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Dec. 1, Vol. 26, No. 21

    • Columns

      • Abbreviated Approval of Generic Biologics
      • The creation of an abbreviated approval pathway for generic biologics, like that existing for the approval of generic versions of traditional drugs, is at long last the subject of pending legislation—Rep. Henry Waxman’s recently proposed Access to L ... more »
      • Bioanalytical Systems Targets CRO Niche
      • Peter Kissinger, Ph.D., started Bioanalytical Systems (BASi; www.bioanalytical.com) 32 years ago in his garage with just $365. He tinkered on his inventions in his spare time, as all researchers had to do before SBIR grants. Dr. Kissinger successfu ... more »
      • Market Research Tips for Suppliers
      • In the current life science business environment, new product development is swift, competition is fierce, and the marketplace is fragmented with multiple distribution channels. There is less room than ever for missteps. To capture a market leadersh ... more »
      • Recent Growth Sets Stage for Q4 2006
      • After biotech enjoyed its best quarter of the year, the Burrill Biotech Select Index recovered most of its value lost in the first two quarters and finished down just 9% from its 3Q 2005 value. Heading into the final quarter, momentum for biotech co ... more »
    • Feature Articles

      • BioMarket Trends
      • The life science tools industry consists of a broad range of companies providing technology solutions that form the basis for drug discovery, applied market testing (e.g., bio-defense, environmental, food, forensics, etc.), and basic scientific and ... more »
      • Collaborative Spirit Fosters Bioinformatics
      • Strategically located between the University of North Carolina at Chapel Hill, North Carolina State University, and Duke University, Research Triangle Park (RTP) has been a cornerstone of the biotechnology industry since its earliest days. More rece ... more »
      • Finding and Working with a Staffing Firm
      • Over the last decade, biotechnology companies have gained visibility as the investment community views the high potential return afforded by the expensive drugs they produce. With investors pumping so much money into research, biotech companies are ... more »
      • Gauging Nanobiotech's Promise Realistically
      • Biotech products based on nanotechnology are becoming more widespread, but not without first encountering substantial challenges. According to a report issued by the ETC Group (www.etcgroup.org/en), the major pharmaceutical companies generally have ... more »
      • Honing in on signal Transduction Pathways
      • Signal transduction is a key mechanism that brings about several physiological responses in a cell. Aberrant signaling can result due to gene mutations or regulatory protein overexpression. It is presumed that about 400 human diseases are due to sig ... more »
      • Lab Notebooks Offer Efficiency Gains
      • Gail Dutton
      • Laboratory notebooks contain a literal wealth of information to advance research enterprise-wide, to protect and support patents, and to streamline the regulatory submissions process—if only they could be easily accessed. For most companies, the ker ... more »
      • Minimizing Cost and Use of Purified Water
      • The pharmaceutical industry is facing strong and growing pressure to reduce the cost of producing drugs. One universal way to do that is to cut operating expenses, lowering the day-to-day costs of doing business. Minimizing energy and utility usage ... more »
      • Research Drives Microscopy Innovations
      • Elizabeth Lipp
      • Some time before 1668, Antony van Leeuwenhoek learned to grind lenses and make simple microscopes. Scientists have been looking through different versions of this imaging system ever since. There’s more to the 21st century microscope, however. The t ... more »
    • Tutorials

      • Basic Considerations for Laboratory Water
      • Water is probably the most commonly used laboratory reagent. However, it is often taken for granted and its potential impact on experimental outcomes overlooked. Understanding basic principles regarding laboratory water may help scientists avoid com ... more »
      • Finding Modulators of the Hh Pathway
      • It has been noted that there are several features shared between stem and tumor cells, including self-renewal and replication potential. It is believed that the early stage of oncogenesis involves acquisition of mutations in a single cell accumulate ... more »
      • Systems Biology Tools Get Personal
      • Over the last few years, we have witnessed the rapid evolution of software tools for functional analysis of microarray gene expression, proteomics, metabolomics and other omics data. Integrated data-mining platforms, such as MetaCore and MetaDrug ( ... more »

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