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May 1, Vol. 33, No. 9

  • Feature Articles

    • Critical Tools for Oligo Characterization
    • Angelo DePalma, Ph.D.
    • The emphasis on process understanding has been part of pharmaceutical development strategy since FDA’s 2003–2004 promulgation of GMPs for the 21st Century Oligonucleotides were almost nonexistent in major pharmacopoeias at the time Now that oligo drugs are nearing late development ... more »
    • Exposing the Exposome
    • Richard A. Stein
    • Understanding the interplay between genetic and environmental factors that shape phenotypes has represented, historically, a thought-provoking area for biomedical, medical, and social sciences... more »
    • Biomarkers Take Center Stage
    • Josh P. Roberts
    • Biomarkers by definition indicate some state or process that generally occurs at a spatial or temporal distance from the marker itself, and it would not be an exaggeration to say that biomedicine has become infatuated with them: Where to find ... more »
    • Separation of Therapeutic Biomolecules
    • Vicki Glaser
    • Hydrophobic-interaction chromatography and reversed-phase chromatography (HIC/RPC) for large-scale separation of proteins was the focus of a series of talks at Tosoh Bioscience’s recent “HIC/RPC Bioseparation Conference: Advancements, Applications and Theory in Downstream Processing”... more »