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May 1, Vol. 27, No. 9

  • Feature Articles

    • China Looks to Accelerate Globalization
    • Robert Yuan, Ph.D.
    • For multinational corporations, China is a critical stop in the drive toward globalization In part I of this three-part China series (GEN, April 15, 2007), I summarized the Chinese activities of several multinational corporations (MNC) In this article, part II ... more »
    • So, You Want to Be a Millionaire?
    • Gail Dutton
    • Plenty of people have made their fortunes in the competitive biotech environment with groundbreaking ideas and innovative products However, just as many with equally outstanding concepts and worthwhile products are struggling to show a profit, much less earn millions for ... more »
    • Navigating Complex Pathways in Cancer
    • Elizabeth Lipp
    • Despite decades of research, cancer remains the leading cause of death by disease in the western world However, advances in R&D as well as increased understanding of the complex pathways, molecular mechanisms, and pathophysiology of human cancer have opened up ... more »
    • Building Better Pipelines with ADME-Tox
    • Vicki Glaser
    • Realizing that a promising, effective drug has toxic side effects in humans, even if only in certain subpopulations, at certain doses, or in the presence of other drugs or co-morbidities, is a costly discovery, especially when it happens late in ... more »
    • Molecular Diagnostics Revamps Drug Development
    • Kate Marusina, Ph.D.
    • Molecular diagnostics uses molecular signatures for disease identification, monitoring treatment effectiveness and even predicting a patient’s response to a new treatment Although adoption of this technology in the clinical laboratory setting has been slower than anticipated, novel tools continue to ... more »
    • Protein Characterization Entering New Era
    • Nina Flanagan
    • Although mass spectrometry has facilitated protein identification and characterization via various techniques, many new approaches are becoming available The success of protein and peptide therapeutics is helping to drive technology forward According to a February 2007 market report by Data ... more »
    • BioSimilars Market Ripe for Expansion
    • Sue Pearson, Ph.D.
    • Therapeutic proteins are a $60-billion industry However, since 40% have lost their patent protection and more are soon to follow, producing biosimilars is now arousing great interest from generic manufacturers everywhere, warned Beatrice Muzard, equity analyst for pharmaceuticals at Ixis ... more »
  • Columns

    • Improving Pharma Process Operations
    • Sophia Fox
    • Already used by 11 of the world’s biggest pharmaceutical companies, the DynoChem (wwwscale-upcom) platform was developed to facilitate API process development and expedite scale-up DynoChem says the product represents a single platform for parameter fitting, simulation, and the optimization of ... more »
    • Gene Patents Jeopardize Genetic Testing
    • Roger Klein
    • As the use of genetic testing has become more frequent, holders of patents on genes, genetic variants, and their biological correlations are using the threat of litigation to force laboratories to stop performing genetic tests Some laboratories have already discontinued ... more »