Leading the Way in Life Science Technologies

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Sep. 1, Vol. 26, No. 15

    • Columns

      • ChemDiv's Collaborative CRO Relationships
      • Biotechnology and pharmaceutical companies looking to outsource various stages of the drug discovery process can find a range of services at ChemDiv (www.chemdiv.com), based in San Diego and Moscow. This contract research organization (CRO) with a 1 ... more »
      • Current New Drug Application Requirements
      • Understanding the requirements behind the FDA’s New Drug Application process can save substantial time in the development of biopharmaceuticals and allow companies in the life sciences sector to appropriately plan strategies that will maximize effic ... more »
      • Novel Diagnostics Help Target Therapies
      • Diagnostic product revenues with genomics-based technologies are ramping up. The growth area in the IVD market for the next five years will be molecular tests for oncology and infectious diseases. Also, since industry and doctors have rediscovered t ... more »
    • Feature Articles

      • BioMarket Trends
      • With over 325 commercial suppliers of antibodies, selecting the right antibody brings to mind the famous lock-and-key analogy of antibody-antigen binding—how do scientists find the perfect match? BioInformatics surveyed 1,000 life scientists about t ... more »
      • Chinese Biogenerics and Protection of IP
      • Generic drugs represent one of the greatest values in the world’s healthcare business and are of profound significance in the area of biopharmaceuticals. Because biopharmaceuticals are currently among the most expensive therapeutics on the market, a ... more »
      • Diagnostics in Gene and Protein Expression
      • Molecular diagnostics is a blend of genomics and proteomics tools for studying gene and protein expression. It is well established in infectious disease diagnosis but is becoming increasingly important in the context of inherited genetic disorders, ... more »
      • Fluidics for qPCR, Diagnostics & Biodefense
      • Micro- and nanofluidics technologies are enabling highly parallel, rapid analytical processes in drug discovery. In addition to research applications, microfluidics is playing an increasingly important role in the development of highly sensitive poi ... more »
      • ISPE's Role in Pharma Industry's Transition
      • The pharmaceutical industry is at the beginning of a transition period in which major technological changes may significantly affect the industry, according to Gert Moelgaard, chairman of the International Society for Pharmaceutical Engineers (ISPE) ... more »
      • Myriad Options for Molecular Diagnostics
      • Gail Dutton
      • Biomarkers save money. That simple fact, coupled with a wealth of information to link specific diseases to particular biomarkers, is resulting in explosive growth for molecular diagnostics. “Molecular diagnostics is proving it can significantly low ... more »
      • Post-Translational Modification Approaches
      • One of the main goals of proteomics is to unravel the many modifications important for biological activity. Post-translational modifications (PTMs) extend the range of protein function by attaching it to other biochemical functional groups like phos ... more »
      • Reconfiguring Mass Spec Instrumentation
      • In the past year, various new products designed to make mass spectrometry (MS) faster, as well as more efficient, user-friendly, and practical in a clinical setting have been introduced. While the technology has long been in industrial labs, constit ... more »
      • VisualSonics Targets the Preclinical Area
      • VisualSonics (www.visualsonics.com) markets and develops high-resolution, micro-ultrasound imaging systems to life science researchers worldwide. The company launched its Vevo™ micro-ultrasound platform in 2003. By 2005, VisualSonics had sold over 2 ... more »
    • Tutorials

      • Automation of Protein Crystallography
      • Protein crystallography has significantly aided the understanding of human disease at a molecular level. As the knowledge of accurate molecular structures is a prerequisite for rational drug design, protein crystallography has also had a substantial ... more »
      • IntegratedProcess Design & Development
      • Process development and integration of unit operations during the drug development cycle for a typical microbial or mammalian cell culture process is important. Most biopharmaceutical companies have their own in-house process development programs. I ... more »
      • Physiologically Relevant HTS Technologies
      • The R&D productivity gap, or the increasing amount of pharmaceutical R&D spending relative to the number of new drug candidates introduced per year, has been widely discussed in the industry and media. Many companies are responding by reexam ... more »

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