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June 1, Vol. 27, No. 11

  • Feature Articles

    • Biomanufacturing in Limelight
    • Susan Aldridge, Ph.D.
    • The recent “BioProcess International™ Conference and Exhibition,” held in Paris, provided a forum for updates in manufacturing and process development The world of biotech, monoclonals in particular, experienced bad press in March 2006, when six Phase I volunteers suffered extreme ... more »
    • DNA Chips Provide Key to Human Genome Analysis
    • Nina Flanagan
    • Although DNA microarrays are just beginning to be investigated for diagnostics, they are becoming key tools for preclinical and clinical research Gene-expression analysis continues to provide information on what is occurring on a molecular level and is crucial to discovering ... more »
    • Cellulosic Biofuels Abound with Promise
    • Gail Dutton
    • While ethanol is being heralded as the solution to the world’s energy concerns, developers are scrambling to replace corn in the US with more economical feedstocks and to develop more efficient production methods “Everybody has to look beyond oil,” insists ... more »
    • miRNA Becoming a Research Priority
    • Catherine Shaffer
    • Since they were first discovered in 1993, miRNAs have created a great deal of excitement These small pieces of RNA, only 21–22 nucleotides long, have emerged as potentially important regulators of cellular developmental pathways, proliferation, apoptosis, and differentiation They represent ... more »
    • SPR Expands the Knowledge of Proteins
    • Gail Dutton
    • Surface plasmon resonance (SPR) technology is expanding strategies for studying and analyzing binding kinetics, offering real-time, label-free analysis Researchers at the “Developments in Protein Interaction Analysis—DiPIA2007” conference sponsored by Biacore (wwwbiacorecom) and GE Healthcare (wwwgehealthcarecom), held in Phoenix in May, ... more »
    • Streamlining HPLC in Bioproduction
    • Angelo DePalma, Ph.D.
    • Like many other analysis platforms, HPLC was once considered a sophisticated method dominated by expert analysts or, at the very least, scientists willing to delve into an instrument’s innards Today, HPLC’s commodity status is generally viewed as a welcome development... more »
    • BIO 2007 Challenges Attendees to Innovate
    • Ilene Schneider
    • At “BIO 2007” in Boston, keynote speaker, actor Michael J Fox, threw down a drug development gauntlet to the biotech industry: “innovate and accelerate the translation of basic science into improved therapies for patients,” he said More than 200 breakout ... more »
    • Long-Term Time-Lapse Studies Focus on Cells
    • In our lab, we study the development of chicken skin appendages (feathers, scales) as a model for organogenesis We are interested in characterizing the cellular and molecular activities underlying the developmental process For this purpose, we commonly grow the skin ... more »