|
|
Mass Spectrometry in the Life Science Market
|
|
Examining NIH Policy to Enhance Public Access
|
|
Applying PAT to Oligonucleotide Synthesis
|
|
Microarray Data Management and Analysis
|
|
Integrated Workflow for Development Testing
|
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Anti-Cancer Therapy Success
John F. Wong, Ph.D.
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| May 15, 2005 (Vol. 25, No. 10) |
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Regulation of Combination Products by the FDA
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Medicinal Chemistry Equals New Leads
Susan Aldridge, Ph.D.
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Cutting Through the Biomarker Hype
Elizabeth Lipp
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Moving Toward System-Wide Software Suites
Gail Dutton
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Signal Pathways Making Inroads in Discovery
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Growth of Virginia's Life Science Clusters
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Preparation of Clinical Trials Materials
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| May 1, 2005 (Vol. 25, No. 9) |
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Making Innovation Work in Drug Discovery
Susan Aldridge, Ph.D.
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Creating and Educating a New Biotech Workforce
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In Vivo Molecular Imaging Poised for Growth
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Biosensors & Biomolecular Interaction Analysis
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Expansion of Proteomic Databases Needed
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Expansion of Proteomic Databases Needed
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Licensing Problems with Diagnostic Genetic Testing
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Opportunities and Challenges for Developing Functional Foods
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Outsourcing and Globalization in the Industry
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| April 15, 2005 (Vol. 25, No. 8) |
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Submitting Pharmacogenomic Data to the FDA
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Putting the Squeeze on Manufacturing
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Interfering with RNA
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NIH Ethics Regulations
Gail Dutton
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California Stem Cell Institute Starts Slowly
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Microarray Technologies Advancing Medicine
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Sample Management and Storage Systems
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Turbocharging Expression Microarrays
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Establishing a Biotech Industry in Singapore
Robert Yuan, Ph.D.
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Biotechnology in Vancouver
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Some Activist Groups Exibit a
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| April 1, 2005 (Vol. 25, No. 7) |
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Pharma Struggles with Negative Image
Gail Dutton
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U.S. HUPO Symposium Focuses on Proteomics
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Chemical Genomics Facilitates Finding Targets
Mary Addonizio
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Singapore Grooms Firms for Success
Robert Yuan, Ph.D.
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Trends in Viral Validation
Gail Dutton
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Michigan Life Sciences Industry Extends Roots
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Biotechs Focus on Critical Medical Needs
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Can a Strong Patent Position Be Illegal?
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Reducing Risk with
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| March 15, 2005 (Vol. 25, No. 6) |
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FDA Final Current Good Tissue Practice Rule
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Screening Technology Challenges
Susan Aldridge, Ph.D.
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Using Nanotechnologies In Biotech and Medicine
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Lab Automation 101: Effective Integration
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The Growing Allure of Rational Drug Design
Kathy Liszewski
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Biotech in Wales Quietly Thriving
Sophia Fox
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Addressing Stability of Biological Drugs
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Misplaced Attacks on the Pharmaceutical Industry
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| March 1, 2005 (Vol. 25, No. 5) |
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NIH's New Ethics Regulations
Gail Dutton
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Managing Cardiovascular Disease Risk Factors
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Phoenix Seeks to Advance its Biotech Initiative
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Protein-Protein Interactions in Drug Discovery
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The Spotlight Is on Protein-Folding Disorders
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Metabonomics Providing Clues to Discovery
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Race to Cut Whole Genome Sequencing Costs
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Strengthening Pharma and Biotech Patents
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Is Biotech in the Midst of a Fifty-Year Cycle?
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| February 15, 2005 (Vol. 25, No. 4) |
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FDA's Draft Guidance on Pharmacogenomics
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Manufacturing Biologicals Effectively
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Personalized Arthritis Therapy
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What it Costs fo Operate a Biotech Facility
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Staying Up-to-Date in Biomarker Research
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Is Biotechnology Complacent to PAT Principles?
Gail Dutton
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Conservative Outlook Seen at Investor Forum
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| February 1, 2005 (Vol. 25, No. 3) |
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Biobanking Emerging as a Key Growth Area
Susan Aldridge, Ph.D.
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Antibody Therapeutics Dominate Meeting
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High Throughput Screening of GPCRs
Kathy Liszewski
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Advances in Microgenomics: Less is More
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Atlanta Bioscience Breaks into the Top Ten
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Re-Engineering the Drug Development Pipeline
Mary Addonizio
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Could London Become a Major Biotech Hub?
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The Impact of Biotech Licensing
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| January 15, 2005 (Vol. 25, No. 2) |
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Taking a Look at FDA's Critical Path Initiative
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Pharmacogenomic Tests for Breast Cancer
Gail Dutton
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BIO-Europe Conference Gauges Future
Susan Aldridge, Ph.D.
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High Content Screening Management Options
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Microfluidics Technology Goes Mainstream
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Panning for Drug Discovery Gold with New Tools
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Agilent Advances Lab-on-a-Chip Technique
Susan Aldridge, Ph.D.
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Building Momentum in Scandinavian Cluster
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The Human Side of Science
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| January 1, 2005 (Vol. 25, No. 1) |
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Vioxx and Celebrex Bring Heat to the FDA
Gail Dutton
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U.K. to Push Bioprocessing to Forefront
Susan Aldridge, Ph.D.
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Obtaining High-Quality Protein Crystals
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Druggability: Prime Real Estate of the Genome
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Exploiting Post-Translational Modifications
Kathy Liszewski
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Progress in Vaccine and Gene Therapy Strategies
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Legal Uses of a Patented Invention in the U.S.
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Drug Importation Equals Bad Public and Economic Policy
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Clinical Data at ASH Boon to Wall St. Analysis
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