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January 15, Vol. 27, No. 2

  • Feature Articles

    • BioMarket Trends: Cancer Vaccines Exhibit Potent...
    • Bruce Carlson
    • Cancer researchers have long struggled to recruit the body’s immune system to attack tumors while leaving healthy cells alone The vaccine approach can offer huge improvements over traditional chemotherapy and radiation, which kill healthy and diseased cells indiscriminately and carry ... more »
    • Business Savvy for UK Biotechs
    • Susan Aldridge, Ph.D.
    • Last month, the “London Biotechnology Network’s Sixth Annual Genesis Conference” took place amid concerns that too many UK biotechs are being bought out by their richer US counterparts Christopher Evans, DSc, founder of Merlin Biosciences, one of Europe’s largest specialist ... more »
    • Making Sense of HCS Information
    • Lakshmi Kamath
    • The pressure during drug discovery to detect failure compounds earlier and at decreased cost has increased the relevance of high-content screening (HCS), according to scientists who will be presenting papers at the upcoming Cambridge Healthtech Conference, “High-Content Screening and Analysis,” ... more »
    • RNAi-Based Gene Expression Manipulation
    • Trevor Stokes
    • RNAi adds insight not only to basic biology but also gives researchers a toolkit for RNAi-based gene expression manipulation The latest findings in the field were presented at Select Biosciences’ “RNAi Europe” conference held recently in Prague... more »
    • Laser-Capture Microdissection Advances
    • Kathy Liszewski
    • Laser capture microdissection (LCM) is emerging as a premier technology with a point-and-shoot capability designed to rapidly isolate single cells or unique multicellular structures from complex heterogeneous tissue The dissected sample can then undergo a battery of biochemical and molecular ... more »
    • Omics Prove Handy in Production Processes
    • Angelo DePalma, Ph.D.
    • Bioprocessors have always tested protein products during and after manufacturing, but it has only been a few years since terms like “process proteomics” have emerged to describe these activities Broadly speaking, process omics refers to the application of molecular analytical ... more »
    • Uniting Efforts in Molecular Medicine
    • Kenneth Buetow
    • Although cancer remains a leading cause of death in the United States, our understanding of the disease has leapt dramatically forward in recent years with the development of new technologies that enable researchers to understand its molecular origins... more »
  • Columns

    • Cell Therapeutics Counts on Drug Delivery
    • Carol Potera
    • When James Bianco, MD, and Jack Singer, MD, co-founded Cell Therapeutics (CTI; wwwcticseattlecom) in 1992, both were oncologists working at an institution that had won a Nobel Prize for pioneering dose-intensive chemotherapy However, looking 15 years ahead, “we didn’t think ... more »
    • Avastin Pads Genentech's Bottom Line
    • Querida Anderson
    • Genentech (wwwgenentechcom) is the fastest growing stock on the Zacks Focus List with a long-term growth rate of 2946%, according to a report from Zacks in December 2006 The company has met or exceeded Zacks’ estimates in 16 consecutive ... more »
    • Funding Challenges for Gene Therapy
    • Riku Rautsola
    • When it comes to biotechnology innovation, gene therapy and genetic medicine led the way in the early and mid 1990s The concept of gene therapy was viewed as the arrival of tomorrow’s medicine today The excitement surrounding the first gene ... more »