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Jul. 1, Vol. 25, No. 13

    • Point of View

      • Evidence-based Medicine
      • How limited healthcare budgets can best be allocated at a time of skyrocketing costs is a question that dominates global public and private discourse. At the same time, expectations are high for good health, longevity, and access to innovative medic ... more »
    • Feature Articles

      • Biomagnetic Separations Move to Next Level
      • Gail Dutton
      • Merck Chimie ( introduced its new 1.2 to 1.5 m monodispersed superparamagnetic beads in June at its third international meeting in San Diego. According to Fabrice Sultan, Ph.D., sales and marketing manager, "Their COOH-modifi ... more »
      • Developing Sophisticated Protein-Based Drugs
      • Driven by technology, protein and peptide drug exploration has been fed by the success of the human genome project, striking improvements in technologies such as mass spectrometry, advances in molecular genetics, and progress in production technolog ... more »
      • Navigating Stem Cell Fact and Fiction
      • Gail Dutton
      • At a recent conference in Greece, a German researcher described his experience of being shouted down in his home country when he attempted to deliver an invited presentation on embryonic stem cells. On the other side of the world, Korean researchers ... more »
      • Peptide Manufacturers See Increased Growth
      • If you were to listen in at a gathering of executives from the contract peptide manufacturing sector, you might hear phrases like "extremely busy," or "saturated until well into next year," or "cautiously optimistic about th ... more »
      • Tapping the Potential of Protein Drug Discovery
      • Although protein drug discovery is still a new field, many companies are developing sophisticated technologies to enhance its potential. These companies will be presenting information on their most recent efforts at the upcoming "Drug Discovery ... more »
    • Legal Affairs

      • Authorized Generics: To Switch Rather than Fight
      • In Teva Pharmaceuticals Industries, Ltd. v. Crawford, decided this June, the U.S. Court of Appeals for the District of Columbia, in affirming a lower court decision, has potentially changed the landscape with respect to certain aspects of the 1984 H ... more »
    • Tutorials

      • High-Yield Single-Use Cell Culture Systems
      • Single-use cell culture systems are the hot topic of the moment, and with good reason. Disposable systems, such as T-flasks, roller bottles, and bags, can offer a variety of advantages over fully instrumented bioreactors. These benefits include elim ... more »
      • Optimized Chemical Libraries in Drug Discovery
      • New hits in drug discovery have traditionally been identified by screening a biological target with large chemical libraries that often contain more than a million compounds. This random screening is both costly and time-consuming. Additionally, the ... more »
      • Targeted Disruption Using Group II Introns
      • The completed sequencing of entire bacterial genomes and recent advances in genomics has allowed the identification of many genes. While several genes have been characterized, the function of the majority remains unknown. Bridging the gap between se ... more »


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